Search Results - "Wailemann, Rosângela A."

TGF-β1 modulates the homeostasis between MMPs and MMP inhibitors through p38 MAPK and ERK1/2 in highly invasive breast cancer cells by Gomes, Luciana R, Terra, Letícia F, Wailemann, Rosângela Am, Labriola, Leticia, Sogayar, Mari C

“…Metastasis is the main factor responsible for death in breast cancer patients. Matrix metalloproteinases (MMPs) and their inhibitors, known as tissue…”
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The antiproliferative effect of FGF2 in K-Ras-driven tumor cells involves modulation of rRNA and the nucleolus by de Luna Vitorino, Francisca N, Levy, Michaella J, Mansano Wailemann, Rosangela A, Lopes, Mariana, Silva, Mariana Loterio, Sardiu, Mihaela E, Garcia, Benjamin A, Machado Motta, Maria Cristina, Oliveira, Carla Columbano, Armelin, Hugo Aguirre, Florens, Laurence A, Washburn, Michael P, Pinheiro Chagas da Cunha, Julia

“…The nucleolus is sensitive to stress and can orchestrate a chain of cellular events in response to stress signals. Despite being a growth factor, FGF2 has…”
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Distinct photo-oxidation-induced cell death pathways lead to selective killing of human breast cancer cells by Dos Santos, Ancély F., Inague, Alex, Arini, Gabriel S., Terra, Letícia F., Wailemann, Rosangela A. M., Pimentel, André C., Yoshinaga, Marcos Y., Silva, Ricardo R., Severino, Divinomar, de Almeida, Daria Raquel Q., Gomes, Vinícius M., Bruni-Cardoso, Alexandre, Terra, Walter R., Miyamoto, Sayuri, Baptista, Maurício S., Labriola, Leticia

“…Lack of effective treatments for aggressive breast cancer is still a major global health problem. We have previously reported that photodynamic therapy using…”
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Fluence Rate Determines PDT Efficiency in Breast Cancer Cells Displaying Different GSH Levels by Santos, Ancély F., Almeida, Daria Raquel Q., Terra, Letícia F., Wailemann, Rosangela A.M., Gomes, Vinícius M., Arini, Gabriel S., Ravagnani, Felipe G., Baptista, Maurício S., Labriola, Leticia

“…Photodynamic therapy (PDT) appears as a promising alternative in the treatment of breast cancer since it can be highly effective in curing cancer while…”
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HSPB1 Is Essential for Inducing Resistance to Proteotoxic Stress in Beta-Cells by Gomes, Vinícius M., Wailemann, Rosangela A. M., Arini, Gabriel S., Oliveira, Talita C., Almeida, Daria R. Q., dos Santos, Ancély F., Terra, Letícia F., Lortz, Stephan, Labriola, Leticia

“…During type 1 diabetes mellitus (T1DM) development, beta-cells undergo intense endoplasmic reticulum (ER) stress that could result in apoptosis through the…”
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Methylene blue photodynamic therapy induces selective and massive cell death in human breast cancer cells by Dos Santos, Ancély F, Terra, Letícia F, Wailemann, Rosangela A M, Oliveira, Talita C, Gomes, Vinícius de Morais, Mineiro, Marcela Franco, Meotti, Flávia Carla, Bruni-Cardoso, Alexandre, Baptista, Maurício S, Labriola, Leticia

“…Breast cancer is the main cause of mortality among women. The disease presents high recurrence mainly due to incomplete efficacy of primary treatment in…”
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Proteins differentially expressed in human beta-cells-enriched pancreatic islet cultures and human insulinomas by Terra, Letícia F., Teixeira, Priscila C., Wailemann, Rosangela A.M., Zelanis, André, Palmisano, Giuseppe, Cunha-Neto, Edecio, Kalil, Jorge, Larsen, Martin R., Labriola, Leticia, Sogayar, Mari C.

“…[Display omitted] •Comparison of protein profiles of human pancreatic islets and insulinomas.•We identified proteins never described neither in human…”
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HSPB1 influences mitochondrial respiration in ER-stressed beta cells by Mule, Simon Ngao, Gomes, Vinícius De Morais, Wailemann, Rosangela A.M., Macedo-da-Silva, Janaina, Rosa-Fernandes, Livia, Larsen, Martin R., Labriola, Letícia, Palmisano, Giuseppe

“…Beta-cell death and dysfunction are involved in the development of type 1 and 2 diabetes. ER-stress impairs beta-cells function resulting in pro-apoptotic…”
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Heat shock protein B1 is a key mediator of prolactin-induced beta-cell cytoprotection against oxidative stress by Terra, Letícia F., Wailemann, Rosangela A.M., dos Santos, Ancély F., Gomes, Vinicius M., Silva, Railmara P., Laporte, Anna, Meotti, Flávia C., Terra, Walter R., Palmisano, Giuseppe, Lortz, Stephan, Labriola, Leticia

“…Maintaining islet cell viability in vitro, although challenging, appears to be a strategy for improving the outcome of pancreatic islet transplantation. We…”
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Paradoxical Activation of Oncogenic Signaling as a Cancer Treatment Strategy by Dias, Matheus Henrique, Friskes, Anoek, Wang, Siying, Fernandes Neto, Joao M, van Gemert, Frank, Mourragui, Soufiane, Papagianni, Chrysa, Kuiken, Hendrik J, Mainardi, Sara, Alvarez-Villanueva, Daniel, Lieftink, Cor, Morris, Ben, Dekker, Anna, van Dijk, Emma, Wilms, Lieke H S, da Silva, Marcelo S, Jansen, Robin A, Mulero-Sánchez, Antonio, Malzer, Elke, Vidal, August, Santos, Cristina, Salazar, Ramón, Wailemann, Rosangela A M, Torres, Thompson E P, De Conti, Giulia, Raaijmakers, Jonne A, Snaebjornsson, Petur, Yuan, Shengxian, Qin, Wenxin, Kovach, John S, Armelin, Hugo A, Te Riele, Hein, van Oudenaarden, Alexander, Jin, Haojie, Beijersbergen, Roderick L, Villanueva, Alberto, Medema, Rene H, Bernards, Rene

“…Cancer homeostasis depends on a balance between activated oncogenic pathways driving tumorigenesis and engagement of stress response programs that counteract…”
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Necroptosis activation is associated with greater methylene blue-photodynamic therapy-induced cytotoxicity in human pancreatic ductal adenocarcinoma cells by de Almeida, Daria R Q, Dos Santos, Ancély F, Wailemann, Rosangela A M, Terra, Letícia F, Gomes, Vinícius M, Arini, Gabriel S, Bertoldi, Ester R M, Reis, Eduardo M, Baptista, Maurício S, Labriola, Leticia

“…Pancreatic ductal adenocarcinomas (PDAC) are the fourth leading cause of death due to neoplasms. In view of the urgent need of effective treatments for PDAC,…”
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Heat shock protein B1 is required for the prolactin-induced cytoprotective effects on pancreatic islets by Wailemann, Rosangela AM, Terra, Letícia F., Oliveira, Talita C., Dos Santos, Ancély F., Gomes, Vinícius M., Labriola, Leticia

“…The success of islet transplantation has improved lately. Unfortunately, it is still compromised by cell loss. We have shown that prolactin (PRL) inhibits…”
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Abstract 5266: TGF-β1 modulates the homeostasis between MMPs and MMPs inhibitors through p38 MAPK and ERK½ in highly invasive human breast cancer cells by Gomes, Luciana R., Terra, Letícia F., Wailemann, Rosângela A., Labriola, Leticia, Sogayar, Mari C.

“…Matrix metalloproteinases (MMPs) and their specific inhibitors, known as tissue inhibitors of MMPs (TIMPs) and the membrane-associated MMP inhibitor (RECK),…”
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TGF-[beta]1 modulates the homeostasis between MMPs and MMP inhibitors through p38 MAPK and ERK1/2 in highly invasive breast cancer cells by Gomes, Luciana R, Terra, Letícia F, Wailemann, Rosângela AM, Labriola, Leticia, Sogayar, Mari C

“…BackgroundMetastasis is the main factor responsible for death in breast cancer patients. Matrix metalloproteinases (MMPs) and their inhibitors, known as tissue…”
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HSP25/27 Plays a Key Function in Prolactin-Induced Cytoprotective Effects on Beta-Cells by Wailemann, Rosangela A M, Terra, Leticia F, Oliveira, Talita C, Santos, Ancely F, Sogayar, Mari C, Labriola, Leticia

“…Transplantation of pancreatic islets isolated from organ donors constitutes a promising alternative treatment for type1 diabetes, however, it is severely…”
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Abstract 508: Development of a human model to study the role of Glypican-3 (GPC3) on tumor progression of the mammary gland by Castillo, Lilian F., Tascon, Rocio, Lago Huvelle1, Amparo María, Ferreira dos Santos, Ancély, Ferreira Terra, Letícia, Wailemann, Rosangela A. m., Oliveira, Talita C., Sogayar, Mari, Labriola, Leticia, Bal de Kier Joffe, Elisa, Peters, Maria Giselle

“…GPC3 was proposed as a negative regulator of cell proliferation in the mammary gland. Whereas normal breast tissues present high GPC3 levels, its expression is…”
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