Search Results - "Wakim, Matthew G"

Infusion System Carrier Flow Perturbations and Dead-Volume: Large Effects on Drug Delivery In Vitro and Hemodynamic Responses in a Swine Model by Lovich, Mark A., Pezone, Matthew J., Maslov, Mikhail Y., Murray, Michael R., Wakim, Matthew G., Peterfreund, Robert A.

“…BACKGROUND:We have previously shown that, at constant carrier flow, drug infusion systems with large dead-volumes (V) slow the time to steady-state drug…”
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Drug Infusion System Manifold Dead-Volume Impacts the Delivery Response Time to Changes in Infused Medication Doses In Vitro and Also In Vivo in Anesthetized Swine by Lovich, Mark A., Wakim, Matthew G., Wei, Abraham, Parker, Michael J., Maslov, Mikhail Y., Pezone, Matthew J., Tsukada, Hisashi, Peterfreund, Robert A.

“…IV infusion systems can be configured with manifolds connecting multiple drug infusion lines to transcutaneous catheters. Prior in vitro studies suggest that…”
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Computer Control of Drug Delivery by Continuous Intravenous Infusion: Bridging the Gap between Intended and Actual Drug Delivery by Parker, Michael J, Lovich, Mark A, Tsao, Amy C, Wei, Abraham E, Wakim, Matthew G, Maslov, Mikhail Y, Tsukada, Hisashi, Peterfreund, Robert A

“…BACKGROUND:Intravenous drug infusion driven by syringe pumps may lead to substantial temporal lags in achieving steady-state delivery at target levels when…”
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Myocardial drug distribution generated from local epicardial application: Potential impact of cardiac capillary perfusion in a swine model using epinephrine by Maslov, Mikhail Y., Edelman, Elazer R., Pezone, Matthew J., Wei, Abraham E., Wakim, Matthew G., Murray, Michael R., Tsukada, Hisashi, Gerogiannis, Iraklis S., Groothuis, Adam, Lovich, Mark A.

“…Prior studies in small mammals have shown that local epicardial application of inotropic compounds drives myocardial contractility without systemic side…”
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Nitrogen dioxide reducing ascorbic acid technologies in the ventilator circuit leads to uniform NO concentration during inspiration by Pezone, Matthew J., Wakim, Matthew G., Denton, Ryan J., Gamero, Lucas G., Roscigno, Robert F., Gilbert, Richard J., Lovich, Mark A.

“…Conventional inhaled NO systems deliver NO by synchronized injection or continuous NO flow in the ventilator circuitry. Such methods can lead to variable…”
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Inhaled Nitric Oxide Augments Left Ventricular Assist Device Capacity by Ameliorating Secondary Right Ventricular Failure by Lovich, Mark A, Pezone, Matthew J, Wakim, Matthew G, Denton, Ryan J, Maslov, Mikhail Y, Murray, Michael R, Tsukada, Hisashi, Agnihotri, Arvind K, Roscigno, Robert F, Gamero, Lucas G, Gilbert, Richard J

“…Clinical right ventricular (RV) impairment can occur with left ventricular assist device (LVAD) use, thereby compromising the therapeutic effectiveness. The…”
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Computer Control of Drug Delivery by Continuous Intravenous Infusion by Parker, Michael J., Lovich, Mark A., Tsao, Amy C., Wei, Abraham E., Wakim, Matthew G., Maslov, Mikhail Y., Tsukada, Hisashi, Peterfreund, Robert A.

“…Abstract Background: Intravenous drug infusion driven by syringe pumps may lead to substantial temporal lags in achieving steady-state delivery at target…”
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