Search Results - "Wakasugi, Tetsuro"
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TRPA1/M8 agonists upregulate ciliary beating through the pannexin-1 channel in the human nasal mucosa
Published in Molecular biology reports (01-03-2023)“…Background Nasal breathing is important for maintaining physiological respiration. However, airflow in the nasal cavity has an inherent cooling effect and may…”
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2
Nasal polyps show decreased mucociliary transport despite vigorous ciliary beating
Published in Brazilian journal of otorhinolaryngology (01-03-2024)“…•Mucociliary transport velocity of nasal polyps was lower than that of turbinates.•Ciliary beat frequency did not differ between the two tissues.•Expression of…”
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Pattern of Recurrence After Platinum-Containing Definitive Therapy and Efficacy of Salvage Treatment for Recurrence in Patients with Squamous Cell Carcinoma of the Head and Neck
Published in Frontiers in oncology (04-07-2022)“…In first-line systemic therapy for unresectable recurrent and/or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN), regimens are generally…”
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4
Decreased CFTR/PPARγ and increased transglutaminase 2 in nasal polyps
Published in Auris, nasus, larynx (01-12-2022)“…Transglutaminase (TGM)2 and peroxisome proliferator-activated receptor (PPAR)γ are thought to participate in the pathogenesis of nasal polyp formation in…”
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Comparison of 2 and 4 Intratympanic Steroid Injections in the Treatment of Idiopathic Sudden Sensorineural Hearing Loss
Published in Annals of otology, rhinology & laryngology (01-04-2018)“…Objective: We studied the effect of intratympanic steroid administration with different total injection times on hearing outcomes in patients with idiopathic…”
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6
Role of ZNF143 in tumor growth through transcriptional regulation of DNA replication and cell‐cycle‐associated genes
Published in Cancer science (01-12-2010)“…The cell cycle is strictly regulated by numerous mechanisms to ensure cell division. The transcriptional regulation of cell‐cycle‐related genes is poorly…”
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7
Decreased ciliary beat responsiveness to acetylcholine in the nasal polyp epithelium
Published in Clinical otolaryngology (01-05-2019)“…Objective We investigated the difference in ciliary beat responsiveness to acetylcholine in ex vivo and the difference in the expressions of associated…”
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Acetylcholine-induced Ciliary Beat of the Human Nasal Mucosa Is Regulated by the Pannexin-1 Channel and Purinergic P2X Receptor
Published in American journal of rhinology & allergy (01-07-2018)“…Background Airway mucociliary transport is an important function for the clearance of inhaled foreign particulates in the respiratory tract. The present study…”
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Video-Assisted Thyroidectomy Using a Surgical Energy Device: Initial Experience in a Japanese Single-Center Cohort
Published in Biomedicine hub (01-09-2021)“…Objective: Video-assisted thyroidectomy (VAT) was approved for coverage under the Japanese public health insurance system in 2016. In our department, we…”
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10
Characteristics of diffusion-weighted images and apparent diffusion coefficients of ranulas and other masses in and around the floor of the mouth
Published in Oral surgery, oral medicine, oral pathology and oral radiology (01-01-2019)“…The aim of this study was to evaluate the characteristics of diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) values of ranulas. In…”
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Impact of prophylactic percutaneous endoscopic gastrostomy tube placement on treatment tolerance in head and neck cancer patients treated with cetuximab plus radiation
Published in Japanese journal of clinical oncology (01-09-2016)“…We conducted a retrospective analysis to evaluate the efficacy and safety of cetuximab plus radiation with or without prophylactic percutaneous endoscopic…”
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12
Calmodulin and protein kinases A/G mediate ciliary beat response in the human nasal epithelium
Published in International forum of allergy & rhinology (01-11-2019)“…Background Mucociliary clearance of the airway epithelium is an essential function for mucosal defense. We recently proposed a hypothetical mechanism of…”
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13
Incidence and Risk Factors of Hypomagnesemia in Head and Neck Cancer Patients Treated with Cetuximab
Published in Frontiers in oncology (14-09-2016)“…Hypomagnesemia is a common adverse event during cetuximab (Cmab) treatment. However, few reports have investigated the incidence and risk factors of…”
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Pharmacokinetics of initial full and subsequent reduced doses of S-1 in patients with locally advanced head and neck cancer-effect of renal insufficiency
Published in Japanese journal of clinical oncology (01-05-2017)“…S-1 is a combination of tegafur [metabolized to 5-fluorouracil (5-FU)] with the modulators gimeracil (5-chloro-2,4-dihydroxypyridine) and oteracil potassium…”
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15
Possible participation of acidic pH in bone resorption in middle ear cholesteatoma
Published in The Laryngoscope (01-01-2014)“…Objectives/Hypothesis The etiopathology of bone resorption in cholesteatoma is unclear. We studied pH in middle ear cholesteatoma tissue and the permeability…”
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Possible contribution of pannexin‐1 to ATP release in human upper airway epithelia
Published in Physiological reports (01-02-2014)“…Pannexins are a family of transmembrane nonselective channel proteins that participate in the release of ATP into extracellular space. Previous studies have…”
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Different expressions of erbB1/2 and tight junction proteins in hypertrophic inferior turbinates and nasal polyps
Published in European archives of oto-rhino-laryngology (01-03-2013)“…Both inferior turbinate hypertrophy and nasal polyp formation entail the enlargement of the nasal mucosa caused by rhinosinusitis, but their macro/microscopic…”
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Synergism of Staphylococcus aureus colonization and allergic reaction in the nasal cavity in mice
Published in International archives of allergy and immunology (01-01-2012)“…The aim of this study is to investigate the reciprocal effect of Staphylococcus aureus colonization and allergic rhinitis in an allergy model of mice. BALB/c…”
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Identification of pannexins in rat nasal mucosa
Published in Allergy & rhinology (Providence, R.I.) (01-01-2013)“…Pannexins are a second family of gap-junction proteins in vertebrates, classified as pannexin-1, pannexin-2, and pannexin-3. Pannexin-1 is one of the…”
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DNA topoisomerase inhibitor, etoposide, enhances GC‐box‐dependent promoter activity via Sp1 phosphorylation
Published in Cancer science (01-06-2007)“…Modification of transcription factors by anticancer agents plays an important role in both apoptotic and survival signaling. Here we report that both DNA…”
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