Search Results - "Waldmann, T.A."

Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens by Jabri, B, DePaolo, R. W, Abadie, V, Tang, F, Fehlner-Peach, H, Hall, J. A, Wang, W, Marietta, E. V, Kasarda, D. D, Waldmann, T. A, Murray, J. A, Semrad, C, Kupfer, S. S, Belkaid, Y, Guandalini, S

“…Under physiological conditions the gut-associated lymphoid tissues not only prevent the induction of a local inflammatory immune response, but also induce…”
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The 1.5 meter solar telescope GREGOR by Schmidt, W., von der Lühe, O., Volkmer, R., Denker, C., Solanki, S.K., Balthasar, H., Bello González, N., Berkefeld, Th, Collados, M., Fischer, A., Halbgewachs, C., Heidecke, F., Hofmann, A., Kneer, F., Lagg, A., Nicklas, H., Popow, E., Puschmann, K.G., Schmidt, D., Sigwarth, M., Sobotka, M., Soltau, D., Staude, J., Strassmeier, K.G., Waldmann, T.A.

“…The 1.5 m telescope GREGOR opens a new window to the understanding of solar small‐scale magnetism. The first light instrumentation includes the Gregor Fabry…”
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The role of emerging bipoles in the formation of a sunspot penumbra by Schlichenmaier, R., Bello González, N., Rezaei, R., Waldmann, T.A.

“…The generation of magnetic flux in the solar interior and its transport from the convection zone into the photosphere, the chromosphere, and the corona will be…”
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Frequent STAT5B mutations in γδ hepatosplenic T-cell lymphomas by Nicolae, A, Xi, L, Pittaluga, S, Abdullaev, Z, Pack, S D, Chen, J, Waldmann, T A, Jaffe, E S, Raffeld, M

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Intrathecal effects of daclizumab treatment of multiple sclerosis by BIELEKOVA, B, RICHERT, N, HERMAN, M. L, OHAYON, J, WALDMANN, T. A, MCFARLAND, H, MARTIN, R, BLEVINS, G

“…We previously reported that daclizumab, a humanized monoclonal antibody against CD25, reduced contrast-enhancing lesions (CEL) in patients with multiple…”
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Notch signaling contributes to proliferation and tumor formation of human T-cell leukemia virus type 1—associated adult T-cell leukemia by Pancewicz, Joanna, Taylor, John M., Datta, Abhik, Baydoun, Hicham H., Waldmann, Thomas A., Hermine, Olivier, Nicot, Christophe

“…The Notch signaling pathway plays an important role in cellular proliferation, differentiation, and apoptosis. Unregulated activation of Notch signaling can…”
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Augmented efficacy with the combination of blockade of the Notch-1 pathway, bortezomib and romidepsin in a murine MT-1 adult T-cell leukemia model by Yu, P, Petrus, M N, Ju, W, Zhang, M, Conlon, K C, Nakagawa, M, Maeda, M, Bamford, R N, Waldmann, T A

“…Adult T-cell leukemia (ATL) is an aggressive malignancy caused by human T-cell lymphotropic virus-1. There is no accepted curative therapy for ATL. We have…”
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Vaccination with tumor cells expressing IL-15 and IL-15Rα inhibits murine breast and prostate cancer by Morris, J C, Ramlogan-Steel, C A, Yu, P, Black, B A, Mannan, P, Allison, J P, Waldmann, T A, Steel, J C

“…A number of antitumor vaccines have recently shown promise in upregulating immune responses against tumor antigens and improving patient survival. In this…”
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Bismuth-212-Labeled Anti-Tac Monoclonal Antibody: α -Particle-Emitting Radionuclides as Modalities for Radioimmunotherapy by Kozak, Robert W., Atcher, Robert W., Gansow, Otto A., Friedman, Arnold M., Hines, John J., Waldmann, Thomas A.

“…Anti-Tac, a monoclonal antibody directed to the human interleukin 2 (IL-2) receptor, has been successfully conjugated to the α -particle-emitting radionuclide…”
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Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence by Datta, Abhik, Bellon, Marcia, Sinha-Datta, Uma, Bazarbachi, Ali, Lepelletier, Yves, Canioni, Danielle, Waldmann, Thomas A., Hermine, Olivier, Nicot, Christophe

“…The antiviral thymidine analog azidothymidine (AZT) is used to treat several virus-associated human cancers. However, to date the mechanism of AZT action…”
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Preparation of 211At-Labeled Humanized Anti-Tac Using 211At Produced in Disposable Internal and External Bismuth Targets by Schwarz, U.P., Plascjak, P., Beitzel, M.P., Gansow, O.A., Eckelman, W.C., Waldmann, T.A.

“…These studies describe the production and purification of 211At as well as the procedure for labeling humanized anti-Tac, the antibody to the α-chain of the…”
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T-cell receptors for cytokines: Targets for immunotherapy of leukemia/lymphoma by Waldmann, T.A.

“…Background: Cytokine receptors are exceptionally valuable targets for immunotherapy. For example, the high affinity IL-2 receptor is expressed by abnormal T…”
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The GREGOR telescope control system by Halbgewachs, C., Caligari, P., Glogowski, K., Heidecke, F., Knobloch, M., Mustedanagic, M., Volkmer, R., Waldmann, T.A.

“…This article describes the architecture of the new GREGOR telescope and its instrument control system. A short summary is given on the communication structure…”
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Antileukemic effect of daclizumab in CD25 high-expressing leukemias and impact of tumor burden on antibody dosing by Koon, H.B., Severy, P., Hagg, D.S., Butler, K., Hill, T., Jones, A.G., Waldmann, T.A., Junghans, R.P.

“…Humanized anti-CD25 antibody, daclizumab, was applied in a pilot study of 10 patients with CD25(+) leukemias and pharmacokinetic/pharmacodynamic properties…”
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A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin by Chaudhary, Vijay K, Queen, Gary, Junghans, Richard P, Waldmann, Thomas A, FitzGerald, David J, Pastan, Ira

“…Antibodies and growth factors have been chemically coupled to different toxins to produce cytotoxic molecules that selectively kill cells bearing appropriate…”
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The role of the gastrointestinal system in "idiopathic hypoproteinemia" by WALDMANN, T A, STEINFELD, J L, DUTCHER, T F, DAVIDSON, J D, GORDON, Jr, R S

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Preparation and in vivo evaluation of linkers for 211 At labeling of humanized anti-Tac by Yordanov, A.T., Garmestani, K., Zhang, M., Zhang, Z., Yao, Z., Phillips, K.E., Herring, B., Horak, E., Beitzel, M.P., Schwarz, U.P., Gansow, O.A., Plascjak, P.S., Eckelman, W.C., Waldmann, T.A., Brechbiel, M.W.

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Chromosomal Translocation in a Human Leukemic Stem-Cell Line Disrupts the T-Cell Antigen Receptor δ -Chain Diversity Region and Results in a Previously Unreported Fusion Transcript by Begley, C. G., Aplan, P. D., Davey, M. P., Nakahara, K., Tchorz, K., Kurtzberg, J., Hershfield, M. S., Haynes, B. F., Cohen, D. I., Waldmann, T. A., Kirsch, I. R.

“…We have studied a leukemic stem-cell line, DU.528, that is able to differentiate into myeloid and lymphoid cells. The leukemic cells have a translocation…”
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Monoclonal-antibody-mediated apoptosis in adult T-cell leukaemia by Debatin, K M, Goldmann, C K, Bamford, R, Waldmann, T A, Krammer, P H

“…The monoclonal antibody anti-APO-1 recognises a 52 kD cell membrane protein (APO-1) on some lymphoid tumour cell lines and on activated T cells. Binding of…”
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The multichain interleukin 2 receptor: A target for immunotherapy in lymphoma, autoimmune disorders, and organ allografts by Waldmann, T.A.

“…The use of chemotherapeutic agents has cured some types of human cancer. However, many types of cancer either are initially unresponsive or subsequently…”
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