Search Results - "Wainwright, N"

Epigenetics and Cancer Stem Cells: Unleashing, Hijacking, and Restricting Cellular Plasticity by Wainwright, Elanor N, Scaffidi, Paola

“…Epigenetic mechanisms have emerged as key players in cancer development which affect cellular states at multiple stages of the disease. During carcinogenesis,…”
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Magmatic thickening of crust in non–plate tectonic settings initiated the subaerial rise of Earth’s first continents 3.3 to 3.2 billion years ago by Chowdhury, Priyadarshi, Mulder, Jacob A., Cawood, Peter A., Bhattacharjee, Surjyendu, Roy, Subhajit, Wainwright, Ashlea N., Nebel, Oliver, Mukherjee, Subham

“…When and how Earth's earliest continents—the cratons—first emerged above the oceans (i.e., emersion) remain uncertain. Here, we analyze a craton-wide record of…”
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Crustal rejuvenation stabilised Earth’s first cratons by Mulder, Jacob A., Nebel, Oliver, Gardiner, Nicholas J., Cawood, Peter A., Wainwright, Ashlea N., Ivanic, Timothy J.

“…The formation of stable, evolved (silica-rich) crust was essential in constructing Earth’s first cratons, the ancient nuclei of continents. Eoarchaean…”
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The ‘Real Welfare’ scheme: benchmarking welfare outcomes for commercially farmed pigs by Pandolfi, F., Stoddart, K., Wainwright, N., Kyriazakis, I., Edwards, S. A.

“…Animal welfare standards have been incorporated in EU legislation and in farm assurance schemes, based on scientific information and aiming to safeguard the…”
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Interventions targeting motor skills in pre-school-aged children with direct or indirect parent engagement: a systematic review and narrative synthesis by Stevenson, A., Wainwright, N., Williams, A.

“…Competency in fundamental movement skills (FMS) lays the foundation for developing more complex motor skills and supporting a physically active future…”
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Evaluation of a training programme for critical incident debrief facilitators by Johnson, J, Pointon, L, Keyworth, C, Wainwright, N, Moores, L, Bates, J, Hinsby, K

“…Abstract Background Critical incident debriefs are a commonly used occupational health tool for supporting staff after traumatic work incidents. However, there…”
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Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis by Morales Torres, Cristina, Wu, Mary Y., Hobor, Sebastijan, Wainwright, Elanor N., Martin, Matthew J., Patel, Harshil, Grey, William, Grönroos, Eva, Howell, Steven, Carvalho, Joana, Snijders, Ambrosius P., Bustin, Michael, Bonnet, Dominique, Smith, Paul D., Swanton, Charles, Howell, Michael, Scaffidi, Paola

“…Continuous cancer growth is driven by subsets of self-renewing malignant cells. Targeting of uncontrolled self-renewal through inhibition of stem cell-related…”
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ROBO2 restricts the nephrogenic field and regulates Wolffian duct–nephrogenic cord separation by Wainwright, Elanor N., Wilhelm, Dagmar, Combes, Alexander N., Little, Melissa H., Koopman, Peter

“…ROBO2 plays a key role in regulating ureteric bud (UB) formation in the embryo, with mutations in humans and mice leading to supernumerary kidneys. Previous…”
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A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells by Tallack, Michael R, Whitington, Tom, Yuen, Wai Shan, Wainwright, Elanor N, Keys, Janelle R, Gardiner, Brooke B, Nourbakhsh, Ehsan, Cloonan, Nicole, Grimmond, Sean M, Bailey, Timothy L, Perkins, Andrew C

“…KLF1 regulates a diverse suite of genes to direct erythroid cell differentiation from bipotent progenitors. To determine the local cis-regulatory contexts and…”
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Psychological distress, major depressive disorder, and risk of stroke by SURTEES, P. G, WAINWRIGHT, N. W. J, LUBEN, R. N, WAREHAM, N. J, BINGHAM, S. A, KHAW, K.-T

“…Studies have suggested that mood status is associated with an increased risk of stroke, though mostly based on measures of depression defined by symptoms alone…”
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The “Real Welfare” scheme: Identification of risk and protective factors for welfare outcomes in commercial pig farms in the UK by Pandolfi, F., Kyriazakis, I., Stoddart, K., Wainwright, N., Edwards, S.A.

“…•The “Real Welfare” protocol assessed 112,241 finisher pens from 1928 farms.•Five main animal-based welfare outcomes were considered.•Common and specific risk…”
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Psychosocial factors and incident asthma hospital admissions in the EPIC‐Norfolk cohort study by Wainwright, N. W. J., Surtees, P. G., Wareham, N. J., Harrison, B. D. W.

“…Background:  Case series and case‐control studies have shown high rates of psychosocial and behavioural risk factors amongst patients admitted to hospital with…”
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Places, people, and their physical and mental functional health by Wainwright, N W J, Surtees, P G

“…Study objective: To investigate the impact of area of residence on functional health as represented by medical outcomes study SF-36 physical and mental…”
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The association between social stress and global cognitive function in a population-based study: the European Prospective Investigation into Cancer (EPIC)-Norfolk study by Leng, Y, Wainwright, N W J, Hayat, S, Stephan, B C M, Matthews, F E, Luben, R, Surtees, P G, Khaw, K-T, Brayne, C

“…Stress is thought to exert both positive and negative effects on cognition, but the precise cognitive effects of social stress and individuals' response to…”
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Measuring the shielding properties of flexible or rigid enclosures for portable electronics by Duffy, A. P., Arihilam, E., Sasse, Hugh, Parker, Sarah, Armstrong, R., Wainwright, N., Steggles, S., Thomas, T.

“…Heaviside, in volume 1 of Electromagnetic theory, considered shielding of conducting materials in the form of attenuation. This treatment is still significant…”
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Rapid screening of gene function by systemic delivery of morpholino oligonucleotides to live mouse embryos by McClelland, Kathryn S, Wainwright, Elanor N, Bowles, Josephine, Koopman, Peter

“…Traditional gene targeting methods in mice are complex and time consuming, especially when conditional deletion methods are required. Here, we describe a novel…”
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The Foundation Phase in Wales - a play-based curriculum that supports the development of physical literacy by Wainwright, N., Goodway, J., Whitehed, M., Williams, A., Kirk, D.

“…In 2008, the Welsh Assembly Government began the implementation of a new holistic play-based learning continuum for children aged three to seven called the…”
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Generalized anxiety disorder and excess cancer deaths: findings from a large, longitudinal study by Remes, O, Wainwright, N, Surtees, P, Lafortune, L, Khaw, K.T, Brayne, C

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Sense of coherence, lifestyle choices and mortality by Wainwright, N W J, Surtees, P G, Welch, A A, Luben, R N, Khaw, K-T, Bingham, S A

“…Background:Based on data from the European Prospective Investigation into Cancer, Norfolk (EPIC-Norfolk) study, we have previously shown a strong sense of…”
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Paper 5: How can we assess physical literacy? by Barnett, L., Dudley, D., Telford, R., Lubans, D., Bryant, A., Roberts, W., Morgan, P., Schranz, N., Weissensteiner, J., Vella, S., Salmon, J., Ziviani, J., Okely, A., Wainwright, N., Roberts, J., Keegan, R.

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