Search Results - "Wagsater, Dick"

PDGF-C and PDGF-D signaling in vascular diseases and animal models by Folestad, Erika, Kunath, Anne, Wågsäter, Dick

“…Members of the platelet-derived growth factor (PDGF) family are well known to be involved in different pathological conditions. The cellular and molecular…”
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Inflammatory cells, ceramides, and expression of proteases in perivascular adipose tissue adjacent to human abdominal aortic aneurysms by Folkesson, Maggie, PhD, Vorkapic, Emina, MSc, Gulbins, Erich, MD, Japtok, Lukasz, PhD, Kleuser, Burkhard, PhD, Welander, Martin, MD, Länne, Toste, MD, Wågsäter, Dick, PhD

“…Background Abdominal aortic aneurysm (AAA) is a deadly irreversible weakening and distension of the abdominal aortic wall. The pathogenesis of AAA remains…”
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Significant changes in circulating microRNA by dietary supplementation of selenium and coenzyme Q10 in healthy elderly males. A subgroup analysis of a prospective randomized double-blind placebo-controlled trial among elderly Swedish citizens by Alehagen, Urban, Johansson, Peter, Aaseth, Jan, Alexander, Jan, Wågsäter, Dick

“…Selenium and coenzyme Q10 is essential for important cellular functions. A low selenium intake is reported from many European countries, and the endogenous…”
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Screening of circulating microRNA biomarkers for prevalence of abdominal aortic aneurysm and aneurysm growth by Wanhainen, Anders, Mani, Kevin, Vorkapic, Emina, De Basso, Rachel, Björck, Martin, Länne, Toste, Wågsäter, Dick

“…Abstract Background and aims MicroRNA (miR) are important regulators of gene expression and biological processes and have recently been suggested as possible…”
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Emerging role and clinical implication of mRNA scavenger decapping enzyme in colorectal cancer by Jan Dimberg, Shamoun, Levar, Johansson, Gustaf, Landerholm, Kalle, Wågsäter, Dick

“…Turnover of RNA is a regulated process that in part controls gene expression. This process is partly controlled by the scavenger decapping enzyme (DcpS). This…”
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Association of Clinicopathological Factors With MMP13 (rs2252070) Gene Polymorphism in Swedish Patients With Colorectal Cancer by VAN Nguyen, Song, Shamoun, Levar, Landerholm, Kalle, Wågsäter, Dick, Dimberg, Jan

“…Matrix metalloproteinase 13 (MMP13) has been reported to be involved in tumor development and progression, including of colorectal cancer (CRC). This study…”
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Genetic Variants of the IL2 Gene Related to Risk and Survival in Patients With Colorectal Cancer by Dimberg, Jan, Shamoun, Levar, Landerholm, Kalle, Andersson, Roland E, Kolodziej, Blanka, Wågsäter, Dick

“…Interleukin 2 (IL2) is a significant factor activating T-cell-mediated immune response by stimulation of natural killer cells, T-cells and in development of…”
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Metformin Prescription Associated with Reduced Abdominal Aortic Aneurysm Growth Rate and Reduced Chemokine Expression in a Swedish Cohort by Unosson, Jon, Wågsäter, Dick, Bjarnegård, Niclas, De Basso, Rachel, Welander, Martin, Mani, Kevin, Gottsäter, Anders, Wanhainen, Anders

“…Recent reports suggest that the negative association between diabetes mellitus and abdominal aortic aneurysm (AAA) may be driven by metformin, the world's most…”
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Association study on IL-4, IL-4Rα and IL-13 genetic polymorphisms in Swedish patients with colorectal cancer by Shamoun, Levar, Skarstedt, Marita, Andersson, Roland E., Wågsäter, Dick, Dimberg, Jan

“…Interleukin 4 (IL-4) and interleukin 13 (IL-13) are anti-inflammatory and immunomodulatory cytokines which share a common cellular receptor IL4Rα and are…”
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Possible Role and Therapeutic Target of PDGF-D Signalling in Colorectal Cancer by Olsen, Renate Slind, Dimberg, Jan, Geffers, Robert, Wågsäter, Dick

“…Platelet-derived growth factor D (PDGF-D) has been shown to mediate cellular processes of importance in cancer progression. This study aimed to investigate the…”
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Genetic variance and plasma concentration of CD93 is associated with cardiovascular mortality: Results from a 6.7‑year follow‑up of a healthy community‑living elderly population by Alehagen, Urban, Shamoun, Levar, Wågsäter, Dick

“…Inflammation is one of the fundamental processes in numerous diseases. Cluster of differentiation (CD) 93, a glycoprotein, has been reported to be associated…”
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Clinicopathological and prognostic value of CD44 gene polymorphism (rs187115) in Swedish patients with colorectal cancer by Nguyen, Song Van, Shamoun, Levar, Landerholm, Kalle, Wågsäter, Dick, Dimberg, Jan

“…Cluster of differentiation (CD) 44 plays a crucial role in apoptosis, cell-cell interactions, angiogenesis, metastasis and proliferation. The aim of the…”
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The tyrosine kinase inhibitor Bosutinib does not inhibit angiotensin II-induced abdominal aortic aneurysm: Validation of the importance of PDGFR and c-Kit tyrosine kinases by Imatinib by Balboa Ramilo, Amanda, Becirovic-Agic, Mediha, Petri, Marcelo Heron, Mani, Kevin, Wanhainen, Anders, Wågsäter, Dick

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Proteolytically active ADAM10 and ADAM17 carried on membrane microvesicles in human abdominal aortic aneurysms by Folkesson, Maggie, Li, Chunjun, Frebelius, Siw, Swedenborg, Jesper, Wågsäter, Dick, Williams, Kevin Jon, Eriksson, Per, Roy, Joy, Liu, Ming-Ling

“…The intraluminal thrombus (ILT) of human abdominal aortic aneurysm (AAA) has been suggested to damage the underlying aortic wall, but previous work found scant…”
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Endurance exercise activates matrix metalloproteinases in human skeletal muscle by Rullman, Eric, Norrbom, Jessica, Stromberg, Anna, Wagsater, Dick, Rundqvist, Helene, Haas, Tara, Gustafsson, Thomas

“…1 Division of Clinical Physiology, Department of Laboratory Medicine, Karolinska University Hospital, Karolinska Institute, Stockholm; 2 Department of…”
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Circulating inflammatory factors associated with worse long-term prognosis in colorectal cancer by Olsen, Renate S, Nijm, Johnny, Andersson, Roland E, Dimberg, Jan, Wågsäter, Dick

“…AIM To investigate association of circulating inflammatory factors at the time of colorectal cancer(CRC) surgery with survival.METHODS Plasma levels from 174…”
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miR-10b promotes aortic aneurysm formation and aortic rupture in angiotensin II-induced ApoE-deficient mice by Wågsäter, Dick, Ramilo, Amanda Balboa, Näsström, Mikaela, Kunath, Anne, Agic, Mediha Becirovic, Mani, Kevin, Wanhainen, Anders, Petri, Marcelo Heron

“…Abdominal aortic aneurysm (AAA) is associated with increased plasma levels of microRNA (miR) -10b. 5 nmols of miR-10b or miR control was administrated to…”
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Association of gene and protein expression and genetic polymorphism of CC chemokine ligand 4 in colorectal cancer by Shamoun, Levar, Landerholm, Kalle, Balboa Ramilo, Amanda, Andersson, Roland E, Dimberg, Jan, Wågsäter, Dick

“…Leukocytes, such as T cells and macrophages, play an important role in tumorigenesis. CC chemokine ligand (CCL) 4, which is produced by lymphocytes and…”
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Increased mortality in the A/A genotype of the SNP rs28372698 of interleukin 32 by Alehagen, Urban, Shamoun, Levar, Dimberg, Jan Ingvar, Wågsäter, Dick

“…One of the major causes of mortality in the western hemisphere is cardiovascular disease. Therefore, a variety of markers to identify those at risk are…”
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Imatinib treatment attenuates growth and inflammation of angiotensin II induced abdominal aortic aneurysm by Vorkapic, Emina, Dugic, Elma, Vikingsson, Svante, Roy, Joy, Mäyränpää, Mikko I, Eriksson, Per, Wågsäter, Dick

“…Abstract Background Abdominal aortic aneurysm (AAA) is characterized by vascular remodeling with increased infiltration of inflammatory cells and…”
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