Search Results - "Wakim, Rima"

Workplace wellness across the lifespan: A pilot program for health promotion in a low- and middle-income country by Al Bizri, Ayah, Walani, Salimah, Nassar, Anwar, Saab, Bassem, Hanna Wakim, Rima, Noureddine, Abir, Chahrouri, Mario, Nakad, Pascale, Jaber, Dina, Yunis, Khalid

“…Abstract Considering that a sizable segment of the population spends significant amount of time at work, workplaces have been identified as practical platforms…”
Get full text

Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked–like disorder caused by loss-of-function mutations in LRBA by Charbonnier, Louis-Marie, PhD, Janssen, Erin, MD, PhD, Chou, Janet, MD, Ohsumi, Toshiro K., PhD, Keles, Sevgi, MD, Hsu, Joyce T., MD, Massaad, Michel J., PhD, Garcia-Lloret, Maria, MD, Hanna-Wakim, Rima, MD, Dbaibo, Ghassan, MD, Alangari, Abdullah A., MD, Alsultan, Abdulrahman, MD, Al-Zahrani, Daifulah, MD, Geha, Raif S., MD, Chatila, Talal A., MD, MSc

“…Background A number of heritable immune dysregulatory diseases result from defects affecting regulatory T (Treg) cell development, function, or both. They…”
Get full text

DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation by Jabara, Haifa H, McDonald, Douglas R, Janssen, Erin, Massaad, Michel J, Ramesh, Narayanaswamy, Borzutzky, Arturo, Rauter, Ingrid, Benson, Halli, Schneider, Lynda, Baxi, Sachin, Recher, Mike, Notarangelo, Luigi D, Wakim, Rima, Dbaibo, Ghassan, Dasouki, Majed, Al-Herz, Waleed, Barlan, Isil, Baris, Safa, Kutukculer, Necil, Ochs, Hans D, Plebani, Alessandro, Kanariou, Maria, Lefranc, Gerard, Reisli, Ismail, Fitzgerald, Katherine A, Golenbock, Douglas, Manis, John, Keles, Sevgi, Ceja, Reuben, Chatila, Talal A, Geha, Raif S

“…Dock8 deficiency leads to defects in humoral immunity. Geha and colleagues show that Dock88 interacts with MyD88 to bridge TLR9 signaling to the Src-Syk-STAT3…”
Get full text

Emergence of gram‐negative organisms as the cause of infections in patients with sickle cell disease by Khalife, Sara, Hanna‐Wakim, Rima, Ahmad, Rasha, Haidar, Rachid, Makhoul, Peter G., Khoury, Nabil, Dbaibo, Ghassan, Abboud, Miguel R.

“…Background Patients with sickle cell disease are at higher risk of infections with encapsulated bacteria due to immature immune responses and functional…”
Get full text

Questionnaire‐based survey in a developing country showing noncompliance with paediatric gastro‐oesophageal reflux practice guidelines by Manasfi, Hayat, Hanna‐Wakim, Rima, Akel, Imad, Yazbeck, Nadine

“…Aim This 2015 study investigated whether Lebanese paediatricians diagnosed and managed gastro‐oesophageal reflux disease (GERD) in infants and children in…”
Get full text

A Quality improvement initiative to reduce central line-associated bloodstream infections in a neonatal intensive care unit in a low-and-middle-income country by Al Bizri, Ayah, Hanna Wakim, Rima, Obeid, Alaa, Daaboul, Tania, Charafeddine, Lama, Mounla, Nabil, Nakad, Pascale, Yunis, Khalid

“…BackgroundPremature and sick neonates in the neonatal intensive care unit (NICU) are in need of central lines placing them at high risk of contracting a…”
Get full text

Epidemiology and characteristics of urinary tract infections in children and adolescents by Hanna-Wakim, Rima H, Ghanem, Soha T, El Helou, Mona W, Khafaja, Sarah A, Shaker, Rouba A, Hassan, Sara A, Saad, Randa K, Hedari, Carine P, Khinkarly, Rima W, Hajar, Farah M, Bakhash, Marwan, El Karah, Dima, Akel, Imad S, Rajab, Mariam A, Khoury, Mireille, Dbaibo, Ghassan S

“…Urinary tract infections (UTIs) are among the most common infections in the pediatric population. Over the last two decades, antibiotic resistance is…”
Get full text

Broad spectrum of autoantibodies in patients with Wiskott-Aldrich syndrome and X-linked thrombocytopenia by Crestani, Elena, MD, Volpi, Stefano, MD, Candotti, Fabio, MD, Giliani, Silvia, PhD, Notarangelo, Lucia Dora, MD, Chu, Julia, MD, Aldave Becerra, Juan Carlos, MD, Buchbinder, David, MD, Chou, Janet, MD, Geha, Raif S., MD, Kanariou, Maria, MD, King, Alejandra, MD, Mazza, Cinzia, PhD, Moratto, Daniele, PhD, Sokolic, Robert, MD, Garabedian, Elizabeth, RN, MSLS, Porta, Fulvio, MD, Putti, Maria Caterina, MD, Wakim, Rima H., MD, Tsitsikov, Erdyni, PhD, Pai, Sung-Yun, MD, Notarangelo, Luigi D., MD

“…Multiple immunologic abnormalities have been identified that might account for immune dysregulation in patients with WAS,5 including impaired function of…”
Get full text

Expanding the nude SCID/CID phenotype associated with FOXN1 homozygous, compound heterozygous, or heterozygous mutations by Giardino, Giuliana, Sharapova, Svetlana O., Ciznar, Peter, Dhalla, Fatima, Maragliano, Luca, Radha Rama Devi, Akella, Islamoglu, Candan, Ikinciogullari, Aydan, Haskologlu, Sule, Dogu, Figen, Hanna-Wakim, Rima, Dbaibo, Ghassan, Chou, Janet, Cirillo, Emilia, Borzacchiello, Carla, Kreins, Alexandra Y., Worth, Austen, Rota, Ioanna A., Marques, José G., Sayitoglu, Muge, Firtina, Sinem, Mahdi, Moaffaq, Geha, Raif, Neven, Bénédicte, Sousa, Ana E., Benfenati, Fabio, Hollander, Georg A., Davies, E. Graham, Pignata, Claudio

“…© The Author(s) 2021. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing,…”
Get full text

Hematopoietic stem cell transplantation outcomes for 11 patients with dedicator of cytokinesis 8 deficiency by Al-Herz, Waleed, MD, Chu, Julia I., MD, van der Spek, Jet, BSc, Raghupathy, Raj, PhD, Massaad, Michel J., PhD, Keles, Sevgi, MD, Biggs, Catherine M., MD, Cockerton, Lucinda, MSc, Chou, Janet, MD, Dbaibo, Ghassan, MD, Elisofon, Scott A., MD, Hanna-Wakim, Rima, MD, Kim, Heung Bae, MD, Lehmann, Leslie E., MD, McDonald, Douglas R., MD, PhD, Notarangelo, Luigi D., MD, Veys, Paul, MD, Chatila, Talal A., MD, Geha, Raif S., MD, Gaspar, H. Bobby, MD, Pai, Sung-Yun, MD

“…Background Dedicator of cytokinesis 8 (DOCK8) deficiency can be cured by allogeneic hematopoietic stem cell transplantation (HSCT). Reports of outcomes are…”
Get full text

Author Correction: DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation by Jabara, Haifa H., McDonald, Douglas R., Janssen, Erin, Massaad, Michel J., Ramesh, Narayanaswamy, Borzutzky, Arturo, Rauter, Ingrid, Benson, Halli, Schneider, Lynda, Baxi, Sachin, Recher, Mike, Notarangelo, Luigi D., Wakim, Rima, Dbaibo, Ghassan, Dasouki, Majed, Al-Herz, Waleed, Barlan, Isil, Baris, Safa, Kutukculer, Necil, Ochs, Hans D., Plebani, Alessandro, Kanariou, Maria, Lefranc, Gerard, Reisli, Ismail, Fitzgerald, Katherine A., Golenbock, Douglas, Manis, John, Keles, Sevgi, Ceja, Reuben, Chatila, Talal A., Geha, Raif S.

Get full text

Plasmacytoid dendritic cell depletion in DOCK8 deficiency: Rescue of severe herpetic infections with IFN-α 2b therapy by Keles, Sevgi, MD, Jabara, Haifa H., BSc, Reisli, Ismail, MD, McDonald, Douglas R., MD, PhD, Barlan, Isil, MD, Hanna-Wakim, Rima, MD, Dbaibo, Ghassan, MD, Lefranc, Gerard, PhD, Al-Herz, Waleed, MD, Geha, Raif S., MD, Chatila, Talal A., MD, MSc

Get full text

Decontamination of Dental Implant Surfaces by the Er:YAG Laser Beam: A Comparative in Vitro Study of Various Protocols by Nejem Wakim, Rima, Namour, Melanie, Nguyen, Hoang Viet, Peremans, Andre, Zeinoun, Toni, Vanheusden, Alain, Rompen, Eric, Nammour, Samir

“…Oral rehabilitation with dental implants has revolutionized the field of dentistry and has been proven to be an effective procedure. However, the incidence of…”
Get full text

Flow cytometry diagnosis of dedicator of cytokinesis 8 (DOCK8) deficiency by Pai, Sung-Yun, MD, de Boer, Helen, BSc, Massaad, Michel J., PhD, Chatila, Talal A., MD, Keles, Sevgi, MD, Jabara, Haifa H., BS, Janssen, Erin, MD, PhD, Lehmann, Leslie E., MD, Hanna-Wakim, Rima, MD, Dbaibo, Ghassan, MD, McDonald, Douglas R., MD, PhD, Al-Herz, Waleed, MD, Geha, Raif S., MD

“…DOCK8 could not be detected by flow cytometry in T cells, B cells, and CD34+ BM cells from 3 patients (Fig 1, B and data not shown). Because proteins in…”
Get full text

Approach to Non-Neutropenic Fever in Pediatric Oncology Patients-A Single Institution Study by Ali, Bilal Abou, Hirmas, Nader, Tamim, Hani, Merabi, Zeina, Hanna-Wakim, Rima, Muwakkit, Samar, Abboud, Miguel, Solh, Hassan El, Saab, Raya

“…Background Pediatric oncology patients with fever, even when not neutropenic, are known to be at an increased risk of bloodstream infections. However, there…”
Get full text

Increased blaOXA-23-like prevalence in Acinetobacter baumannii at a tertiary care center in Lebanon (2007-2013) by Kanj, Souha S, Tayyar, Ralph, Shehab, Marwa, El-Hafi, Bassam, Rasheed, Sari S, Kissoyan, Kohar Annie Berge, Kanafani, Zeina A, Wakim, Rima Hanna, Kara Zahreddine, Nada, Araj, George F, Dbaibo, Ghassan, Matar, Ghassan M

“…Acinetobacter baumannii has become one of the most feared organisms in hospital-acquired infections during the past decades. Their multi-drug resistant…”
Get full text

Device-associated infections in the pediatric intensive care unit at the American University of Beirut Medical Center by Ismail, Ali, El-Hage-Sleiman, Abdul-Karim, Majdalani, Marianne, Hanna-Wakim, Rima, Kanj, Souha, Sharara-Chami, Rana

“…Device-associated healthcare-associated infections (DA-HAIs) are the principal threat to patient safety in intensive care units (ICUs).  The primary objective…”
Get full text

A novel homozygous mutation in recombination activating gene 2 in 2 relatives with different clinical phenotypes: Omenn syndrome and hyper-IgM syndrome by Chou, Janet, MD, Hanna-Wakim, Rima, MD, Tirosh, Irit, MD, Kane, Jennifer, BA, Fraulino, David, BS, Lee, Yu Nee, PhD, Ghanem, Soha, MD, Mahfouz, Iman, MD, Mégarbané, André, MD, PhD, Lefranc, Gérard, PhD, Inati, Adlette, MD, Dbaibo, Ghassan, MD, Giliani, Silvia, PhD, Notarangelo, Luigi D., MD, Geha, Raif S., MD, Massaad, Michel J., PhD

“…Complete deficiency of either RAG1 or RAG2 results in classical severe combined immunodeficiency lacking T and B cells, since RAG1 mediates DNA binding and…”
Get full text

Viral Etiology of Acute Respiratory Infections in Pediatric Patients in Lebanon by Masoud, Khaldoun, Hanna-Wakim, Rima, Zaraket, Hassan, Kharroubi, Samer, Araj, George F, Matar, Ghassan M, Dbaibo, Ghassan

“…Acute respiratory infections (ARI) are the leading cause of death worldwide, especially among children. The majority of these infections in children are of…”
Get full text

Immune Responses to Mumps Vaccine in Adults Who Were Vaccinated in Childhood by Hanna-Wakim, Rima, Yasukawa, Linda L., Sung, Phillip, Arvin, Ann M., Gans, Hayley A.

“…Background. In a mumps outbreak in the United States, many infected individuals were adults who had received 2 doses of mumps vaccine. The persistence of…”
Get full text