Search Results - "Wakida, Nicole M"
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Phagocytic response of astrocytes to damaged neighboring cells
Published in PloS one (30-04-2018)“…This study aims to understand the phagocytic response of astrocytes to the injury of neurons or other astrocytes at the single cell level. Laser nanosurgery…”
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2
Polarity reveals intrinsic cell chirality
Published in Proceedings of the National Academy of Sciences - PNAS (29-05-2007)“…Like blood neutrophils, dHL60 cells respond to a uniform concentration of attractant by polarizing in apparently random directions. How each cell chooses its…”
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Fluid Shear Stress Enhances the Phagocytic Response of Astrocytes
Published in Frontiers in bioengineering and biotechnology (11-11-2020)“…Astrocytes respond to brain injury at a cellular level by the process of reactive astrogliosis, and are able to adjust their response according to the severity…”
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4
An intact centrosome is required for the maintenance of polarization during directional cell migration
Published in PloS one (23-12-2010)“…Establishing and maintaining polarization is critical during cell migration. It is known that the centrosome contains numerous proteins whose roles of…”
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Calcium Dynamics in Astrocytes During Cell Injury
Published in Frontiers in bioengineering and biotechnology (27-08-2020)“…The changes in intracellular calcium concentration ([Ca 2+ ]) following laser-induced cell injury in nearby cells were studied in primary mouse astrocytes…”
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Laser nanosurgery of single microtubules reveals location-dependent depolymerization rates
Published in Journal of biomedical optics (01-03-2007)“…In this study, 532-nm picosecond and 800-nm femtosecond lasers are used in combination with fluorescently labeled tubulin to further elucidate microtubule…”
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7
Combining quantitative phase microscopy and laser-induced shockwave for the study of cell injury
Published in Biomedical optics express (01-07-2021)“…In this paper, we propose a new system for studying cellular injury. The system is a biophotonic work station that can generate Laser-Induced Shockwave (LIS)…”
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Application of Laser Microirradiation in the Investigations of Cellular Responses to DNA Damage
Published in Frontiers in physics (25-01-2021)“…Since the laser has been invented it has been highly instrumental in ablating different parts of the cell to test their functionality. Through induction of…”
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Diminished LC3-Associated Phagocytosis by Huntington's Disease Striatal Astrocytes
Published in Journal of Huntington's disease (01-01-2022)“…In recent years the functions of astrocytes have shifted from conventional supportive roles to also include active roles in altering synapses and engulfment of…”
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Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage
Published in Journal of visualized experiments (31-01-2018)“…DNA damage induces specific signaling and repair responses in the cell, which is critical for protection of genome integrity. Laser microirradiation became a…”
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Laser-Induced Nuclear Damage Signaling and Communication in Astrocyte Networks Through Parp-Dependent Calcium Oscillations
Published in Frontiers in physics (27-04-2021)“…Astrocytes are known to respond to various perturbations with oscillations of calcium, including to cellular injury. Less is known about astrocytes’ ability to…”
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Recruitment of DNA damage recognition and repair pathway proteins following near-IR femtosecond laser irradiation of cells
Published in Journal of biomedical optics (01-03-2007)“…An 800-nm 200-fs laser is used to produce DNA damage in rat kangaroo (PtK1) and human cystic fibrosis pancreatic adenoma carcinoma (CFPAC-1) cells…”
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