Search Results - "Wahajuddin, M"
-
1
Mechanism for antiParkinsonian effect of resveratrol: Involvement of transporters, synaptic proteins, dendrite arborization, biochemical alterations, ER stress and apoptosis
Published in Food and chemical toxicology (01-09-2021)“…The present study was undertaken to evaluate the mechanism for antiParkinsonian effect of resveratrol employing 6-hydroxydopamine (6-OHDA) induced experimental…”
Get full text
Journal Article -
2
4-Phenylbutyrate Mitigates the Motor Impairment and Dopaminergic Neuronal Death During Parkinson’s Disease Pathology via Targeting VDAC1 Mediated Mitochondrial Function and Astrocytes Activation
Published in Neurochemical research (01-11-2022)“…Parkinson’s disease (PD) is a progressive motor neurodegenerative disorder significantly associated with protein aggregation related neurodegenerative…”
Get full text
Journal Article -
3
Fatty acid synthase modulates proliferation, metabolic functions and angiogenesis in hypoxic pulmonary artery endothelial cells
Published in European journal of pharmacology (15-11-2017)“…Endothelial dysfunction plays an important role in structural remodeling occurring in the pulmonary vasculature during pulmonary hypertension (PH). Endothelial…”
Get full text
Journal Article -
4
-
5
Dopamine receptor activation mitigates mitochondrial dysfunction and oxidative stress to enhance dopaminergic neurogenesis in 6-OHDA lesioned rats: A role of Wnt signalling
Published in Neurochemistry international (01-10-2019)“…Nigral dopaminergic (DAergic) cell degeneration and depletion of dopamine neurotransmitter in the midbrain are cardinal features of Parkinson's disease (PD)…”
Get full text
Journal Article -
6
Antileishmanial Activity of Pyrazolopyridine Derivatives and Their Potential as an Adjunct Therapy with Miltefosine
Published in Journal of medicinal chemistry (09-02-2017)“…A series of pyrazolo(dihydro)pyridines was synthesized and evaluated for antileishmanial efficacy against experimental visceral leishmaniasis (VL). Among all…”
Get full text
Journal Article -
7
New therapeutic activity of metabolic enhancer piracetam in treatment of neurodegenerative disease: Participation of caspase independent death factors, oxidative stress, inflammatory responses and apoptosis
Published in Biochimica et biophysica acta. Molecular basis of disease (01-06-2018)“…Piracetam, a nootropic drug that has been clinically used for decades but remains enigmatic due to no distinct understanding of its mechanism of action. The…”
Get full text
Journal Article -
8
Naturally Occurring Carbazole Alkaloids from Murraya koenigii as Potential Antidiabetic Agents
Published in Journal of natural products (Washington, D.C.) (27-05-2016)“…This study identified koenidine (4) as a metabolically stable antidiabetic compound, when evaluated in a rodent type 2 model (leptin receptor-deficient db/db…”
Get full text
Journal Article -
9
β-Amino acid derivatives as mitochondrial complex III inhibitors of L. donovani: A promising chemotype targeting visceral leishmaniasis
Published in European journal of medicinal chemistry (15-11-2019)“…β-amino acids and their analogues are gathering increased attention not only because of their antibacterial and antifungal activity, but also for their use in…”
Get full text
Journal Article -
10
Phytochemical analysis of isoflavonoids using liquid chromatography coupled with tandem mass spectrometry
Published in Phytochemistry reviews (01-06-2015)“…Isoflavonoids are the biologically active secondary metabolites of plants that are being used for several health promoting and restoring effects mediated…”
Get full text
Journal Article -
11
Pharmacokinetic endeavors for antimalarial therapeutics
Published in International journal of infectious diseases (01-04-2016)Get full text
Journal Article