Search Results - "Waidha, Kamran"

Analysis of Inhibition Potential of Nimbin and its Analogs against NF-κB Subunits p50 and p65: A Molecular Docking and Molecular Dynamics Study by Khan, Asiya, Singh, Divyam, Waidha, Kamran, Sisodiya, Sandeep, Gopinath, Pushparathinam, Hussian, Showket, Tanwar, Pranay, Katare, Deepshikha Pande

“…Cancer remains the major cause of morbidity and mortality. The nuclear factor kappa-B (NF- κB) plays an indispensable role in cancer cell proliferation and…”
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Inhibition of Cysteine Proteases by 6,6′-Dihydroxythiobinupharidine (DTBN) from Nuphar lutea by Waidha, Kamran, Zurgil, Udi, Ben-Zeev, Efrat, Gopas, Jacob, Rajendran, Saravanakumar, Golan-Goldhirsh, Avi

“…The specificity of inhibition by 6,6′-dihydroxythiobinupharidine (DTBN) on cysteine proteases was demonstrated in this work. There were differences in the…”
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6,6′-Dihydroxythiobinupharidine (DTBN) Purified from Nuphar lutea Leaves Is an Inhibitor of Protein Kinase C Catalytic Activity by Waidha, Kamran, Anto, Nikhil Ponnoor, Jayaram, Divya Ram, Golan-Goldhirsh, Avi, Rajendran, Saravanakumar, Livneh, Etta, Gopas, Jacob

“…Water lily (Nuphar) bioactive extracts have been widely used in traditional medicine owing to their multiple applications against human ailments. Phyto-active…”
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In Vitro and In Vivo Therapeutic Potential of 6,6'-Dihydroxythiobinupharidine (DTBN) from Nuphar lutea on Cells and K18- hACE2 Mice Infected with SARS-CoV-2 by Weiss, Shay, Waidha, Kamran, Rajendran, Saravanakumar, Benharroch, Daniel, Khalilia, Jannat, Levy, Haim, Bar-David, Elad, Golan-Goldhirsh, Avi, Gopas, Jacob, Ben-Shmuel, Amir

“…We have previously published research on the anti-viral properties of an alkaloid mixture extracted from , the major components of the partially purified…”
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Design and identification of novel annomontine analogues against SARS-CoV-2: An in-silico approach by Waidha, Kamran, Saxena, Anjali, Kumar, Prashant, Sharma, Sunil, Ray, Devalina, Saha, Biswajit

“…COVID-19 has currently emerged as the major global pandemic affecting the lives of people across the globe. It broke out from Wuhan Province of China, first…”
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Effect of dietary supplementation of microalgae Spirulina and Chlorella on growth performance and blood profile of broiler chicken at high altitude by SWATI, WAIDHA, KAMRAN, NEGAM, SUBANGGI, PARVEEN, NAZIA, CHUSKIT, DEACHAN, K, MAYARNGAM, CHAURASIA, O P

“…The objective of this study was to explore the effect of Spirulina and Chlorella as a dietary supplement on thegrowth performance of broiler chicken at high…”
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Cardiovascular diseases display etiological and seasonal trend in human population: Evidence from seasonal cardiovascular comorbid diseases (SCCD) index by Patel, Jai Chand, Gupta, Apoorv, Kumar, Prince, Waidha, Kamran Manzoor, Deep, Aakash, Kumar, Ashish, Katare, Deepshikha Pande, Sharma, Arun K.

“…Seasonal changes in the human cardiovascular system are known to play an important role in the onset of many diseases. Confounding variables include behavioral…”
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Effect of impaired autophagic flux on breast carcinogenesis through the enhanced LC3-p62-NRF2 feedback loop by Aftab, Mehreen, Waidha, Kamran, Gopas, Jacob, Hussain, Showket

“…6 Background: Breast cancer affects more women worldwide than any other type of cancer. Although some genes have been identified as potential causes, the exact…”
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In-silico investigations of selective miRNA-gene targets and their validation studies in obstructive sleep apnea (OSA) patient cohorts by Khurana, Sartaj, Waidha, Kamran, Guleria, Randeep, Sharda, Shivani, Bose, Sudeep

“…This model represents the profiling of miR-27 and let-7 and their targets in PBMC’s derived from patients with obstructive sleep apnea. [Display omitted]…”
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β-1,3-glucan from Euglena gracilis : a promising epidrug targeting epigenetic regulators PRMTs and SIRTs for therapeutic applications in ovarian cancer by Palol, Varsha Virendra, Waidha, Kamran, Moovarkumudalvan, Balasubramanian, Valavath Baburajan, Navya, Saravanan, Suresh Kumar, Lakshmanan, Divya, Subramanyam, Veni, Chinnadurai, Raj Kumar

“…Natural products serve as a valuable resource in drug discovery and the identification of bioactive molecules in the field of epimedicine, which targets…”
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In Vitro and In Vivo Therapeutic Potential of 6,6′-Dihydroxythiobinupharidine from INuphar lutea/I on Cells and K18-IhACE2/I Mice Infected with SARS-CoV-2 by Weiss, Shay, Waidha, Kamran, Rajendran, Saravanakumar, Benharroch, Daniel, Khalilia, Jannat, Levy, Haim, Bar-David, Elad, Golan-Goldhirsh, Avi, Gopas, Jacob, Ben-Shmuel, Amir

“…We have previously published research on the anti-viral properties of an alkaloid mixture extracted from Nuphar lutea, the major components of the partially…”
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Design, synthesis and identification of novel coumaperine derivatives for inhibition of human 5-LOX: Antioxidant, pseudoperoxidase and docking studies by Muthuraman, Subramani, Sinha, Shweta, Vasavi, C.S., Waidha, Kamran Manzoor, Basu, Biswarup, Munussami, Punnagai, Balamurali, M.M., Doble, Mukesh, Saravana Kumar, Rajendran

“…Pepper based compounds developed as potent 5-LOX inhibitors. Coumaperine derivatives substituted with multiple methoxy and hydroxyl groups exhibited high 5-LOX…”
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Pyrrole‐Fused Benzoxazinones/Quinoxalinones: Molecular Dynamic Simulation, Antiproliferative and Antibacterial Activities by Selvendran, Suresh, Das, Souvik, Waidha, Kamran, Venkatesan, Swathi, Balamurali, M. M., Basu, Biswarup, Rajendran, Saravanakumar

“…A series of novel pyrrole fused benzoxazinones/quinoxalinones has been evaluated for antiproliferative activity against breast cancer cell line, MCF7 and…”
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Abstract PO5-06-07: Unravelling the role of PKC-eta in modulating the Hippo Pathway: a novel therapeutic strategy for triple-negative breast cancer metastasis by Belsamma, Liju Vijaya Steltar, Muraleedharan, Amitha, Jayaram, Divya Ram, Waidha, Kamran, Jagadeeshan, Sankar, Sinay, Rose, Eremenko, Ekaterina, Berner, Omer, Elkabets, Moshe, Livneh, Etta

“…Breast cancer (BC) is the leading cause of cancer-related deaths in women, with metastasis being the primary reason for BC mortality. Triple-Negative Breast…”
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Multi‐Component Approach for Synthesis of Quinolinyl‐1,4‐dihydropyridines, Evaluation of Cytotoxicity against MCF7 and Molecular Docking Studies by Suresh, Selvendran, Das, Souvik, Waidha, Kamaran, Maity, Ritwik, Basu, Biswarup, Rajendran, Saravanakumar

“…Tetrazolo[1,5‐a]quinoline‐4‐carbaldehyde, 3‐oxo‐3‐phenylpropanenitrile, and β‐enamine were reacted in one‐pot to obtain highly functionalized…”
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In Vitro and In Silico Anti‐plasmodial Evaluation of Newly Synthesized β‐Carboline Derivatives by Kumar, Vipin, Sachdeva, Cheryl, Waidha, Kamran, Sharma, Sunil, Ray, Devalina, Kumar Kaushik, Naveen, Saha, Biswajit

“…Series of novel thiourea and guanidine conjugated β‐carbolines along with other analogues of this class were designed and synthesized for in vitro antimalarial…”
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Hydroxy Piperlongumines: Synthesis, Antioxidant, Cytotoxic Effect on Human Cancer Cell Lines, Inhibitory Action and ADMET Studies by Subramani, Muthuraman, Ramamoorthy, Gayathri, Hemaiswarya, Shanmugam, Waidha, Kamran, Brindha, J., Balamurali, M. M., Doble, Mukesh, Rajendran, Saravanakumar

“…Piperlongumine, an anticancer natural product, was sequentially demethylated to obtain mono, di and trihydroxy piperlongumines. The hydroxy piperlongumines…”
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