Search Results - "Waitman, Karoline B."

1,3-Diphenylureido hydroxamate as a promising scaffold for generation of potent antimalarial histone deacetylase inhibitors by Tavares, Maurício T., Krüger, Arne, Yan, Sun L. Rei, Waitman, Karoline B., Gomes, Vinícius M., de Oliveira, Daffiny Sumam, Paz, Franciarli, Hilscher, Sebastian, Schutkowski, Mike, Sippl, Wolfgang, Ruiz, Claudia, Toledo, Mônica F. Z. J., Hassimotto, Neuza M. A., Machado-Neto, João A., Poso, Antti, Cameron, Michael D., Bannister, Thomas D., Palmisano, Giuseppe, Wrenger, Carsten, Kronenberger, Thales, Parise-Filho, Roberto

“…We report a series of 1,3-diphenylureido hydroxamate HDAC inhibitors evaluated against sensitive and drug-resistant P. falciparum strains. Compounds 8a–d show…”
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Design, synthesis, and evaluation of Bothrops venom serine protease peptidic inhibitors by da Silva, Gloria Maria, de Souza, Daniel Henrique Berto, Waitman, Karoline B, Ebram, Matteo Celano, Fessel, Melissa R, Zainescu, Iuliu Cezar, Portaro, Fernanda C, Heras, Montse, de Andrade, Sonia A

“…In Central and South America, snakebite envenomation is mainly caused by spp. snakes, whose venoms feature significant biochemical richness, including serine…”
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HDAC specificity and kinase off-targeting by purine-benzohydroxamate anti-hematological tumor agents by Waitman, Karoline B, de Almeida, Larissa C, Primi, Marina C, Carlos, Jorge A E G, Ruiz, Claudia, Kronenberger, Thales, Laufer, Stefan, Goettert, Marcia Ines, Poso, Antti, Vassiliades, Sandra V, de Souza, Vinícius A M, Toledo, Mônica F Z J, Hassimotto, Neuza M A, Cameron, Michael D, Bannister, Thomas D, Costa-Lotufo, Letícia V, Machado-Neto, João A, Tavares, Maurício T, Parise-Filho, Roberto

“…A series of hybrid inhibitors, combining pharmacophores of known kinase inhibitors bearing anilino-purines (ruxolitinib, ibrutinib) and benzohydroxamate HDAC…”
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