Search Results - "Wai, Tint"
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Development of a Live Attenuated Bivalent Oral Vaccine Against Shigella sonnei Shigellosis and Typhoid Fever
Published in The Journal of infectious diseases (15-01-2017)“…Shigella sonnei and Salmonella Typhi cause significant morbidity and mortality. We exploited the safety record of the oral, attenuated S. Typhi vaccine (Ty21a)…”
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Comparing invasive effects of five foodborne bacterial pathogens in human embryonic intestine 407 cells and human ileocecum HCT-8 cells
Published in Asian Pacific journal of tropical biomedicine (01-10-2017)“…Objective: To refine the infectious doses of enteric bacterial pathogens in animal assays and vaccine clinical trials by studying the invasion kinetics of five…”
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The prevalence of lymphatic filariasis infection and disease following six rounds of mass drug administration in Mandalay Region, Myanmar
Published in PLoS neglected tropical diseases (01-11-2018)“…Lymphatic filariasis is widely endemic in Myanmar. Despite the establishment of an elimination program in 2000, knowledge of the remaining burden of disease…”
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Risk factors for lymphatic filariasis and mass drug administration non-participation in Mandalay Region, Myanmar
Published in Parasites & vectors (22-01-2021)“…Myanmar commenced a lymphatic filariasis (LF) elimination programme in 2000. Whilst the country has made considerable progress since then, a number of…”
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Preventive chemotherapy reverses covert, lymphatic‐associated tissue change in young people with lymphatic filariasis in Myanmar
Published in Tropical medicine & international health (01-04-2019)“…Objectives This longitudinal comparative study investigated the effect of preventive chemotherapy (PC) on covert tissue changes associated with lymphatic…”
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Stable expression of Shigella sonnei form I O-polysaccharide genes recombineered into the chromosome of live Salmonella oral vaccine vector Ty21a
Published in International journal of medical microbiology (01-04-2013)“…Abstract Live, attenuated Salmonella enterica serovar Typhi strain Ty21a, a licensed oral typhoid fever vaccine, has also been employed for use as a vector to…”
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Protection against inhalation anthrax by immunization with Salmonella enterica serovar Typhi Ty21a stably producing protective antigen of Bacillus anthracis
Published in npj vaccines (15-06-2017)“…The national blueprint for biodefense concluded that the United States is underprepared for biological threats. The licensed anthrax vaccine absorbed vaccine,…”
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Lymphatic Filariasis Increases Tissue Compressibility and Extracellular Fluid in Lower Limbs of Asymptomatic Young People in Central Myanmar
Published in Tropical medicine and infectious disease (27-09-2017)“…When normal lymphatic function is hampered, imperceptible subcutaneous edema can develop and progress to overt lymphedema. Low-cost reliable devices for…”
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Core-linked LPS expression of Shigella dysenteriae serotype 1 O-antigen in live Salmonella Typhi vaccine vector Ty21a: Preclinical evidence of immunogenicity and protection
Published in Vaccine (14-08-2007)“…Abstract Shigella dysenteriae serotype 1 ( S. dysenteriae 1) causes severe shigellosis that is typically associated with high mortality. Antibodies against…”
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In vitro production of infectious Plasmodium falciparum sporozoites
Published in Nature (London) (15-12-2022)“…An effective vaccine is needed for the prevention and elimination of malaria. The only immunogens that have been shown to have a protective efficacy of more…”
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Lymphatic filariasis increases tissue compressibility and extracellular fluid in lower limbs of asymptomatic young people in central Myanmar
Published in Tropical medicine and infectious disease (01-12-2017)“…When normal lymphatic function is hampered, imperceptible subcutaneous edema can develop and progress to overt lymphedema. Low-cost reliable devices for…”
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Genome Sequence of Salmonella enterica Serovar Typhi Oral Vaccine Strain Ty21a
Published in Genome announcements (Washington, DC) (22-08-2013)“…Attenuated Salmonella enterica serovar Typhi strain Ty21a is an important vaccine for controlling typhoid fever and serves as an oral vector for delivering…”
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Synthesis and Discovery of Estra-1,3,5(10),6,8-pentaene-2,16α-diol
Published in Organic letters (05-10-2018)“…A metallacycle-centered approach to the assembly of partially aromatic synthetic steroids was investigated as a means to prepare a boutique collection of…”
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Core-linked LPS expression ofShigella dysenteriaeserotype 1 O-antigen in liveSalmonellaTyphi vaccine vector Ty21a: Preclinical evidence of immunogenicity and protection
Published in Vaccine (14-08-2007)“…Shigella dysenteriaeserotype 1 (S. dysenteriae1) causes severe shigellosis that is typically associated with high mortality. Antibodies…”
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Efforts Towards the Asymmetric de novo Synthesis of Lanostanes and Euphanes
Published 01-01-2022“…Tetracyclic triterpenoids are ubiquitous in nature and biology, with members displaying a wide range of medically relevant properties and occupying rather…”
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Dissertation