Search Results - "Wahle, Klaus W."

Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines by Brown, Iain, Cascio, Maria G., Wahle, Klaus W.J., Smoum, Reem, Mechoulam, Raphael, Ross, Ruth A., Pertwee, Roger G., Heys, Steven D.

“…The omega-3 fatty acid ethanolamides, docosahexaenoyl ethanolamide (DHEA) and eicosapentaenoyl ethanolamide (EPEA), displayed greater anti-proliferative…”
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Age-related increases in circulating inflammatory markers in men are independent of BMI, blood pressure and blood lipid concentrations by Miles, Elizabeth A, Rees, Dinka, Banerjee, Tapati, Cazzola, Roberta, Lewis, Sian, Wood, Richard, Oates, Rachael, Tallant, Anna, Cestaro, Benvenuto, Yaqoob, Parveen, Wahle, Klaus W.J, Calder, Philip C

“…Abstract Objective To examine whether age-related increase in concentrations of circulating inflammatory mediators is due to concurrent increases in…”
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Conjugated linoleic acids (CLAs) decrease prostate cancer cell proliferation: different molecular mechanisms for cis-9, trans-11 and trans-10, cis-12 isomers by Ochoa, Julio J., Farquharson, Andrew J., Grant, Ian, Moffat, L. E., Heys, Steven D., Wahle, Klaus W. J.

“…The aims of this study were to examine the anti-proliferative effects of different concentrations of a commercial preparation of conjugated linoleic acids…”
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Plant phenolics in the prevention and treatment of cancer by Wahle, Klaus W J, Brown, Iain, Rotondo, Dino, Heys, Steven D

“…Epidemiological studies indicate that populations consuming high levels of plant derived foods have low incidence rates of various cancers. Recent findings…”
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Age- and dose-dependent effects of an eicosapentaenoic acid-rich oil on cardiovascular risk factors in healthy male subjects by Cazzola, Roberta, Russo-Volpe, Samantha, Miles, Elizabeth A, Rees, Dinka, Banerjee, Tapati, Roynette, Catherine E, Wells, Solenne J, Goua, Marie, Wahle, Klaus W.J, Calder, Philip C, Cestaro, Benvenuto

“…Abstract Supplementation with fish oils, rich in n − 3 polyunsaturated fatty acids, modifies cardiovascular risk factors. However, dose–response relationships…”
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Cognitive aging, childhood intelligence, and the use of food supplements: possible involvement of n-3 fatty acids by Whalley, L.J, Fox, H.C, Wahle, K.W, Starr, J.M, Deary, I.J

“…Background: Food supplement use is widely promoted, but little is known about the cognitive effects of food supplements. Objective: We examined the effects of…”
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Enhancing Cytotoxic Therapies for Breast and Prostate Cancers With Polyunsaturated Fatty Acids by Shaikh, Irshad, A.A, Brown, Iain, Wahle, Klaus W.J, Heys, Steven D

“…The role of omega-3 and omega-6 fatty acids has been extensively studied in most of the human malignancies including breast, colon, prostate, pancreas, and…”
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Dose-related effects of eicosapentaenoic acid on innate immune function in healthy humans: a comparison of young and older men by Rees, Dinka, Miles, Elizabeth A, Banerjee, Tapati, Wells, Solenne J, Roynette, Catherine E, Wahle, Klaus WJ, Calder, Philip C

“…BACKGROUND: Increasing intakes of long-chain n-3 polyunsaturated fatty acids (PUFAs) can decrease markers of immunity. However, dose- and age-related responses…”
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Cytoprotective effects of phenolic antioxidants and essential fatty acids in human blood monocyte and neuroblastoma cell lines: Surrogates for neurological damage in vivo by Young, Julie, Wahle, Klaus W.J, Boyle, Susanne P

“…Abstract Background Oxidative stress is implicated in the development of a range of neurological diseases. There is increasing interest in the neuroprotective…”
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Olive oil phenolics: effects on DNA oxidation and redox enzyme mRNA in prostate cells by Quiles, José L., Farquharson, Andrew J., Simpson, David K., Grant, Ian, Wahle, Klaus W. J.

“…Hydroxytyrosol, tyrosol and caffeic acid effects on hydrogen peroxide-induced DNA damage, hydroperoxide generation and redox enzyme gene expression were…”
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Anticancer effects of n-3 EPA and DHA and their endocannabinoid derivatives on breast cancer cell growth and invasion by Brown, Iain, Lee, Jisun, Sneddon, Alan A., Cascio, Maria G., Pertwee, Roger G., Wahle, Klaus W.J., Rotondo, Dino, Heys, Steven D.

“…•EPEA and DHEA have greater anti-cancer effects than EPA and DHA in breast cancer cells.•EPEA and DHEA showed no effects in normal breast cells.•CB1/2…”
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Potentiation of the anti-tumour effect of docetaxel by conjugated linoleic acids (CLAs) in breast cancer cells in vitro by Fite, Alemu, Goua, Marie, Wahle, Klaus W.J, Schofield, Andrew C, Hutcheon, Andrew W, Heys, Steven D

“…Abstract Response rates of tumours to docetaxel (DOCT) are 45–60% in advanced breast cancer but problems associated with side effects, drug resistance and high…”
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Olive oil and modulation of cell signaling in disease prevention by Wahle, K.W.J, Caruso, D, Ochoa, J.J, Quiles, J.L

“…Epidemiological studies show that populations consuming a predominantly plant‐based Mediterranean‐style diet exhibit lower incidences of chronic diseases than…”
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Cannabinoids and omega-3/6 endocannabinoids as cell death and anticancer modulators by Brown, Iain, Cascio, Maria G., Rotondo, Dino, Pertwee, Roger G., Heys, Steven D., Wahle, Klaus W.J.

“…Cannabinoids-endocannaboids are possible preventatives of common diseases including cancers. Cannabinoid receptors (CB1/2, TRPV1) are central components of the…”
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Circulating levels of angiogenesis-related growth factors in breast cancer: A study to profile proteins responsible for tubule formation by Barron, Gemma A, Goua, Marie, Wahle, Klaus W.J, Bermano, Giovanna

“…The present study exploited a versatile in vitro endothelial cell/fibroblast co-culture cell system to investigate the association between angiogenesis and…”
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n-3 Fatty acid erythrocyte membrane content, APOE ε4, and cognitive variation: an observational follow-up study in late adulthood by Whalley, Lawrence J, Deary, Ian J, Starr, John M, Wahle, Klaus W, Rance, Kellie A, Bourne, Victoria J, Fox, Helen C

“…BACKGROUND: Evidence for an inverse relation between dietary intake of n-3 polyunsaturated fatty acids (PUFAs) and age-related cognitive decline is…”
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Dietary supplementation with conjugated linoleic acid plus n-3 polyunsaturated fatty acid increases food intake and brown adipose tissue in rats by Sneddon, Alan A, Rayner, D Vernon, Mitchell, Sharon E, Bashir, Shabina, Ha, Jung-Heun, Wahle, Klaus W, Morris, Amanda C, Williams, Lynda M

“…The effect of supplementation with 1% conjugated linoleic acid and 1% n-3 long chain polyunsaturated fatty acids (CLA/n-3) was assessed in rats. Food intake…”
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Atherosclerosis: cell biology and lipoproteins by Wahle, Klaus W J, Heys, Steven D

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Conjugated linoleic acid inhibits proliferation and modulates protein kinase C isoforms in human prostate cancer cells by Song, H.J, Sneddon, A.A, Barker, P.A, Bestwick, C, Choe, S.N, McClinton, S, Grant, I, Rotondo, D, Heys, S.D, Wahle, K.W.J

“…Prostate cancer is the second most common cancer in men. The disease etiology is poorly understood, but diet and lifestyle are contributory factors. Conjugated…”
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Effect of a Conjugated Linoleic Acid and omega-3 Fatty Acid Mixture on Body Composition and Adiponectin by Sneddon, Alan A, Tsofliou, Fotini, Fyfe, Claire L, Matheson, Ian, Jackson, Diane M, Horgan, Graham, Winzell, Maria S, Wahle, Klaus W.J, Ahren, Bo, Williams, Lynda M

“…This study aimed to determine the effect of supplementation with conjugated linoleic acids (CLAs) plus n-3 long-chain polyunsaturated fatty acids (n-3…”
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