Search Results - "Wagnieres, G."

Detection of early cancers by endoscopic fluorescence imaging by Wagnieres, G

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Photodetection of early human bladder cancer based on the fluorescence of 5-aminolaevulinic acid hexylester-induced protoporphyrin IX: a pilot study by LANGE, N, JICHLINSKI, P, ZELLWEGER, M, FORRER, M, MARTI, A, GUILLOU, L, KUCERA, P, WAGNIERES, G, VAN DEN BERGH, H

“…Exogenous administration of 5-aminolaevulinic acid (ALA) is becoming widely used to enhance the endogenous synthesis of protoporphyrin IX (PpIX) in…”
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Photothrombic activity of m-THPC-loaded liposomal formulations: Pre-clinical assessment on chick chorioallantoic membrane model by Pegaz, B., Debefve, E., Ballini, J.-P., Wagnières, G., Spaniol, S., Albrecht, V., Scheglmann, D.V., Nifantiev, N.E., van den Bergh, H., Konan-Kouakou, Y.N.

“…The objective of this study was to evaluate the ability of meso-tetra(hydroxyphenyl)chlorin (m-THPC) encapsulated into liposomal formulations to occlude…”
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Red and NIR light dosimetry in the human deep brain by Pitzschke, A, Lovisa, B, Seydoux, O, Zellweger, M, Pfleiderer, M, Tardy, Y, Wagnières, G

“…Photobiomodulation (PBM) appears promising to treat the hallmarks of Parkinson's Disease (PD) in cellular or animal models. We measured light propagation in…”
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Design of an endoscopic optical reference to be used for autofluorescence bronchoscopy with a commercially available diagnostic autofluorescence endoscopy (DAFE) system by Gabrecht, T, Lovisa, B, Borle, F, Wagnières, G

“…We present the design of a sterilizable optical reference to characterize and quantify the inter-patient variations in tissue autofluorescence during…”
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Photodynamic diagnosis of ovarian cancer using hexaminolaevulinate: a preclinical study by LÜDICKE, F, GABRECHT, T, LANGE, N, WAGNIERES, G, VAN DEN BERGH, H, BERCLAZ, L, MAJOR, A. L

“…The unfailing detection of micrometastases during surgery of patients suffering from ovarian cancer is mandatory for the optimal management of this disease…”
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Low dose endoluminal photodynamic therapy improves murine T cell-mediated colitis by Favre, L, Borle, F, Velin, D, Bachmann, D, Bouzourene, H, Wagnieres, G, van den Bergh, H, Ballabeni, P, Gabrecht, T, Michetti, P, Schreiber, S, Ortner, M-A

“…Low dose photodynamic therapy (LDPDT) may modify the mucosal immune response and may thus provide a therapy for Crohn's disease. We evaluated the efficacy and…”
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A New Drug-Screening Procedure for Photosensitizing Agents Used in Photodynamic Therapy for CNV by Lange, Norbert, Ballini, Jean-Pierre, Wagnieres, Georges, van den Bergh, Hubert

“…Because vascular occlusion has been observed as a consequence of photodynamic therapy (PDT), this method has been successfully used for the treatment of…”
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Endoscopic fluorescence detection of intraepithelial neoplasia in Barrett's esophagus after oral administration of aminolevulinic acid by Stepinac, T, Felley, C, Jornod, P, Lange, N, Gabrecht, T, Fontolliet, C, Grosjean, P, vanMelle, G, van den Bergh, H, Monnier, P, Wagnières, G, Dorta, G

“…Barrett's esophagus is strongly associated with adenocarcinoma. Early malignant transformation of the Barrett's mucosa is often not visible endoscopically and…”
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Photodynamic therapy of early squamous cell carcinomas of the esophagus: a review of 31 cases by Savary, J F, Grosjean, P, Monnier, P, Fontolliet, C, Wagnieres, G, Braichotte, D, van den Bergh, H

“…Patients with cancers of the head and neck have a strong tendency to develop early synchronous and metachronous carcinomas of the esophagus. In many of these…”
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Clinical photodynamic therapy for superficial cancer in the oesophagus and the bronchi: 514 nm compared with 630 nm light irradiation after sensitization with Photofrin II by GROSJEAN, P, WAGNIERES, G, FONTOLLIET, C, VAN DEN BERGH, H, MONNIER, P

“…Photodynamic therapy (PDT) for cancer in the oesophagus and bronchi with red (630 nm) light may occasionally lead to wall perforation and fistula. Therefore,…”
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Preclinical Evaluation of a Novel Water‐soluble Chlorin E 6 Derivative (BLC 1010) as Photosensitizer for the Closure of the Neovessels by Pegaz, B., Debefve, E., Borle, F., Ballini, J.‐P., Wagnières, G., Spaniol, S., Albrecht, V., Scheglmann, D., Nifantiev, N. E., van den Bergh, H., Konan, Y. N.

“…In the present study, photodynamic activity of a novel photosensitizer (PS), Chlorin e 6 ‐2.5 N ‐methyl‐ d ‐glucamine (BLC 1010), was evaluated using the…”
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Determination of tissue optical properties by steady-state spatial frequency-domain reflectometry by D gnitz, N., Wagni res, G.

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Production of the free radicals O .-2 and .OH by irradiation of the photosensitizer zinc(II) phthalocyanine by Hadjur, C., Wagnières, G., Ihringer, F., Monnier, Ph, van den Bergh, H.

“…Zinc(II) phthalocyanine (ZnPC) is a new photosensitizer currently undergoing phase I and II clinical trials at Lausanne's CHUV hospital for the photodynamic…”
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Immunophotodiagnosis of Colon Carcinomas in Patients Injected with Fluoresceinated Chimeric Antibodies Against Carcinoembryonic Antigen by Folli, S., Wagnieres, G., Pelegrin, A., J. -M. Calmes, Braichotte, D., Buchegger, F., Chalandon, Y., Hardman, N., Ch. Heusser, J.-C. Givel, Chapuis, G., Chatelain, A., van den Bergh, H., J.-P. Mach

“…Based on previous experiments in nude mice, showing that fluoresceinated monoclonal antibodies against carcinoembryonic antigen localized specifically in human…”
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Long circulating half‐life and high tumor selectivity of the photosensitizer meta‐tetrahydroxyphenylchlorin conjugated to polyethylene glycol in nude mice grafted with a human colon carcinoma by Westermann, Patrick, Glanzmann, Thomas, Andrejevic, Snezana, Braichotte, Daniel R., Forrer, Martin, Wagnieres, Georges A., Monnier, Philippe, van den Bergh, Hubert, Mach, Jean‐Pierre, Folli, Silvio

“…In a model of nude mice bearing a human colon carcinoma xenograft, the biodistribution and tumor localization of meta‐tetrahydroxyphenylchlorin (m‐THPC)…”
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In Vivo Fluorescence Spectroscopy and Imaging for Oncological Applications by Wagnieres, Georges A., Star, Willem M., Wilson, Brian C.

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Clinical pharmacokinetic studies of photofrin by fluorescence spectroscopy in the oral cavity, the esophagus, and the bronchi by Braichotte, D R, Wagnières, G A, Bays, R, Monnier, P, van den Bergh, H E

“…To optimize photodynamic therapy (PDT) and photodetection of cancer, two important variables that must be considered are the uptake of the dye and the dye…”
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Influence of the protoporphyrin IX photoproducts on tissue oxygenation measurements performed by time-resolved delayed fluorescence spectroscopy in vivo by Huntosova, V, Gerelli, E, Zellweger, M, Wagnières, G

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Yeast as a model organism for endogenous Protoporphyrin IX production by Joniová, J, Gerelli, E, Wagnières, G

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