Search Results - "Waite, Roger L"

Neuro-psychopharmacogenetics and Neurological Antecedents of Posttraumatic Stress Disorder: Unlocking the Mysteries of Resilience and Vulnerability by Bowirrat, Abdalla, Chen, Thomas J H, Blum, Kenneth, Madigan, Margaret, Bailey, John A, Chuan Chen, Amanda Lih, Downs, B William, Braverman, Eric R, Radi, Shahien, Waite, Roger L, Kerner, Mallory, Giordano, John, Morse, Siohban, Oscar-Berman, Marlene, Gold, Mark

“…Background and Hypothesis: Although the biological underpinnings of immediate and protracted traumarelated responses are extremely complex, 40 years of…”
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Neurogenetics of Dopaminergic Receptor Supersensitivity in Activation of Brain Reward Circuitry and Relapse: Proposing "Deprivation-Amplification Relapse Therapy" (DART) by Blum, Kenneth, Chen, Thomas J.H., Downs, B. William, Bowirrat, Abdalla, Waite, Roger L., Braverman, Eric R., Madigan, Margaret, Oscar-Berman, Marlene, DiNubile, Nicholas, Stice, Eric, Giordano, John, Morse, Siobhan, Gold, Mark

“…Background and Hypothesis: It is well known that after prolonged abstinence, individuals who use their drug of choice experience a powerful euphoria that often…”
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Activation instead of blocking mesolimbic dopaminergic reward circuitry is a preferred modality in the long term treatment of reward deficiency syndrome (RDS): a commentary by Blum, Kenneth, Chen, Amanda Lih Chuan, Chen, Thomas J H, Braverman, Eric R, Reinking, Jeffrey, Blum, Seth H, Cassel, Kimberly, Downs, Bernard W, Waite, Roger L, Williams, Lonna, Prihoda, Thomas J, Kerner, Mallory M, Palomo, Tomas, Comings, David E, Tung, Howard, Rhoades, Patrick, Oscar-Berman, Marlene

“…Based on neurochemical and genetic evidence, we suggest that both prevention and treatment of multiple addictions, such as dependence to alcohol, nicotine and…”
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Repetitive H-wave device stimulation and program induces significant increases in the range of motion of post operative rotator cuff reconstruction in a double-blinded randomized placebo controlled human study by Blum, Kenneth, Chen, Amanda L C, Chen, Thomas J H, Waite, Roger L, Downs, B William, Braverman, Eric R, Kerner, Mallory M, Savarimuthu, Stella M, DiNubile, Nicholas

“…Albeit other prospective randomized controlled clinical trials on H-Wave device stimulation (HWDS), this is the first randomized double-blind placebo…”
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Preliminary investigation of plasma levels of sex hormones and human growth factor(s), and P300 latency as correlates to cognitive decline as a function of gender by Braverman, Eric R, Chen, Thomas J H, Chen, Amanda L C, Kerner, Mallory M, Tung, Howard, Waite, Roger L, Schoolfield, John, Blum, Kenneth

“…Aging is marked by declines in levels of many sex hormones and growth factors, as well as in cognitive function. The P300 event-related potential has been…”
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Attention-deficit-hyperactivity disorder and reward deficiency syndrome by Blum, Kenneth, Chen, Amanda Lih-Chuan, Braverman, Eric R, Comings, David E, Chen, Thomas J H, Arcuri, Vanessa, Blum, Seth H, Downs, Bernard W, Waite, Roger L, Notaro, Alison, Lubar, Joel, Williams, Lonna, Prihoda, Thomas J, Palomo, Tomas, Oscar-Berman, Marlene

“…Molecular genetic studies have identified several genes that may mediate susceptibility to attention deficit hyperactivity disorder (ADHD). A consensus of the…”
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Generational association studies of dopaminergic genes in reward deficiency syndrome (RDS) subjects: selecting appropriate phenotypes for reward dependence behaviors by Blum, Kenneth, Chen, Amanda L C, Oscar-Berman, Marlene, Chen, Thomas J H, Lubar, Joel, White, Nancy, Lubar, Judith, Bowirrat, Abdalla, Braverman, Eric, Schoolfield, John, Waite, Roger L, Downs, Bernard W, Madigan, Margaret, Comings, David E, Davis, Caroline, Kerner, Mallory M, Knopf, Jennifer, Palomo, Tomas, Giordano, John J, Morse, Siobhan A, Fornari, Frank, Barh, Debmalya, Femino, John, Bailey, John A

“…Abnormal behaviors involving dopaminergic gene polymorphisms often reflect an insufficiency of usual feelings of satisfaction, or Reward Deficiency Syndrome…”
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Do dopaminergic gene polymorphisms affect mesolimbic reward activation of music listening response? Therapeutic impact on Reward Deficiency Syndrome (RDS) by Blum, Kenneth, Chen, Thomas J.H, Chen, Amanda L.H, Madigan, Margaret, Downs, B. William, Waite, Roger L, Braverman, Eric R, Kerner, Mallory, Bowirrat, Abdalla, Giordano, John, Henshaw, Harry, Gold, Mark S

“…Summary Using fMRI, Menon and Levitin [9] clearly found for the first time that listening to music strongly modulates activity in a network of mesolimbic…”
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Neuropsychopharmacology and Neurogenetic Aspects of Executive Functioning: Should Reward Gene Polymorphisms Constitute a Diagnostic Tool to Identify Individuals at Risk for Impaired Judgment? by Bowirrat, Abdalla, Chen, Thomas J. H., Oscar-Berman, Marlene, Madigan, Margaret, Chen, Amanda LH, Bailey, John A., Braverman, Eric R., Kerner, Mallory, Giordano, John, Morse, Siobhan, Downs, B. William, Waite, Roger L., Fornari, Frank, Armaly, Zaher, Blum, Kenneth

“…Executive functions are processes that act in harmony to control behaviors necessary for maintaining focus and achieving outcomes. Executive dysfunction in…”
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Overcoming qEEG Abnormalities and Reward Gene Deficits during Protracted Abstinence in Male Psychostimulant and Polydrug Abusers Utilizing Putative Dopamine D2 Agonist Therapy: Part 2 by Blum, Kenneth, Chen, Thomas J. H., Morse, Siobhan, Giordano, John, Chen, Amanda Lih Chaun, Thompson, James, Allen, Cameron, Smolen, Andrew, Lubar, Joel, Stice, Eric, Downs, B. William, Waite, Roger L., Madigan, Margaret A., Kerner, Mallory, Fornari, Frank, Braverman, Eric R.

“…Background: It is well established that in both food- and drug-addicted individuals there is "dopamine resistance" associated with the DRD2 gene A1 allele…”
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H-Wave® induces arteriolar vasodilation in rat striated muscle via nitric oxide-mediated mechanisms by Smith, Thomas L., Blum, Kenneth, Callahan, Michael F., DiNubile, Nicholas A., Chen, Thomas J.H., Waite, Roger L.

“…H‐Wave® electrical device stimulation (HWDS) is used clinically to expedite recovery from soft tissue injuries. We hypothesized that HWDS induces arteriolar…”
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Early Intervention of Intravenous KB220IV- Neuroadaptagen Amino-Acid Therapy (NAAT)™ Improves Behavioral Outcomes in a Residential Addiction Treatment Program: A Pilot Study by Miller, Merlene, Chen, Amanda LC, Stokes, Stan D., Silverman, Susan, Bowirrat, Abdalla, Manka, Matthew, Manka, Debra, Miller, David K., Perrine, Kenneth, Chen, Thomas JH, Bailey, John A., Downs, William, Waite, Roger L., Madigan, Margaret A., Braverman, Eric R., Damle, Uma, Kerner, Mallory, Giordano, John, Morse, Siobhan, Oscar-Berman, Marlene, Barh, Debmalya, Blum, Kenneth

“…Substance use disorders (SUD) are inheritable and the culprit is hypodopaminergic function regulated by reward genes. We evaluated a natural dopaminergic…”
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Neurogenetics and Clinical Evidence for the Putative Activation of the Brain Reward Circuitry by a Neuroadaptagen: Proposing an Addiction Candidate Gene Panel Map by Chen, Thomas J.H., Blum, Kenneth, Chen, Amanda L.C., Bowirrat, Abdalla, Downs, William B., Madigan, Margret A., Waite, Roger L., Bailey, John A., Kerner, Mallory, Yeldandi, Swetha, Majmundar, Neil, Giordano, John, Morse, Siohban, Miller, David, Fornari, Frank, Braverman, Eric R.

“…This document presents evidence supporting the role of the KB220/KB220Z neuroadaptagens consisting of amino-acid neurotransmitter precursors and…”
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LG839: Anti-obesity effects and polymorphic gene correlates of reward deficiency syndrome by Blum, Kenneth, Chen, Amanda L. C., Chen, Thomas J. H., Rhoades, Patrick, Prihoda, Thomas J., Downs, B. William, Waite, Roger L., Williams, Lonna, Braverman, Eric R., Braverman, Dasha, Arcuri, Vanessa, Kerner, Mallory, Blum, Seth H., Palomo, Tomas

“…Introduction This study systematically assessed the weight management effects of a novel experimental DNA-customized nutraceutical, LG839 (LifeGen®, Inc., La…”
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Manipulation of catechol- O -methyl-transferase (COMT) activity to influence the attenuation of substance seeking behavior, a subtype of Reward Deficiency Syndrome (RDS), is dependent upon gene polymorphisms: A hypothesis by Blum, Kenneth, Chen, Thomas J.H, Meshkin, Brian, Waite, Roger L, Downs, B. William, Blum, Seth H, Mengucci, Julie F, Arcuri, Vanessa, Braverman, Eric R, Palomo, Tomas

“…Summary There are common genetic mechanisms responsible for both drug effects and subsequent seeking behavior. In 1996, we coined the term Reward Deficiency…”
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Nutrigenomic targeting of carbohydrate craving behavior: Can we manage obesity and aberrant craving behaviors with neurochemical pathway manipulation by Immunological Compatible Substances (nutrients) using a Genetic Positioning System (GPS) Map? by Downs, B. William, Chen, Amanda L.C, Chen, Thomas J.H, Waite, Roger L, Braverman, Eric R, Kerner, Mallory, Braverman, Dasha, Rhoades, Patrick, Prihoda, Thomas J, Palomo, Tomas, Oscar-Berman, Marlene, Reinking, Jeffrey, Blum, Seth H, DiNubile, Nicholas A, Liu, H.H, Blum, Kenneth

“…Summary Genetic mediated physiological processes that rely on both pharmacological and nutritional principles hold great promise for the successful therapeutic…”
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Hypothesizing repetitive paraphilia behavior of a medication refractive Tourette’s syndrome patient having rapid clinical attenuation with KB220Z-nutrigenomic amino-acid therapy (NAAT) by Mclaughlin, Thomas, Oscar-Berman, Marlene, Simpatico, Thomas, Giordano, John, Jones, Scot, Barh, Debmayla, Downs, William B, Waite, Roger L, Madigan, Margaret, Dushaj, Kristina, Lohmann, Raquel, Braverman, Eric R, Han, David, Blum, Kenneth

“…Many patients presenting multiple behaviors including drug and food abuse as well as other pathological repetitive unwanted activities such as gambling,…”
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Hypothesizing that brain reward circuitry genes are genetic antecedents of pain sensitivity and critical diagnostic and pharmacogenomic treatment targets for chronic pain conditions by Chen, Amanda L.-C, Chen, Thomas J.H, Waite, Roger L, Reinking, Jeffrey, Tung, Howard L, Rhoades, Patrick, Downs, B. William, Braverman, Eric, Braverman, Dasha, Kerner, Mallory, Blum, Seth H, DiNubile, Nicholas, Smith, David, Oscar-Berman, Marlene, Prihoda, Thomas J, Floyd, John B, O’Brien, David, Liu, H.H, Blum, Kenneth

“…Summary While it is well established that the principal ascending pathways for pain originate in the dorsal horn of the spinal cord and in the medulla, the…”
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Test of variables of attention (TOVA) as a predictor of early attention complaints, an antecedent to dementia by Braverman, Eric R, Chen, Amanda Lih-Chuan, Chen, Thomas J H, Schoolfield, John D, Notaro, Alison, Braverman, Dasha, Kerner, Mallory, Blum, Seth H, Arcuri, Vanessa, Varshavskiy, Michael, Damle, Uma, Downs, B William, Waite, Roger L, Oscar-Berman, Marlene, Giordano, John, Blum, Kenneth

“…The goal of this study was to determine if impairments detected by the test of variables of attention (TOVA) may be used to predict early attention complaints…”
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H-Wave® effects on blood flow and angiogenesis in longitudinal studies in rats by Smith, Thomas L, Callahan, Michael F, Blum, Kenneth, Dinubile, Nicholas A, Chen, Thomas J H, Waite, Roger L

“…Effects of repeated H-Wave® device stimulation (HWDS) on blood flow and angiogenesis in the rat hind limb were studied. The hypothesis tested was that HWDS…”
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