Search Results - "Walder, R Y"

Role of ASIC3 in the primary and secondary hyperalgesia produced by joint inflammation in mice by Ikeuchi, M., Kolker, S.J., Burnes, L.A., Walder, R.Y., Sluka, K.A.

“…The acid sensing ion channel 3 (ASIC3) is critical for the development of secondary hyperalgesia as measured by mechanical stimulation of the paw following…”
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Acid-sensing ion channel 3 expressed in type B synoviocytes and chondrocytes modulates hyaluronan expression and release by Kolker, S J, Walder, R Y, Usachev, Y, Hillman, J, Boyle, D L, Firestein, G S, Sluka, K A

“…Rheumatoid arthritis is an inflammatory disease marked by intra-articular decreases in pH, aberrant hyaluronan regulation and destruction of bone and…”
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Familial Hypomagnesemia Maps to Chromosome 9q, not to the X Chromosome: Genetic Linkage Mapping and Analysis of a Balanced Translocation Breakpoint by Walder, R.Y., Shalev, H., Brennan, T.M.H., Carmi, R., Elbedour, K., Scott, D.A., Hanauer, A., Mark, A.L., Patil, S., Stone, E.M., Sheffield, V.C.

“…Familial hypomagnesemia with secondary hypocalcemia (HSH) (MIM 307600) was studied in three inbred Bedouin kindreds from Israel. The three kindreds, one…”
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Role of RNase H in Hybrid-Arrested Translation by Antisense Oligonucleotides by Walder, Roxanne Y., Walder, Joseph A.

“…The mechanism of hybrid-arrested translation by antisense oligodeoxynucleotides has been investigated with the rabbit reticulocyte lysate system. The…”
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Mice defective in Trpm6 show embryonic mortality and neural tube defects by Walder, Roxanne Y., Yang, Baoli, Stokes, John B., Kirby, Patricia A., Cao, Xiao, Shi, Peijun, Searby, Charles C., Husted, Russell F., Sheffield, Val C.

“…The syndrome of hypomagnesemia with secondary hypocalcemia is caused by defective TRPM6. This protein is an ion channel that also contains a kinase in its…”
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Changes in the disposition of substance P in the rostral ventromedial medulla after inflammatory injury in the rat by Maduka, U.P, Hamity, M.V, Walder, R.Y, White, S.R, Li, Y, Hammond, D.L

“…Highlights • Peripheral inflammatory injury changes the disposition of Substance P (SubP) in the rostral ventromedial medulla (RVM). • Levels of SubP and Tac1…”
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Isolation and characterization of a new hemoglobin derivative cross-linked between the alpha chains (lysine 99 alpha 1----lysine 99 alpha 2) by Chatterjee, R, Welty, E V, Walder, R Y, Pruitt, S L, Rogers, P H, Arnone, A, Walder, J A

“…Bis(3,5-dibromosalicyl) fumarate and a number of related bifunctional reagents react preferentially with oxyhemoglobin to cross-link the beta chains within the…”
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Substrate specificity of human RNase H1 and its role in excision repair of ribose residues misincorporated in DNA by Eder, P S, Walder, R Y, Walder, J A

“…Recently we have shown that the major isoform of RNase H in human cells, RNase H1, is able to cleave DNA substrates containing a single RNA-DNA base pair, an…”
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HbXL99α : A Hemoglobin Derivative that is Cross-Linked between the α Subunits is Useful as a Blood Substitute by Snyder, Steven R., Welty, Emily V., Walder, Roxanne Y., Williams, Laura A., Walder, Joseph A.

“…Under deoxygenated conditions, bis(3,5-dibromosalicyl) fumarate reacts with hemoglobin selectively to cross-link the α subunits between Lys-α 199 and Lys-α…”
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Linkage of Infantile Bartter Syndrome with Sensorineural Deafness to Chromosome 1p by Brennan, Theresa M.H., Landau, Daniel, Shalev, Hana, Lamb, Fred, Schutte, Brian C., Walder, Roxanne Y., Mark, Allyn L., Carmi, Rivka, Sheffield, Val C.

“…Bartter syndrome (BS) is a family of disorders manifested by hypokalemic hypochloremic metabolic alkalosis with normotensive hyperreninemic hyperaldosteronism…”
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Kinetic analysis of Escherichia coli RNase H using DNA-RNA-DNA/DNA substrates by Hogrefe, H H, Hogrefe, R I, Walder, R Y, Walder, J A

“…The kinetic properties of Escherichia coli ribonuclease H (RNase H) were investigated using oligonucleotide substrates that consist of a short stretch of RNA,…”
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Use of PCR primers containing a 3'-terminal ribose residue to prevent cross-contamination of amplified sequences by WALDER, R. Y, HAYES, J. R, WALDER, J. A

“…Cross-contamination with previously amplified products poses a serious limitation in the use of PCR for clinical testing and in certain research applications…”
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Human hemoglobin expression in Escherichia coli: importance of optimal codon usage by Hernan, Ronald A, Hui, Hilda L, Andracki, Mark E, Noble, Robert W, Sligar, Stephen G, Walder, Joseph A, Walder, Roxanne Y

“…The overexpression of a nonfusion product of human beta-globin in Escherichia coli from its cDNA sequence has been accomplished for the first time. Expression…”
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The organization and complete nucleotide sequence of the PstI restriction-modification system by Walder, R Y, Walder, J A, Donelson, J E

“…We have determined the nucleotide sequence of a 4.0-kilobase DNA fragment containing the genes of the PstI restriction-modification system. Two large open…”
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Genetic Characterization of the 'New' Harlan Sprague Dawley Dahl Salt-Sensitive Rats by Walder, Roxanne Y, Morgan, Donald A, Haynes, William G, Sigmund, Rita D, McClain, Ann M, Stokes, John B, Mark, Allyn L

“…In 1994, it was reported that Dahl salt-sensitive SS/Jr rats supplied by Harlan Sprague Dawley were genetically contaminated and resistant to the pressor…”
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The 35-Nucleotide Spliced Leader Sequence is Common to All Trypanosome Messenger RNA's by Walder, Joseph A., Eder, Paul S., Engman, David M., Brentano, Steven T., Walder, Roxanne Y., Knutzon, Deborah S., Dorfman, David M., Donelson, John E.

“…In Trypanosomatidae the messenger RNA's (mRNA's) that code for the variant surface glycoproteins (VSG's), tubulins, calmodulin, and at least a subset of other…”
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Cloning of the MspI modification enzyme. The site of modification and its effects on cleavage by MspI and HpaII by Walder, R Y, Langtimm, C J, Chatterjee, R, Walder, J A

“…The gene for the MspI modification enzyme from Moraxella was cloned in Escherichia coli using the plasmid vector pBR322. Selection of transformants carrying…”
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Cloning and Expression of the Pst I Restriction-Modification System in Escherichia coli by Walder, Roxanne Y., Hartley, James L., Donelson, John E., Walder, Joseph A.

“…Here we report the cloning and preliminary characterization of the Pst I restriction-modification system of Providencia stuartii 164. Transformants of…”
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Structural features required for the reactivity and intracellular transport of bis(3,5-dibromosalicyl)fumarate and related anti-sickling compounds that modify hemoglobin S at the 2,3-diphosphoglycerate binding site by Chatterjee, R, Iwai, Y, Walder, R Y, Walder, J A

“…Bis(3,5-dibromosalicyl)fumarate (I) reacts preferentially with oxyhemoglobin to cross-link the two beta 82 lysine residues within the 2,3-diphosphoglycerate…”
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Oligodeoxynucleotide-directed mutagenesis using the yeast transformation system by Walder, R Y, Walder, J A

“…In this report we describe a highly efficient method for site-specific mutagenesis using the yeast transformation system. The method is based on the…”
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