Search Results - "Walden, Paul D."
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1
Interactions between β2-syntrophin and a family of microtubule-associated serine/threonine kinases
Published in Nature neuroscience (01-07-1999)Get full text
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2
Mechanistic investigation of the adrenergic induction of ventral prostate hyperplasia in mice
Published in The Prostate (15-02-2003)“…Background The norepinephrine (NE) analog phenylephrine has previously been shown to induce atypical prostate hyperplasia in rats. The objective of the present…”
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3
ART-27, an Androgen Receptor Coactivator Regulated in Prostate Development and Cancer
Published in The Journal of biological chemistry (02-04-2004)“…Androgen receptor trapped clone-27 (ART-27) is a newly described transcriptional coactivator that binds to the N terminus of the androgen receptor (AR). Given…”
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4
Use of CME to impact self-reported changes in the evaluation and management of anaemia in geriatric patients
Published in Journal of CME (01-01-2015)“…Objective. The Third US National Health and Nutrition Examination Survey (NHANES III) prompted the recognition of geriatric anaemia as a public health concern…”
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5
Regulation of de novo phosphatidylinositol synthesis
Published in Journal of lipid research (01-07-2006)“…Mechanisms that function to regulate the rate of de novo phosphatidylinositol (PtdIns) synthesis in mammalian cells have not been elucidated. In this study, we…”
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6
Interactive effects of 9-cis-retinoic acid and androgen on proliferation, differentiation, and apoptosis of LNCaP prostate cancer cells
Published in European journal of cancer prevention (01-01-2017)“…9-cis-Retinoic acid (9cRA), which binds to both retinoic acid receptors and retinoic X receptors, inhibits prostate cancer induction in rats and reduces growth…”
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7
Coexpression of MAST205 inhibits the activity of Na+/H+ exchanger NHE3
Published in American journal of physiology. Renal physiology (01-02-2006)“…Recent studies have shown that accessory proteins that interact with the apical Na(+)/H+ exchanger NHE3 are a vital part of the dynamic nature of the Na(+)/H+…”
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8
Loss of B-cell translocation gene-2 in estrogen receptor-positive breast carcinoma is associated with tumor grade and overexpression of cyclin D1 protein
Published in Cancer research (Chicago, Ill.) (15-07-2006)“…The B-cell translocation gene-2 (BTG2) is present in the nuclei of epithelial cells in many tissues, including the mammary gland where its expression is…”
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9
BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling
Published in Developmental biology (15-12-2005)“…The mouse prostate gland develops by branching morphogenesis from the urogenital epithelium and mesenchyme. Androgens and developmental factors, including…”
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10
Expression of the NF-κB-responsive gene BTG2 is aberrantly regulated in breast cancer
Published in Oncogene (28-10-2004)“…BTG2, a p53-inducible antiproliferative gene, is stimulated in breast cancer cells by activation of nuclear factor kappa B (NF-κB). In rat mammary glands, BTG2…”
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11
BTG2(TIS21/PC3) induces neuronal differentiation and prevents apoptosis of terminally differentiated PC12 cells
Published in Oncogene (03-10-2002)“…The p53-transcriptional target, BTG2(TIS21/PC3), was previously identified as an antiproliferative gene. However, the precise biological functions of the…”
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12
SOM230 Inhibits Insulin-Like Growth Factor-I Action in Mammary Gland Development by Pituitary Independent Mechanism: Mediated through Somatostatin Subtype Receptor 3?
Published in Molecular endocrinology (Baltimore, Md.) (01-02-2006)“…Somatostatin analogs (SAs) treat acromegaly by lowering pituitary GH secretion, which, in turn, lowers systemic IGF-I. The profound systemic effect is often…”
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13
Evidence That the Mammary Fat Pad Mediates the Action of Growth Hormone in Mammary Gland Development
Published in Endocrinology (Philadelphia) (01-02-1998)“…Recent evidence from our laboratory suggests that GH and insulin-like growth factor I (IGF-I) mediate glandular mammary development together with estrogen. It…”
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14
Induction of anoikis by doxazosin in prostate cancer cells is associated with activation of caspase-3 and a reduction of focal adhesion kinase
Published in Urolithiasis (01-08-2004)“…The quinazoline family of alpha1-blockers (prazosin, doxazosin, and terazosin) induce apoptosis of prostate cells through an alpha1-adrenoceptor-independent…”
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15
Antiproliferative B cell translocation gene 2 protein is down-regulated post-transcriptionally as an early event in prostate carcinogenesis
Published in Carcinogenesis (New York) (01-08-2001)“…B cell translocation gene 2 (BTG2) is a p53 target that negatively regulates cell cycle progression in response to DNA damage and other stress. The objective…”
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The Cooperative Prostate Cancer Tissue Resource: A specimen and data resource for Cancer researchers
Published in Clinical cancer research (15-07-2004)“…The Cooperative Prostate Cancer Tissue Resource (CPCTR) is a National Cancer Institute-supported tissue bank that provides large numbers of clinically…”
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Ex ante budget impact analysis (BIA) of PD-1 inhibitor toripalimab plus gemcitabine-cisplatin (T+GC) versus a simulated pembrolizumab regimen in first line (1L) treatment of recurrent or metastatic nasopharyngeal cancer (rmNPC)
Published in Journal of clinical oncology (01-06-2022)“…e18024 Background: Interim results of the JUPITER-02 randomized double-blind phase 3 trial demonstrated a PFS benefit for T+GC (11.7 m) vs placebo+GC (8m) in…”
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18
Chemoprevention strategies for prostate cancer
Published in European journal of cancer prevention (01-08-2002)“…Prostate cancer is the most common male malignancy in western countries. Although primary prevention of prostate cancer is not possible, screening using…”
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Microtubule-associated serine/threonine kinase-205 kDa and Fc gamma receptor control IL-12 p40 synthesis and NF-kappa B activation
Published in The Journal of immunology (1950) (15-02-2004)“…Stimulation of murine macrophages with LPS results in the coordinated activation of a set of proinflammatory cytokines and costimulatory molecules, including…”
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20
Lipid metabolism in phosphatidylinositol transfer protein α-deficient vibrator mice
Published in Biochemical and biophysical research communications (30-04-2004)“…Mice that are homozygous for the vibrator mutation express 65–85% less phosphatidylinositol transfer protein α (PITPα) than their wild type litter mates. By…”
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