Search Results - "Wakai, D."

High temporal and spatial quality petawatt-class Ti:sapphire chirped-pulse amplification laser system by Kiriyama, Hiromitsu, Mori, Michiaki, Nakai, Y, Shimomura, T, Sasao, H, Tanoue, M, Kanazawa, S, Wakai, D, Sasao, F, Okada, H, Daito, I, Suzuki, M, Kondo, S, Kondo, K, Sugiyama, A, Bolton, P R, Yokoyama, A, Daido, H, Kawanishi, S, Kimura, T, Tajima, T

“…Optical parametric chirped-pulse amplification (OPCPA) operation with low gain by seeding with high-energy, clean pulses is shown to significantly improve the…”
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Application of laser-accelerated protons to the demonstration of DNA double-strand breaks in human cancer cells by Yogo, A., Sato, K., Nishikino, M., Mori, M., Teshima, T., Numasaki, H., Murakami, M., Demizu, Y., Akagi, S., Nagayama, S., Ogura, K., Sagisaka, A., Orimo, S., Nishiuchi, M., Pirozhkov, A. S., Ikegami, M., Tampo, M., Sakaki, H., Suzuki, M., Daito, I., Oishi, Y., Sugiyama, H., Kiriyama, H., Okada, H., Kanazawa, S., Kondo, S., Shimomura, T., Nakai, Y., Tanoue, M., Sasao, H., Wakai, D., Bolton, P. R., Daido, H.

“…We report the demonstrated irradiation effect of laser-accelerated protons on human cancer cells. In vitro (living) A549 cells are irradiated with…”
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Oxidation resistance of Be12Ti fabricated by plasma-sintering method by Wada, K., Munakata, K., Kim, J.H, Yonehara, K., Wakai, D., Nakamichi, M.

“…Titanium beryllium intermetallic compounds (beryllides), such as Be12Ti, are alternatives to metallic beryllium as the neutron multiplier for the fusion…”
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Electron optical injection with head-on and countercrossing colliding laser pulses by Kotaki, H, Daito, I, Kando, M, Hayashi, Y, Kawase, K, Kameshima, T, Fukuda, Y, Homma, T, Ma, J, Chen, L-M, Esirkepov, T Zh, Pirozhkov, A S, Koga, J K, Faenov, A, Pikuz, T, Kiriyama, H, Okada, H, Shimomura, T, Nakai, Y, Tanoue, M, Sasao, H, Wakai, D, Matsuura, H, Kondo, S, Kanazawa, S, Sugiyama, A, Daido, H, Bulanov, S V

“…A high stability electron bunch is generated by laser wakefield acceleration with the help of a colliding laser pulse. The wakefield is generated by a laser…”
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Focusing and spectral enhancement of a repetition-rated, laser-driven, divergent multi-MeV proton beam using permanent quadrupole magnets by Nishiuchi, M., Daito, I., Ikegami, M., Daido, H., Mori, M., Orimo, S., Ogura, K., Sagisaka, A., Yogo, A., Pirozhkov, A. S., Sugiyama, H., Kiriyama, H., Okada, H., Kanazawa, S., Kondo, S., Shimomura, T., Tanoue, M., Nakai, Y., Sasao, H., Wakai, D., Sakaki, H., Bolton, P., Choi, I. W., Sung, J. H., Lee, J., Oishi, Y., Fujii, T., Nemoto, K., Souda, H., Noda, A., Iseki, Y., Yoshiyuki, T.

“…A pair of conventional permanent magnet quadrupoles is used to focus a 2.4 MeV laser-driven proton beam at a 1 Hz repetition rate. The magnetic field strengths…”
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Measured and simulated transport of 1.9 MeV laser-accelerated proton bunches through an integrated test beam line at 1 Hz by Nishiuchi, M., Sakaki, H., Hori, T., Bolton, P. R., Ogura, K., Sagisaka, A., Yogo, A., Mori, M., Orimo, S., Pirozhkov, A. S., Daito, I., Kiriyama, H., Okada, H., Kanazawa, S., Kondo, S., Shimomura, T., Tanoue, M., Nakai, Y., Sasao, H., Wakai, D., Daido, H., Kondo, K., Souda, H., Tongu, H., Noda, A., Iseki, Y., Nagafuchi, T., Maeda, K., Hanawa, K., Yoshiyuki, T., Shirai, T.

“…A laser-driven repetition-rated 1.9 MeV proton beam line composed of permanent quadrupole magnets (PMQs), a radio frequency (rf) phase rotation cavity, and a…”
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Demonstration of a temporally and spatially high quality petawatt-class laser system by Kiriyama, H, Mori, M, Nakai, Y, Shimomura, T, Sasao, H, Tanaka, M, Ochi, Y, Tanoue, M, Okada, H, Kanazawa, S, Sagisaka, A, Daito, I, Wakai, D, Sasao, F, Suzuki, M, Kondo, K, Sugiyama, A, Bulanov, S, Bolton, P R, Daido, H, Yokoyama, A, Kawanishi, S, Tajima, T

“…We report the demonstration of over 30-J of uncompressed broadband energy, indicating the potential peak power in excess of 500-TW with high temporal-contrast…”
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High levels of sphingolipids in human breast cancer by Nagahashi, Masayuki, MD, PhD, Tsuchida, Junko, MD, Moro, Kazuki, MD, Hasegawa, Miki, MD, PhD, Tatsuda, Kumiko, MD, Woelfel, Ingrid A., BS, Takabe, Kazuaki, MD, PhD, FACS, Wakai, Toshifumi, MD, PhD, FACS

“…Abstract Background Sphingolipids, including sphingosine-1-phosphate (S1P) and ceramide, have emerged as key regulatory molecules that control various aspects…”
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Polycystic kidneys and aneurysms by Wakai, S

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A Randomized Trial of Single-Dose Oral Dexamethasone Versus Multidose Prednisolone for Acute Exacerbations of Asthma in Children Who Attend the Emergency Department by Cronin, John J., MB, AFRCSI, McCoy, Siobhan, RGN, RCN, Kennedy, Una, FRCEM, an Fhailí, Sinéad Nic, PhD, MICR, Wakai, Abel, MD, FRCEM, Hayden, John, BPharm, Crispino, Gloria, PhD, CStat, Barrett, Michael J., MB, MRCPI, Walsh, Sean, FRCEM, O’Sullivan, Ronan, FPAEDS, MBA

“…Study objective In acute exacerbations of asthma in children, corticosteroids reduce relapses, subsequent hospital admission, and the need for ß2 -agonist…”
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A Case of a Pneumocystis Pneumonia Twenty-four Years After Living Kidney Transplantation Due to Withdrawal of Sulfamethoxazole/Trimethoprim Prophylaxis by Kono, Momoko, Kojima, Kaori, Wakai, Sachiko, Shirakawa, Hiroki

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Adult Living Donor Liver Transplantation for Patients With Portal Vein Thrombosis: A Single-center Experience by Miura, Kohei, Sugawara, Yasuhiko, Uchida, Koushi, Kawabata, Seiichi, Yoshii, Daiki, Isono, Kaori, Hayashida, Shintaro, Ohya, Yuki, Yamamoto, Hidekazu, Kobayashi, Takashi, Wakai, Toshifumi, Inomata, Yukihiro, Hibi, Taizo

“…Living donor liver transplantation (LDLT) for patients with portal vein thrombosis (PVT) is associated with several technical challenges for its complicated…”
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Utility of comprehensive genomic sequencing for detecting HER2-positive colorectal cancer by Shimada, Yoshifumi, MD, PhD, Yagi, Ryoma, MD, Kameyama, Hitoshi, MD, PhD, Nagahashi, Masayuki, MD, PhD, Ichikawa, Hiroshi, MD, PhD, Tajima, Yosuke, MD, Okamura, Takuma, MD, PhD, Nakano, Mae, MD, PhD, Nakano, Masato, MD, PhD, Sato, Yo, MD, Matsuzawa, Takeaki, MD, PhD, Sakata, Jun, MD, PhD, Kobayashi, Takashi, MD, PhD, Nogami, Hitoshi, MD, PhD, Maruyama, Satoshi, MD, PhD, Takii, Yasumasa, MD, PhD, Kawasaki, Takashi, MD, PhD, Homma, Kei-ichi, MD, PhD, Izutsu, Hiroshi, Kodama, Keisuke, Ring, Jennifer E., PhD, Protopopov, Alexei, PhD, Lyle, Stephen, MD, PhD, Okuda, Shujiro, PhD, Akazawa, Kohei, PhD, Wakai, Toshifumi, MD, PhD

“…HER2-targeted therapy is considered effective for KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (CRC). In general, HER2 status is…”
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Demonstration of high peak power, high contrast OPCPA/Ti:sapphire hybrid laser system by Kiriyama, H., Mori, M., Nakai, Y., Shimomura, T., Tanoue, M., Okada, H., Kondo, S., Kanazawa, S., Sagisaka, A., Daito, I., Nishiuchi, M., Ogura, K., Orimo, S., Pirozhkov, A.S., Kotaki, H., Sasao, H., Wakai, D., Tanaka, M., Ochi, Y., Suzuki, M., Sugiyama, A., Daido, H., Bulanov, S., Koike, M., Bolton, P.R., Kawanishi, S.

“…We have demonstrated over 30 J broadband output energy based on optical parametric chirped-pulse amplification (OPCPA) and Ti:sapphire chirped-pulse…”
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Prognostic significance of peritoneal lavage cytology at three cavities in patients with gastric cancer by Kano, Yosuke, MD, Kosugi, Shin-ichi, MD, PhD, Ishikawa, Takashi, MD, PhD, Otani, Takahiro, MD, Muneoka, Yusuke, MD, Sato, Yu, MD, Hanyu, Takaaki, MD, PhD, Hirashima, Kotaro, MD, PhD, Bamba, Takeo, MD, PhD, Wakai, Toshifumi, MD, PhD, FACS

“…Background We sought to determine the prognostic significance of intraoperative peritoneal lavage cytology (CY) at 3 different abdominal cavities and establish…”
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Impact of Thin-Section Computed Tomography-Determined Combined Pulmonary Fibrosis and Emphysema on Outcomes Among Patients With Resected Lung Cancer by Hashimoto, Naozumi, MD, PhD, Iwano, Shingo, MD, PhD, Kawaguchi, Koji, MD, PhD, Fukui, Takayuki, MD, PhD, Fukumoto, Koichi, MD, PhD, Nakamura, Shota, MD, PhD, Mori, Shunsuke, MD, Sakamoto, Koji, MD, PhD, Wakai, Kenji, MD, PhD, Yokoi, Kohei, MD, PhD, Hasegawa, Yoshinori, MD, PhD

“…Background There is only limited information on the clinical impact of combined pulmonary fibrosis and emphysema (CPFE) on postoperative and survival outcomes…”
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Breast cancer S1P is associated with pSphK1 and lymphatic metastasis by Tsuchida, Junko, MD, Nagahashi, Masayuki, MD, PhD, Nakajima, Masato, MD, PhD, Moro, Kazuki, MD, Tatsuda, Kumiko, MD, Ramanathan, Rajesh, MD, Takabe, Kazuaki, MD, PhD, FACS, Wakai, Toshifumi, MD, PhD, FACS

“…Abstract Background Sphingosine-1-phosphate (S1P), a pleiotropic bioactive lipid mediator, has been implicated as a key regulatory molecule in cancer through…”
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Alteration of the DNA damage response in colorectal tumor progression by Takabayashi, Hiroaki, MD, Wakai, Toshifumi, MD, PhD, Ajioka, Yoichi, MD, PhD, Korita, Pavel V., MD, PhD, Yamaguchi, Naoyuki, BS

“…Summary Recent studies have demonstrated increased levels of DNA double-strand breaks (DSBs) and activation of the DNA damage response (DDR) in precancerous…”
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Prognostic analysis of submucosa-invasive gastric cancer with lymph node metastasis by Hanyu, Takaaki, MD, PhD, Matsuki, Atsushi, MD, PhD, Kosugi, Shin-ichi, MD, PhD, Ishikawa, Takashi, MD, PhD, Nashimoto, Atsushi, MD, PhD, Yabusaki, Hiroshi, MD, PhD, Aizawa, Masaki, MD, PhD, Ichikawa, Hiroshi, MD, PhD, Shimada, Yoshifumi, MD, PhD, Hirose, Yuki, MD, Wakai, Toshifumi, MD, PhD

“…Background The aims of this study were to identify prognostic factors of patients with submucosa-invasive (T1b) gastric cancer and to verify the validity of…”
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Association between non-sentinel lymph node metastasis and clinicopathological factors in sentinel lymph node metastasis positive breast cancer by Koyama, Yu, MD, PhD, Hasegawa, Miki, MD, Tatsuda, Kumiko, MD, Sakata, Jun, MD, Kobayashi, Takashi, Minagawa, Masahiro, MD, Kosugi, Shin-Ichi, MD, PhD, Wakai, Toshifumi, MD, PhD

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