Search Results - "Waldman, S. A."

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    Antiobesity Pharmacotherapy: New Drugs and Emerging Targets by Kim, GW, Lin, JE, Blomain, ES, Waldman, SA

    Published in Clinical pharmacology and therapeutics (01-01-2014)
    “…Obesity is a growing pandemic, and related health and economic costs are staggering. Pharmacotherapy, partnered with lifestyle modifications, forms the core of…”
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    Journal Article
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    Managing Innovation to Maximize Value Along the Discovery‐Translation‐Application Continuum by Waldman, SA, Terzic, A

    Published in Clinical pharmacology and therapeutics (01-01-2017)
    “…Success in pharmaceutical development led to a record 51 drugs approved in the past year, surpassing every previous year since 1950. Technology innovation…”
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    Clinical Pharmacology & Therapeutics: Past, Present, and Future by Waldman, SA, Terzic, A

    Published in Clinical pharmacology and therapeutics (01-03-2017)
    “…Clinical Pharmacology & Therapeutics (CPT), the definitive and timely source for advances in human therapeutics, transcends the drug discovery, development,…”
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    Peer Review Certifies Quality and Innovation in Clinical Pharmacology & Therapeutics by Waldman, SA, Terzic, A

    Published in Clinical pharmacology and therapeutics (01-09-2017)
    “…Clinical Pharmacology & Therapeutics (CPT) is an established voice of the discipline, a trusted source of new knowledge showcasing discovery, translation, and…”
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    Big Data Transforms Discovery-Utilization Therapeutics Continuum by Waldman, SA, Terzic, A

    Published in Clinical pharmacology and therapeutics (01-03-2016)
    “…Enabling omic technologies adopt a holistic view to produce unprecedented insights into the molecular underpinnings of health and disease, in part, by…”
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    Bioinnovation Enterprise: An engine driving breakthrough therapies by Waldman, SA, Terzic, A

    Published in Clinical pharmacology and therapeutics (01-01-2016)
    “…Biological advances have radically expanded our insights into the underpinnings of health and disease. New knowledge has formed the substrate for…”
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    Clinical Pharmacology & Therapeutics: The Next Five Years by Waldman, SA, Terzic, A

    Published in Clinical pharmacology and therapeutics (01-01-2015)
    “…It has been nearly ten years since we joined the editorial organization of Clinical Pharmacology & Therapeutics (CPT), as part of the American Society for…”
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    Molecular Insights Provide the Critical Path to Disease Mitigation by Waldman, SA, Terzic, A

    Published in Clinical pharmacology and therapeutics (01-01-2014)
    “…The revolution in scientific innovation, driven by the engines of enabling technologies, is increasingly capable of deconstructing complex disease processes…”
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    Advancing Pharmacometrics and Systems Pharmacology by Waldman, S A, Terzic, A

    Published in Clinical pharmacology and therapeutics (01-11-2012)
    “…Pharmacometrics and systems pharmacology are emerging as principal quantitative sciences within drug development and experimental therapeutics. In recognition…”
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    Bacterial Enterotoxins Are Associated with Resistance to Colon Cancer by Pitari, G. M., Zingman, L. V., Hodgson, D. M., Alekseev, A. E., Kazerounian, S., Bienengraeber, M., Hajnóczky, G., Terzic, A., Waldman, S. A.

    “…One half million patients suffer from colorectal cancer in industrialized nations, yet this disease exhibits a low incidence in underdeveloped countries. This…”
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    Guanylyl Cyclase C Agonists Regulate Progression through the Cell Cycle of Human Colon Carcinoma Cells by Pitari, G. M., Di Guglielmo, M. D., Park, J., Schulz, S., Waldman, S. A.

    “…The effects of Escherichia coli heat-stable enterotoxin (ST) and uroguanylin were examined on the proliferation of T84 and Caco2 human colon carcinoma cells…”
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    Guanylyl Cyclase Is an ATP Sensor Coupling Nitric Oxide Signaling to Cell Metabolism by Ruiz-Stewart, I., Tiyyagura, S. R., Lin, J. E., Kazerounian, S., Pitari, G. M., Schulz, S., Martini, E., Murad, F., Waldman, S. A.

    “…Defending cellular integrity against disturbances in intracellular concentrations of ATP ([ ATP]i) is predicated on coordinating the selection of substrates…”
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    Cancer Mucosa Antigens as a Novel Immunotherapeutic Class of Tumor-associated Antigen by Snook, A E, Eisenlohr, L C, Rothstein, J L, Waldman, S A

    Published in Clinical pharmacology and therapeutics (01-12-2007)
    “…Colorectal cancer is a leading cause of cancer‐related mortality worldwide. Surgery and chemoradiation exhibit incomplete efficacy and, ultimately, 50% of…”
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    Guanylyl Cyclase C is a Selective Marker for Metastatic Colorectal Tumors in Human Extraintestinal Tissues by Carrithers, S. L., Barber, M. T., Biswas, S., Parkinson, S. J., Park, P. K., Goldstein, S. D., Waldman, S. A.

    “…Guanylyl cyclase C (GCC) has been detected only in intestinal mucosa and colon carcinoma cells of placental mammals. However, this receptor has been identified…”
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    Managing the Innovation Supply Chain to Maximize Personalized Medicine by Waldman, S A, Terzic, A

    Published in Clinical pharmacology and therapeutics (01-02-2014)
    “…Personalized medicine epitomizes an evolving model of care tailored to the individual patient. This emerging paradigm harnesses radical technological advances…”
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