Search Results - "Wahie, Shyamal"

Clinical and genetic differences between pustular psoriasis subtypes by Twelves, Sophie, Mostafa, Alshimaa, Dand, Nick, Burri, Elias, Farkas, Katalin, Wilson, Rosemary, Cooper, Hywel L., Irvine, Alan D., Oon, Hazel H., Kingo, Külli, Köks, Sulev, Mrowietz, Ulrich, Puig, Luis, Reynolds, Nick, Tan, Eugene Sern-Ting, Tanew, Adrian, Torz, Kaspar, Trattner, Hannes, Valentine, Mark, Wahie, Shyamal, Warren, Richard B., Wright, Andrew, Bata-Csörgő, Zsuzsa, Szell, Marta, Griffiths, Christopher E.M., Burden, A. David, Choon, Siew-Eng, Smith, Catherine H., Barker, Jonathan N., Navarini, Alexander A., Capon, Francesca

“…The term pustular psoriasis indicates a group of severe skin disorders characterized by eruptions of neutrophil-filled pustules. The disease, which often…”
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Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne by Petridis, Christos, Navarini, Alexander A., Dand, Nick, Saklatvala, Jake, Baudry, David, Duckworth, Michael, Allen, Michael H., Curtis, Charles J., Lee, Sang Hyuck, Burden, A. David, Layton, Alison, Bataille, Veronique, Pink, Andrew E., Carlavan, Isabelle, Voegel, Johannes J., Spector, Timothy D., Trembath, Richard C., McGrath, John A., Smith, Catherine H., Barker, Jonathan N., Simpson, Michael A.

“…Acne vulgaris is a highly heritable common, chronic inflammatory disease of the skin for which five genetic risk loci have so far been identified. Here, we…”
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Home-based narrowband UVB, topical corticosteroid or combination for children and adults with vitiligo: HI-Light Vitiligo three-arm RCT by Batchelor, Jonathan M, Thomas, Kim S, Akram, Perways, Azad, Jaskiran, Bewley, Anthony, Chalmers, Joanne R, Cheung, Seau Tak, Duley, Lelia, Eleftheriadou, Viktoria, Ellis, Robert, Ferguson, Adam, Goulding, Jonathan Mr, Haines, Rachel H, Hamad, Hamdi, Ingram, John R, Laguda, Bisola, Leighton, Paul, Levell, Nick, Makrygeorgou, Areti, Meakin, Garry D, Millington, Adam, Ogboli, Malobi, Rajasekaran, Amirtha, Ravenscroft, Jane C, Rogers, Andrew, Sach, Tracey H, Santer, Miriam, Stainforth, Julia, Tan, Wei, Wahie, Shyamal, White, Jennifer, Whitton, Maxine E, Williams, Hywel C, Wright, Andrew, Montgomery, Alan A

“…Systematic reviews suggest that narrowband ultraviolet B light combined with treatments such as topical corticosteroids may be more effective than monotherapy…”
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Using Real‐World Data to Guide Ustekinumab Dosing Strategies for Psoriasis: A Prospective Pharmacokinetic‐Pharmacodynamic Study by Pan, Shan, Tsakok, Teresa, Dand, Nick, Lonsdale, Dagan O., Loeff, Floris C., Bloem, Karien, Vries, Annick, Baudry, David, Duckworth, Michael, Mahil, Satveer, Pushpa‐Rajah, Angela, Russell, Alice, Alsharqi, Ali, Becher, Gabrielle, Murphy, Ruth, Wahie, Shyamal, Wright, Andrew, Griffiths, Christopher E.M., Reynolds, Nick J., Barker, Jonathan, Warren, Richard B., David Burden, A., Rispens, Theo, Standing, Joseph F., Smith, Catherine H., Benham, Marilyn, Evans, Ian, Hussain, Sagair, Kirby, Brian, Lawson, Linda, Mason, Kayleigh, McElhone, Kathleen, Ormerod, Anthony, Owen, Caroline, Barnes, Michael R., Di Meglio, Paola, Emsley, Richard, Evans, Andrea, Payne, Katherine

“…Variation in response to biologic therapy for inflammatory diseases, such as psoriasis, is partly driven by variation in drug exposure. Real‐world psoriasis…”
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PD05 Investigating the course of atopic eczema up to 1 year following completion of narrowband ultraviolet B phototherapy by Jain, Dimple, Bajaj, Sonali, Desai, Prachi, Wahie, Shyamal

“…Abstract Narrowband UVB (NBUVB) is a recommended second-line treatment for moderate-to-severe atopic eczema unresponsive to adequate topical therapy, and is…”
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HLA-C06:02 genotype is a predictive biomarker of biologic treatment response in psoriasis by Dand, Nick, Duckworth, Michael, Baudry, David, Russell, Alice, Curtis, Charles J., Lee, Sang Hyuck, Evans, Ian, Mason, Kayleigh J., Alsharqi, Ali, Becher, Gabrielle, Burden, A. David, Goodwin, Richard G., McKenna, Kevin, Murphy, Ruth, Perera, Gayathri K., Rotarescu, Radu, Wahie, Shyamal, Wright, Andrew, Reynolds, Nick J., Warren, Richard B., Griffiths, Christopher E.M., Smith, Catherine H., Simpson, Michael A., Barker, Jonathan N., Benham, Marilyn, Hussain, Sagair, Kirby, Brian, Lawson, Linda, McElhone, Kathleen, Ormerod, Anthony, Owen, Caroline, Barnes, Michael R., Di Meglio, Paola, Emsley, Richard, Evans, Andrea, Payne, Katherine, Stocken, Deborah

“…Biologic therapies can be highly effective for the treatment of severe psoriasis, but response for individual patients can vary according to drug. Predictive…”
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Loss-of-Function Myeloperoxidase Mutations Are Associated with Increased Neutrophil Counts and Pustular Skin Disease by Vergnano, Marta, Mockenhaupt, Maja, Benzian-Olsson, Natashia, Paulmann, Maren, Grys, Katarzyna, Mahil, Satveer K., Chaloner, Charlotte, Barbosa, Ines A., August, Suzannah, Burden, A. David, Choon, Siew-Eng, Cooper, Hywel, Navarini, Alex A., Reynolds, Nick J., Wahie, Shyamal, Warren, Richard B., Wright, Andrew, Abraham, Thamir, Ali, Mahmud, August, Suzannah, Baudry, David, Bewley, Anthony, Cooper, Hywel, Griffiths, Christopher E.M., Ingram, John, Kelly, Susan, Korshid, Mohsen, Ladoyanni, Effie, McKenna, John, Meynell, Freya, Parslew, Richard, Patel, Prakash, Pushparajah, Angela, Reynolds, Nick, Smith, Catherine, Wahie, Shyamal, Warren, Richard, Wright, Andrew, Huffmeier, Ulrike, Baum, Patrick, Visvanathan, Sudha, Barker, Jonathan N., Smith, Catherine H., Capon, Francesca

“…The identification of disease alleles underlying human autoinflammatory diseases can provide important insights into the mechanisms that maintain neutrophil…”
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A genome-wide meta-analysis of palmoplantar pustulosis implicates TH2 responses and cigarette smoking in disease pathogenesis by Hernandez-Cordero, Ariana, Thomas, Laurent, Smail, Alice, Lim, Zhao Qin, Saklatvala, Jake R., Chung, Raymond, Curtis, Charles J., Baum, Patrick, Visvanathan, Sudha, Burden, A. David, Cooper, Hywel L., Dunnill, Giles, Griffiths, Christopher E.M., Levell, Nick J., Parslew, Richard, Reynolds, Nick J., Wahie, Shyamal, Warren, Richard B., Wright, Andrew, Abraham, Thamir, Ali, Muhmad, August, Suzannah, Baudry, David, Becher, Gabrielle, Bewley, Anthony, Brown, Victoria, Cornelius, Victoria, Ghaffar, Sharizan, Ingram, John, Kavakleiva, Svetlana, Kelly, Susan, Khorshid, Mohsen, Lachmann, Helen, Ladoyanni, Effie, McAteer, Helen, McKenna, John, Meynell, Freya, Patel, Prakash, Pink, Andrew, Powell, Kingsley, Pushparajah, Angela, Sinclair, Catriona, Wachsmuth, Rachel, Simpson, Michael, Hveem, Kristian, Barker, Jonathan N., Dand, Nick, Løset, Mari, Smith, Catherine H., Capon, Francesca

“…Palmoplantar pustulosis (PPP) is an inflammatory skin disorder that mostly affects smokers and manifests with painful pustular eruptions on the palms and…”
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Differences in Clinical Features and Comorbid Burden between HLA-C∗06:02 Carrier Groups in >9,000 People with Psoriasis by Douroudis, Konstantinos, Ramessur, Ravi, Barbosa, Ines A., Baudry, David, Duckworth, Michael, Angit, Caroline, Capon, Francesca, Curtis, Charles J., Di Meglio, Paola, Goulding, Jonathan M.R., Griffiths, Christopher E.M., Lee, Sang Hyuck, Mahil, Satveer K., Parslew, Richard, Reynolds, Nick J., Shipman, Alexa R., Warren, Richard B., Yiu, Zenas Z.N., Simpson, Michael A., Dand, Nick, Smith, Catherine H., Evans, Ian, Murphy, Ruth, McPherson, Tess, Kleyn, Elise, Laws, Philip, Rashid, Amir, Alabas, Oras, Morrison, Simon, Ahmed, Shehnaz, Pearson, Eleanor, Richards, Josh, Mackenzie, Teena, Kirby, Brian, Burden, David, Lawson, Linda, McElhone, Kathleen, Ormerod, Anthony, Owen, Caroline, Ali, Mahmud, Anstey, Alex, Antony, Fiona, Archer, Charles, August, Suzanna, Balasubramaniam, Periasamy, Baxter, Kay, Bonsall, Alexandra, Brown, Victoria, Burova, Katya, Butt, Aamir, Cliff, Sandeep, Costache, Mihaela, Darne, Sharmela, Davies, Emily, DeGiovanni, Claudia, Desai, Trupti, DeSilva, Bernadette, Diba, Victoria, Domanne, Eva, Fahy, Caoimhe, Ferguson, Leila, Gkini, Maria-Angeliki, Godwin, Alison, Hammonds, Fiona, Johnson, Sarah, Joseph, Teresa, Kalavala, Manju, Khorshid, Mohsen, Labinoti, Liberta, Lawson, Nicole, Layton, Alison, Lees, Tara, Levell, Nick, Lyon, Calum, McBride, Sandy, McCormack, Sally, McKenna, Kevin, Mellor, Serap, Popli, Urvi, Perera, Gay, Ponnambath, Nabil, Ramsay, Helen, Ranasinghe, Aruni, Reeken, Saskia, Rose, Rebecca, Rotarescu, Rada, Salvary, Ingrid, Sands, Kathy, Sinha, Tapati, Stefanescu, Simina, Sundararaj, Kavitha, Taylor, Michelle, Topliffe, Joanne, Verdolini, Roberto, Wachsmuth, Rachel, Wade, Martin, Walsh, Sarah, Walton, Shernaz, Wilcox, Louise, Wright, Andrew

“…The identification of robust endotypes—disease subgroups of clinical relevance—is fundamental to stratified medicine. We hypothesized that HLA-C∗06:02 status,…”
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Association of Clinical and Demographic Factors With the Severity of Palmoplantar Pustulosis by Benzian-Olsson, Natashia, Dand, Nick, Chaloner, Charlotte, Bata-Csorgo, Zsuzsa, Borroni, Riccardo, Burden, A David, Cooper, Hywel L, Cornelius, Victoria, Cro, Suzie, Dasandi, Tejus, Griffiths, Christopher E M, Kingo, Külli, Koks, Sulev, Lachmann, Helen, McAteer, Helen, Meynell, Freya, Mrowietz, Ulrich, Parslew, Richard, Patel, Prakash, Pink, Andrew E, Reynolds, Nick J, Tanew, Adrian, Torz, Kaspar, Trattner, Hannes, Wahie, Shyamal, Warren, Richard B, Wright, Andrew, Barker, Jonathan N, Navarini, Alexander A, Smith, Catherine H, Capon, Francesca

“…Although palmoplantar pustulosis (PPP) can significantly impact quality of life, the factors underlying disease severity have not been studied. To examine the…”
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Loss-of-function myeloperoxidase mutations are associated with increased neutrophil counts and pustular skin disease by Vergnano, Marta, Mockenhaupt, Maja, Benzian-Olsson, Natashia, Paulmann, Maren, Grys, Katarzyna, Mahil, Satveer K., Chaloner, Charlotte, Barbosa, Ines A., August, Suzannah, Burden, A. David, Choon, Siew-Eng, Cooper, Hywel, Navarini, Alex A., Reynolds, Nick J., Wahie, Shyamal, Warren, Richard B., Wright, Andrew, Abraham, Thamir, Ali, Mahmud, Baudry, David, Bewley, Anthony, Griffiths, Christopher E.M., Ingram, John, Kelly, Susan, Korshid, Mohsen, Ladoyanni, Effie, McKenna, John, Meynell, Freya, Parslew, Richard, Patel, Prakash, Pushparajah, Angela, Reynolds, Nick, Smith, Catherine, Warren, Richard, Huffmeier, Ulrike, Baum, Patrick, Visvanathan, Sudha, Barker, Jonathan N., Smith, Catherine H., Capon, Francesca

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Damaging Alleles Affecting Multiple CARD14 Domains Are Associated with Palmoplantar Pustulosis by Niaouris, Athanasios, Hernández-Cordero, Ariana, Haddad, Salma, Hassi, Niina Karoliina, Benzian-Olsson, Natashia, Bugarin Diz, Carmen, Burden, A. David, Cooper, Hywel L., Griffiths, Christopher E.M., Parslew, Richard, Pink, Andrew E., Reynolds, Nick J., Wahie, Shyamal, Warren, Richard B., Wright, Andrew, Simpson, Michael, Baum, Patrick, Visvanathan, Sudha, Barker, Jonathan N., Smith, Catherine H., Capon, Francesca, Abraham, Thamir, Ali, Muhmad, August, Suzannah, Baudry, David, Becher, Gabrielle, Bewley, Anthony, Cornelius, Victoria, Dunnill, Giles, Ferguson, Adam, Ghaffar, Sharizan, Ingram, John, Kavakleiva, Svetlana, Kelly, Susan, Khorshid, Mohsen, Lachmann, Helen, Ladoyanni, Effie, McAteer, Helen, McKenna, John, Meynell, Freya, Levell, Nick, Patel, Prakash, Pushparajah, Angela, Sinclair, Catriona, Wachsmuth, Rachel, Wilson, Rosemary

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Clinical and Pharmacogenetic Influences on Response to Hydroxychloroquine in Discoid Lupus Erythematosus: A Retrospective Cohort Study by Wahie, Shyamal, Daly, Ann K., Cordell, Heather J., Goodfield, Mark J., Jones, Stephen K., Lovell, Christopher R., Carmichael, Andrew J., Carr, Mary M., Drummond, Angela, Natarajan, Sivakumar, Smith, Catherine H., Reynolds, Nick J., Meggitt, Simon J.

“…The recommended systemic therapy of choice for discoid lupus erythematosus (DLE) is the 4-aminoquinolone antimalarial hydroxychloroquine. There is limited…”
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Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris by Navarini, Alexander A., Simpson, Michael A., Weale, Michael, Knight, Jo, Carlavan, Isabelle, Reiniche, Pascale, Burden, David A., Layton, Alison, Bataille, Veronique, Allen, Michael, Pleass, Robert, Pink, Andrew, Creamer, Daniel, English, John, Munn, Stephanie, Walton, Shernaz, Willis, Carolyn, Déret, Sophie, Voegel, Johannes J., Spector, Tim, Smith, Catherine H., Trembath, Richard C., Barker, Jonathan N.

“…Acne vulgaris (acne) is a common inflammatory disorder of the cutaneous pilo-sebaceous unit. Here we perform a genome-wide association analysis in the United…”
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A genome-wide meta-analysis of palmoplantar pustulosis implicates T H 2 responses and cigarette smoking in disease pathogenesis by Hernandez-Cordero, Ariana, Thomas, Laurent, Smail, Alice, Lim, Zhao Qin, Saklatvala, Jake R, Chung, Raymond, Curtis, Charles J, Baum, Patrick, Visvanathan, Sudha, Burden, A David, Cooper, Hywel L, Dunnill, Giles, Griffiths, Christopher E M, Levell, Nick J, Parslew, Richard, Reynolds, Nick J, Wahie, Shyamal, Warren, Richard B, Wright, Andrew, Simpson, Michael, Hveem, Kristian, Barker, Jonathan N, Dand, Nick, Løset, Mari, Smith, Catherine H, Capon, Francesca

“…Palmoplantar pustulosis (PPP) is an inflammatory skin disorder that mostly affects smokers and manifests with painful pustular eruptions on the palms and…”
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An unusual erysipelas-like presentation by Siah, Tee Wei, Lavender, Thomas, Charlton, Fraser, Wahie, Shyamal, Schwab, Ulrich

“…A 61-year-old man presented with erysipelas-like cutaneous leishmaniasis…”
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Positive photocontact responses are not elicited to sunscreen ingredients exposed to UVA prior to application onto the skin by Wahie, Shyamal, Lloyd, James J, Farr, Peter M

“…Photocontact allergic reactions to sunscreen chemicals are investigated by photopatch testing. It has generally been assumed that for photocontact allergy to…”
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An ancient malady by Wahie, Shyamal, Ong, Edmund, Charlton, Fraser G, Reynolds, Nick J

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Wound complications following diagnostic skin biopsies in dermatology inpatients by Wahie, Shyamal, Lawrence, Clifford M

“…To prospectively determine the wound complication rate for dermatology inpatients undergoing diagnostic skin biopsies during their admission and to determine…”
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Papulonodular eruption, proteinuria, and peripheral arthritis. Papulonodular dermal mucinosis (PDM) in systemic lupus erythematosus by Rajan, Neil, Wahie, Shyamal, Seukeran, Daron

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