Search Results - "Wal, Jean M"
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Precautionary allergen labelling: perspectives from key stakeholder groups
Published in Allergy (Copenhagen) (01-09-2015)“…Precautionary allergen labelling (PAL) was introduced by the food industry to help manage and communicate the possibility of reaction from the unintended…”
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Modifying the infant's diet to prevent food allergy
Published in Archives of disease in childhood (01-02-2017)“…Recommendations and guidelines on the prevention of food allergy have changed in recent decades. The aim of this review of the current evidence and ongoing…”
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Peanut allergens are rapidly transferred in human breast milk and can prevent sensitization in mice
Published in Allergy (Copenhagen) (01-07-2014)“…Food allergens have been evidenced in breast milk under physiological conditions, but the kinetic and the role of this passage in food allergies are still…”
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Allergenicity of peanut component Ara h 2: Contribution of conformational versus linear hydroxyproline-containing epitopes
Published in Journal of allergy and clinical immunology (01-05-2015)“…Background The 2S-albumin Ara h 2 is the most potent peanut allergen and a good predictor of clinical reactivity in allergic children. Posttranslational…”
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Effect of heating and glycation on the allergenicity of 2S albumins (Ara h 2/6) from peanut
Published in PloS one (25-08-2011)“…Peanut allergy is one of the most common and severe food allergies, and processing is known to influence the allergenicity of peanut proteins. We aimed to…”
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Cutaneous or respiratory exposures to peanut allergens in mice and their impacts on subsequent oral exposure
Published in International archives of allergy and immunology (01-01-2014)“…Recent data suggested that non-gastrointestinal exposure can lead to sensitisation to food allergens. We thus assessed the immune impact of respiratory or…”
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Endogenous allergens and compositional analysis in the allergenicity assessment of genetically modified plants
Published in Food and chemical toxicology (01-12-2013)“…•Endogenous allergenicity of GM plants is evaluated in the risk assessment process.•Historically, endogenous allergenicity has been evaluated using techniques…”
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Boiling peanut Ara h 1 results in the formation of aggregates with reduced allergenicity
Published in Molecular nutrition & food research (01-12-2011)“…Scope: Roasting rather than boiling and Maillard modifications may modulate peanut allergenicity. We investigated how these factors affect the allergenic…”
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Ninety-day oral toxicity studies on two genetically modified maize MON810 varieties in Wistar Han RCC rats (EU 7th Framework Programme project GRACE)
Published in Archives of toxicology (01-12-2014)“…The GMO Risk Assessment and Communication of Evidence (GRACE; www.grace-fp7.eu ) project is funded by the European Commission within the 7th Framework…”
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Trypsin resistance of the major peanut allergen Ara h 6 and allergenicity of the digestion products are abolished after selective disruption of disulfide bonds
Published in Molecular nutrition & food research (01-04-2012)“…Scope 2S‐albumins Ara h 2 and Ara h 6 are the most widely recognized and potent allergens for peanut‐allergic patients. These allergens are particularly…”
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Immunomodulatory Potential of Partially Hydrolyzed β‑Lactoglobulin and Large Synthetic Peptides
Published in Journal of agricultural and food chemistry (31-10-2012)“…The immunomodulatory potential of fragments derived from the cow’s milk allergen bovine β-lactoglobulin (BLG) was assessed in a mouse model of oral tolerance…”
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Goat's milk allergy without cow's milk allergy: suppression of non-cross-reactive epitopes on caprine β-casein
Published in Clinical and experimental allergy (01-04-2014)“…Summary Background and objective Goat's milk (GM) allergy associated with tolerance to cow's milk (CM) has been reported in patients without history of CM…”
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High-throughput NMR assessment of the tertiary structure of food allergens
Published in PloS one (02-07-2012)“…In vitro component-resolved diagnosis of food allergy requires purified allergens that have to meet high standards of quality. These include the authentication…”
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Contribution of Sequential and Conformational IgE-Binding Epitopes to the Allergenicity of Major Peanut Allergen Ara h 2
Published in Journal of allergy and clinical immunology (01-02-2014)Get full text
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Oral administration of recombinant Lactococcus lactis expressing bovine β-lactoglobulin partially prevents mice from sensitization
Published in Clinical and experimental allergy (01-04-2005)“…Summary Background The use of probiotics such as Lactococcus lactis and other lactic acid bacteria (LAB) has been proposed for the management of food allergy…”
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Use of Native Lactococci as Vehicles for Delivery of DNA into Mammalian Epithelial Cells
Published in Applied and Environmental Microbiology (01-11-2006)“…The use of the food-grade bacterium Lactococcus lactis as a DNA delivery vehicle at the mucosal level is an attractive DNA vaccination strategy. Previous…”
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Influence of the route of exposure and the matrix on the sensitisation potency of a major cows’ milk allergen
Published in Clinical and translational allergy (28-01-2015)“…Background Allergic sensitisation to food may occur through non‐gastrointestinal routes such as via skin or lung. We recently demonstrated in mice that…”
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Specificity of IgE antibodies from patients allergic to goat's milk and tolerant to cow's milk determined with plasmin-derived peptides of bovine and caprine β-caseins
Published in Molecular nutrition & food research (01-10-2012)“…Scope Despite a sequence homology of 90% between bovine and caprine β‐caseins (CN), IgE antibodies from patients allergic to goat's milk (GM), but tolerant to…”
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Oral tolerance and Treg cells are induced in BALB/c mice after gavagewith bovine beta-lactoglobulin
Published in Allergy (Copenhagen) (2011)“…Conclusion: For the first time, allergen-induced Treg cells that inhibited both the sensitization and the elicitation of the allergic reaction were evidenced…”
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Influence of the route of administration on immunomodulatory properties of bovine β-lactoglobulin-producing Lactobacillus casei
Published in Vaccine (25-09-2009)“…Abstract Because of their intrinsic immunomodulatory properties, some lactic acid bacteria were reported to modulate allergic immune responses in mice and…”
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