Search Results - "Wagstaff, Reece"
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Low levels of SIV-specific CD8+ T cells in germinal centers characterizes acute SIV infection
Published in PLoS pathogens (01-03-2019)“…CD8+ T cells play an important role in controlling of HIV and SIV infections. However, these cells are largely excluded from B cell follicles where HIV and SIV…”
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2
Simian Immunodeficiency Virus-Producing Cells in Follicles Are Partially Suppressed by CD8+ Cells In Vivo
Published in Journal of virology (15-12-2016)“…Human immunodeficiency virus (HIV)- and simian immunodeficiency virus (SIV)-specific CD8 T cells are typically largely excluded from lymphoid B cell follicles,…”
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3
Compartmentalization of simian immunodeficiency virus replication within secondary lymphoid tissues of rhesus macaques is linked to disease stage and inversely related to localization of virus-specific CTL
Published in The Journal of immunology (1950) (01-12-2014)“…We previously demonstrated that HIV replication is concentrated in lymph node B cell follicles during chronic infection and that HIV-specific CTL fail to…”
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4
Location and dynamics of the immunodominant CD8 T cell response to SIVΔnef immunization and SIVmac251 vaginal challenge
Published in PloS one (09-12-2013)“…Live-attenuated SIV vaccines (LAVs) have been the most effective to date in preventing or partially controlling infection by wild-type SIV in non-human primate…”
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5
SIV-specific CD8 T cells with perforin granules located exclusively within cell membranes correlate with the maturation of SIVmac239Δnef vaccine induced protection
Published in The Journal of immunology (1950) (01-05-2017)“…Vaccination with live-attenuated SIVmac239Δnef protects most animals challenged with a pathogenic SIV. In this model, there is a maturation of protection which…”
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6
Distribution and phenotype of HIV-specific CD8 T cells in situ in the rectal mucosa of HIV+ elite controllers
Published in The Journal of immunology (1950) (01-05-2017)“…Mucosal tissues including the gastrointestinal tract are important reservoirs for HIV replication. HIV-specific CD8 T cells are essential in controlling HIV…”
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Comparison of Vibratome and Compresstome sectioning of fresh primate lymphoid and genital tissues for in situ MHC-tetramer and immunofluorescence staining
Published in Biological procedures online (07-01-2015)“…For decades, the Vibratome served as a standard laboratory resource for sectioning fresh and fixed tissues. In skilled hands, high quality and consistent fresh…”
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Location and Dynamics of the Immunodominant CD8 T Cell Response to SIV[DELTA]nef Immunization and SIVmac251 Vaginal Challenge
Published in PloS one (09-12-2013)“…Live-attenuated SIV vaccines (LAVs) have been the most effective to date in preventing or partially controlling infection by wild-type SIV in non-human primate…”
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9
Compartmentalization of SIV Replication Within Secondary Lymphoid Tissues of Rhesus Macaques is Linked to Disease Stage and Inversely Related to Localization of Virus-Specific CTL1 2
Published in The Journal of immunology (1950) (31-10-2014)“…We previously demonstrated that HIV replication is concentrated in lymph node B cell follicles during chronic infection and that HIV-specific CTL fail to…”
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Journal Article -
10
Location and Dynamics of the Immunodominant CD8 T Cell Response to SIV Delta nef Immunization and SIVmac251 Vaginal Challenge: e81623
Published in PloS one (01-12-2013)“…Live-attenuated SIV vaccines (LAVs) have been the most effective to date in preventing or partially controlling infection by wild-type SIV in non-human primate…”
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