Search Results - "Wagner, Oliver I"

Synaptic scaffolding protein SYD-2 clusters and activates kinesin-3 UNC-104 in C. elegans by Wagner, Oliver I, Esposito, Alessandro, Köhler, Barbara, Chen, Chih-Wei, Shen, Che-Piao, Wu, Gong-Her, Butkevich, Eugenia, Mandalapu, Sailaja, Wenzel, Dirk, Wouters, Fred S, Klopfenstein, Dieter R

“…Kinesin-3 motor UNC-104/KIF1A is essential for transporting synaptic precursors to synapses. Although the mechanism of cargo binding is well understood, little…”
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Tau/PTL-1 associates with kinesin-3 KIF1A/UNC-104 and affects the motor's motility characteristics in C. elegans neurons by Tien, Nai-Wen, Wu, Gong-Her, Hsu, Chih-Chun, Chang, Chien-Yu, Wagner, Oliver I

“…Abstract Tauopathies are neurodegenerative diseases based on pathological tau-aggregation including Alzheimer's disease, frontotemporal dementia (FTD) and…”
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Loss of intermediate filament IFB‐1 reduces mobility, density, and physiological function of mitochondria in Caenorhabditis elegans sensory neurons by Barmaver, Syed Nooruzuha, Muthaiyan Shanmugam, Muniesh, Chang, Yen, Bayansan, Odvogmed, Bhan, Prerana, Wu, Gong‐Her, Wagner, Oliver I.

“…Mitochondria and intermediate filament (IF) accumulations often occur during imbalanced axonal transport leading to various types of neurological diseases. It…”
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Toxic Effects of Size-tunable Gold Nanoparticles on Caenorhabditis elegans Development and Gene Regulation by Hu, Chun-Chih, Wu, Gong-Her, Lai, Sheng-Feng, Muthaiyan Shanmugam, Muniesh, Hwu, Y., Wagner, Oliver I., Yen, Ta-Jen

“…We utilized size-tunable gold nanoparticles (Au NPs) to investigate the toxicogenomic responses of the model organism Caenorhabditis elegans . We demonstrated…”
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Uptake of TiO2 Nanoparticles into C. elegans Neurons Negatively Affects Axonal Growth and Worm Locomotion Behavior by Hu, Chun-Chih, Wu, Gong-Her, Hua, Tzu-En, Wagner, Oliver I, Yen, Ta-Jen

“…We employ model organism Caenorhabditis elegans to effectively study the toxicology of anatase and rutile phase titanium dioxide (TiO2) nanoparticles (NPs)…”
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Characterization of TAG‐63 and its role on axonal transport in C. elegans by Bhan, Prerana, Muthaiyan Shanmugam, Muniesh, Wang, Ding, Bayansan, Odvogmed, Chen, Chih‐Wei, Wagner, Oliver I.

“…Model organisms are increasingly used to study and understand how neurofilament (NF)‐based neurological diseases develop. However, whether a NF homolog exists…”
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Uptake of TiO 2 Nanoparticles into C. elegans Neurons Negatively Affects Axonal Growth and Worm Locomotion Behavior by Hu, Chun-Chih, Wu, Gong-Her, Hua, Tzu-En, Wagner, Oliver I, Yen, Ta-Jen

“…We employ model organism Caenorhabditis elegans to effectively study the toxicology of anatase and rutile phase titanium dioxide (TiO ) nanoparticles (NPs)…”
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Softness, strength and self-repair in intermediate filament networks by Wagner, Oliver I., Rammensee, Sebastian, Korde, Neha, Wen, Qi, Leterrier, Jean-Francois, Janmey, Paul A.

“…One cellular function of intermediate filaments is to provide cells with compliance to small deformations while strengthening them when large stresses are…”
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Insights on UNC‐104‐dynein/dynactin interactions and their implications on axonal transport in Caenorhabditis elegans by Chen, Chih‐Wei, Peng, Yu‐Fei, Yen, Ying‐Cheng, Bhan, Prerana, Muthaiyan Shanmugam, Muniesh, Klopfenstein, Dieter R., Wagner, Oliver I.

“…Bidirectional cargo transport in neurons can be explained by two models: the “tug‐of‐war model” for short‐range transport, in which several kinesin and dynein…”
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Intramolecular regulation of presynaptic scaffold protein SYD-2/liprin-α by Chia, Poh Hui, Patel, Maulik R., Wagner, Oliver I., Klopfenstein, Dieter R., Shen, Kang

“…SYD-2/liprin-α is a multi-domain protein that associates with and recruits multiple active zone molecules to form presynaptic specializations. Given SYD-2's…”
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Precise Control of Intracellular Trafficking and Receptor-Mediated Endocytosis in Living Cells and Behaving Animals by Chen, Shiau-Chi, Zeng, Neng-Jie, Liu, Grace Y, Wang, Hsien-Chu, Lin, Tzu-Ying, Tai, Yi-Ling, Chen, Chiao-Yun, Fang, Yin, Chuang, Yi-Chien, Kao, Ching-Lin, Cheng, Hsuan, Wu, Bing-Huang, Sun, Pin-Chiao, Bayansan, Odvogmed, Chiu, Yu-Ting, Shih, Chi-Hsuan, Chung, Wen-Hong, Yang, Jia-Bin, Wang, Lily Hui-Ching, Chiang, Po-Han, Chen, Chun-Hao, Wagner, Oliver I, Wang, Yi-Ching, Lin, Yu-Chun

“…Intracellular trafficking, an extremely complex network, dynamically orchestrates nearly all cellular activities. A versatile method that enables the…”
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The interaction of neurofilaments with the microtubule motor cytoplasmic dynein by Wagner, Oliver I, Ascaño, Jennifer, Tokito, Mariko, Leterrier, Jean-Francois, Janmey, Paul A, Holzbaur, Erika L F

“…Neurofilaments are synthesized in the cell body of neurons and transported outward along the axon via slow axonal transport. Direct observation of…”
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