Search Results - "Wai Lau, Chi"

Serum exosomes mediate delivery of arginase 1 as a novel mechanism for endothelial dysfunction in diabetes by Zhang, Huina, Liu, Jian, Qu, Dan, Wang, Li, Wong, Chi Ming, Lau, Chi-Wai, Huang, Yuhong, Wang, Yi Fan, Huang, Huihui, Xia, Yin, Xiang, Li, Cai, Zongwei, Liu, Pingsheng, Wei, Yongxiang, Yao, Xiaoqiang, Ma, Ronald Ching Wan, Huang, Yu

“…Exosomes, abundant in blood, deliver various molecules to recipient cells. Endothelial cells are directly exposed to circulating substances. However, how…”
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Angiotensin 1-7 Protects against Angiotensin II-Induced Endoplasmic Reticulum Stress and Endothelial Dysfunction via Mas Receptor by Murugan, Dharmani, Lau, Yeh Siang, Lau, Chi Wai, Lau, Wai Chi, Mustafa, Mohd Rais, Huang, Yu

“…Angiotensin 1-7 (Ang 1-7) counter-regulates the cardiovascular actions of angiotensin II (Ang II). The present study investigated the protective effect of Ang…”
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Indocyanine green fluorescence angiography to evaluate anastomotic perfusion in colorectal surgery by Tsang, Yi-po, Leung, Lik-Hang Alex, Lau, Chi-wai, Tang, Chung-ngai

“…Background The aim of this study was to evaluate the efficacy of indocyanine green (ICG) fluorescence angiography with respect to the anastomotic leakage rate…”
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Endothelial dysfunction after androgen deprivation therapy and the possible underlying mechanisms by Teoh, Jeremy Yuen‐Chun, Tian, Xiao‐Yu, Wong, Christine Yim‐Ping, Lau, Chi‐Wai, Cheng, Chak‐Kwong, Tang, Victor Wai‐Lun, Chan, Ronald Cheong‐Kin, Huang, Yu, Ng, Chi‐Fai

“…Introduction Androgen deprivation therapy (ADT) is a key treatment modality in the management of prostate cancer (PCa), especially for patients with metastatic…”
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Endothelial cell transient receptor potential channel C5 (TRPC5) is essential for endothelium-dependent contraction in mouse carotid arteries by Liang, Cai, Zhang, Yunting, Zhuo, Duan, Lo, Chun-Yin, Yu, Libo, Lau, Chi-Wai, Kwan, Yiu-Wa, Tse, Gary, Huang, Yu, Yao, Xiaoqiang

“…[Display omitted] Augmented endothelium-dependent contractions (EDC) contributes to endothelial dysfunction and vascular disease progression. An early signal…”
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Black tea protects against hypertension-associated endothelial dysfunction through alleviation of endoplasmic reticulum stress by San Cheang, Wai, Yuen Ngai, Ching, Yen Tam, Ye, Yu Tian, Xiao, Tak Wong, Wing, Zhang, Yang, Wai Lau, Chi, Chen, Zhen Yu, Bian, Zhao-Xiang, Huang, Yu, Ping Leung, Fung

“…Hypertensive patients have been found to be associated with elevated levels of homocysteine, known as hyperhomocysteinemia. Homocysteine (Hcy) can induce…”
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Activation of AMPK/miR-181b Axis Alleviates Endothelial Dysfunction and Vascular Inflammation in Diabetic Mice by Cheng, Chak-Kwong, Shang, Wenbin, Liu, Jian, Cheang, Wai-San, Wang, Yu, Xiang, Li, Lau, Chi-Wai, Luo, Jiang-Yun, Ng, Chi-Fai, Huang, Yu, Wang, Li

“…Hyperglycemia in diabetes mellitus impairs endothelial function and disrupts microRNA (miRNA) profiles in vasculature, increasing the risk of…”
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AMPK-Dependent YAP Inhibition Mediates the Protective Effect of Metformin against Obesity-Associated Endothelial Dysfunction and Inflammation by Kang, Lijing, Yi, Juanjuan, Lau, Chi-Wai, He, Lei, Chen, Qinghua, Xu, Suowen, Li, Jun, Xia, Yin, Zhang, Yuanting, Huang, Yu, Wang, Li

“…Hyperglycemia is a crucial risk factor for cardiovascular diseases. Chronic inflammation is a central characteristic of obesity, leading to many of its…”
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Focal TLR4 activation mediates disturbed flow-induced endothelial inflammation by Qu, Dan, Wang, Li, Huo, Mingyu, Song, Wencong, Lau, Chi-Wai, Xu, Jian, Xu, Aimin, Yao, Xiaoqiang, Chiu, Jeng-Jiann, Tian, Xiao Yu, Huang, Yu

“…Abstract Aims Disturbed blood flow at arterial branches and curvatures modulates endothelial function and predisposes the region to endothelial inflammation…”
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Berberine Reverses Nitroglycerin Tolerance through Suppressing Protein Kinase C Alpha Activity in Vascular Smooth Muscle Cells by Zhang, Huina, Dong, Jinghui, Lau, Chi-Wai, Huang, Yu

“…Purpose The aim of this study was to evaluate the effects of berberine on nitroglycerin (NTG) tolerance and explore the underlying mechanism involved. Methods…”
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The role of KLF2 in regulating hepatic lipogenesis and blood cholesterol homeostasis via the SCAP/SREBP pathway by Huang, Yuhong, Wang, Yi Fan, Ruan, Xiong Zhong, Lau, Chi Wai, Wang, Li, Huang, Yu

“…Liver steatosis is a common metabolic disorder resulting from imbalanced lipid metabolism, which involves various processes such as de novo lipogenesis, fatty…”
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Urocortin‐induced endothelium‐dependent relaxation of rat coronary artery: role of nitric oxide and K+ channels by Huang, Yu, Chan, Franky Leung, Lau, Chi‐Wai, Tsang, Suk‐Ying, He, Guo‐Wei, Chen, Zhen‐Yu, Yao, Xiaoqiang

“…The mechanisms underlying the vasodilator response to urocortin are incompletely understood. The present study was designed to examine the role of endothelial…”
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Dipeptidyl Peptidase 4 Inhibitor Sitagliptin Protects Endothelial Function in Hypertension Through a Glucagon–Like Peptide 1–Dependent Mechanism by Liu, Limei, Liu, Jian, Wong, Wing Tak, Tian, Xiao Yu, Lau, Chi Wai, Wang, Yi-Xiang, Xu, Gang, Pu, Yunfei, Zhu, Zhiming, Xu, Aimin, Lam, Karen S.L, Chen, Zhen Yu, Ng, Chi Fai, Yao, Xiaoqiang, Huang, Yu

“…Sitagliptin, a selective dipeptidyl peptidase 4 inhibitor, inhibits the inactivation and degradation of glucagon like peptide 1 (GLP-1), which is used for the…”
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Ginsenoside Rb3 attenuates oxidative stress and preserves endothelial function in renal arteries from hypertensive rats by Wang, Youhua, Dong, Jinghui, Liu, Ping, Lau, Chi Wai, Gao, Zhen, Zhou, Duan, Tang, Jingyi, Ng, Chi Fai, Huang, Yu

“…Background and Purpose Panax ginseng is commonly used to treat cardiovascular conditions in Oriental countries. This study investigated the mechanisms…”
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Uncoupling protein-2 mediates DPP-4 inhibitor-induced restoration of endothelial function in hypertension through reducing oxidative stress by Liu, Limei, Liu, Jian, Tian, Xiao Yu, Wong, Wing Tak, Lau, Chi Wai, Xu, Aimin, Xu, Gang, Ng, Chi Fai, Yao, Xiaoqiang, Gao, Yuansheng, Huang, Yu

“…Although uncoupling protein 2 (UCP2) negatively regulates intracellular reactive oxygen species (ROS) production and protects vascular function, its…”
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Integrated metabolomics analysis of the effect of PPARδ agonist GW501516 on catabolism of BCAAs and carboxylic acids in diabetic mice by Xiang, Li, Nie, Juan, Wang, Li, Wang, Yu, Shi, Jingchun, Wei, Juntong, Lau, Chi-Wai, Cai, Zongwei, Huang, Yu

“…PPARδ agonist GW501516 significantly altered the increased levels of metabolites associated with the impaired systemic insulin sensitivity. This study provides…”
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Vasorelaxant and antiproliferative effects of berberine by Ko, Wing-Hung, Yao, Xiao-Qiang, Lau, Chi-Wai, Law, Wai-Ip, Chen, Zhen-Yu, Kwok, Walter, Ho, Keung, Huang, Yu

“…The present study was intended to examine the relaxant effects of berberine in rat isolated mesenteric arteries. Berberine produced a rightward shift of the…”
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MSH2 c.1452–1455delAATG Is a Founder Mutation and an Important Cause of Hereditary Nonpolyposis Colorectal Cancer in the Southern Chinese Population by Chan, Tsun Leung, Wai Chan, Yee, Ho, Judy W.C., Chan, Celine, Chan, Annie S.Y., Chan, Emily, Lam, Polly W.Y., Wah Tse, Chun, Cheong Lee, Kam, Wai Lau, Chi, Gwi, Elaine, Yi Leung, Suet, Yuen, Siu Tsan

“…Hereditary nonpolyposis colorectal cancer (HNPCC) accounts for ∼2% of all colorectal cancer (CRC) cases and is the most common hereditary CRC syndrome. We have…”
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Adiponectin Is Required for PPARγ-Mediated Improvement of Endothelial Function in Diabetic Mice by Wong, Wing Tak, Tian, Xiao Yu, Xu, Aimin, Yu, Jun, Lau, Chi Wai, Hoo, Ruby L.C., Wang, Yu, Lee, Vivian W.Y., Lam, Karen S.L., Vanhoutte, Paul M., Huang, Yu

“…Rosiglitazone is a PPARγ agonist commonly used to treat diabetes. In addition to improving insulin sensitivity, rosiglitazone restores normal vascular function…”
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Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via adenosine monophosphate-activated protein kinase and endothelial nitric oxide synthase by Wang, Yiqun, Huang, Yu, Lam, Karen S.L., Li, Yiming, Wong, Wing Tak, Ye, Hongying, Lau, Chi-Wai, Vanhoutte, Paul M., Xu, Aimin

“…Aims Endothelial dysfunction is a key event that links obesity, diabetes, hypertension, and cardiovascular diseases. The aim of the present study was to…”
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