Search Results - "Wagner, F. E."

Functions of AP1 (Fos/Jun) in bone development by Wagner, E F

“…Genetically modified mice and cells have provided important insights into the biological functions of the dimeric transcription factor complex AP1, in…”
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The AP-1 transcription factor JunB is essential for multiple myeloma cell proliferation and drug resistance in the bone marrow microenvironment by Fan, F, Bashari, M H, Morelli, E, Tonon, G, Malvestiti, S, Vallet, S, Jarahian, M, Seckinger, A, Hose, D, Bakiri, L, Sun, C, Hu, Y, Ball, C R, Glimm, H, Sattler, M, Goldschmidt, H, Wagner, E F, Tassone, P, Jaeger, D, Podar, K

“…Despite therapeutic advances, multiple myeloma (MM) remains an incurable disease, predominantly because of the development of drug resistance. The activator…”
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The transcription factor c-JUN/AP-1 promotes HBV-related liver tumorigenesis in mice by Trierweiler, C, Hockenjos, B, Zatloukal, K, Thimme, R, Blum, H E, Wagner, E F, Hasselblatt, P

“…Hepatocellular carcinoma (HCC) develops as a consequence of chronic inflammatory liver diseases such as chronic hepatitis B virus (HBV) infection. The…”
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Loss of JUNB/AP-1 promotes invasive prostate cancer by Thomsen, M K, Bakiri, L, Hasenfuss, S C, Wu, H, Morente, M, Wagner, E F

“…Prostate cancer is a frequent cause of male death in the Western world. Relatively few genetic alterations have been identified, likely owing to disease…”
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Reprogramming activity of NANOGP8, a NANOG family member widely expressed in cancer by Palla, A R, Piazzolla, D, Abad, M, Li, H, Dominguez, O, Schonthaler, H B, Wagner, E F, Serrano, M

“…NANOG is a key transcription factor for pluripotency in embryonic stem cells. The analysis of NANOG in human cells is confounded by the presence of multiple…”
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Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress by Shatirishvili, M, Burk, A S, Franz, C M, Pace, G, Kastilan, T, Breuhahn, K, Hinterseer, E, Dierich, A, Bakiri, L, Wagner, E F, Ponta, H, Hartmann, T N, Tanaka, M, Orian-Rousseau, V

“…CD44, a large family of transmembrane glycoproteins, plays decisive roles in physiological and pathological conditions. CD44 isoforms are involved in several…”
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Mössbauer study of iron gall inks on historical documents by Lerf, A., Wagner, F. E., Dreher, M., Espejo, T., Pérez-Rodríguez, J.-L.

“…Iron gall ink was used in the Western world as a permanent writing material already in late Roman times and throughout the Middle Ages, until it became…”
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Interstitial lung disease induced by gefitinib and Toll-like receptor ligands is mediated by Fra-1 by Takada, Y, Gresh, L, Bozec, A, Ikeda, E, Kamiya, K, Watanabe, M, Kobayashi, K, Asano, K, Toyama, Y, Wagner, E F, Matsuo, K

“…The role of the AP-1 transcription factor Fra-1 (encoded by Fosl1 ) in inflammatory responses associated with lung disease is largely unknown. Here, we show…”
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Bone development and inflammatory disease is regulated by AP-1 (Fos/Jun) by Wagner, E F

“…The Fos and Jun proteins are members of the AP-1 transcription factor complex, which is a central regulator for many cellular functions. This paper summarises…”
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Antagonistic control of cell fates by JNK and p38-MAPK signaling by Wada, T, Stepniak, E, Hui, L, Leibbrandt, A, Katada, T, Nishina, H, Wagner, E F, Penninger, J M

“…During the development and organogenesis of all multicellular organisms, cell fate decisions determine whether cells undergo proliferation, differentiation, or…”
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Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation by Behrens, Axel, Sibilia, Maria, Wagner, Erwin F

“…c-Jun is a major component of the heterodimeric transcription factor AP-1 and is essential for embryonic development, as fetuses lacking Jun die at…”
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Targeting c-Jun and JunB proteins as potential anticancer cell therapy by Gurzov, E N, Bakiri, L, Alfaro, J M, Wagner, E F, Izquierdo, M

“…The activating protein-1 transcription factor, in particular the Jun proteins play critical roles in the regulation of cell proliferation and tumor…”
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Before striking gold in gold-ruby glass by Wagner, F. E, Haslbeck, S, Stievano, L, Calogero, S, Pankhurst, Q. A, Martinek, K. -P

“…The red colour of gold-ruby glass is caused by small particles of metallic gold that form when the gold-containing colourless glass is annealed. But the…”
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AP-1--Introductory remarks by Wagner, E F

“…This issue attempts to give a 'state of the art' overview of the AP-1 transcription factor family, a fundamental class of transcriptional regulators. The AP-1…”
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Strain-Dependent Epithelial Defects in Mice Lacking the EGF Receptor by Sibilia, Maria, Wagner, Erwin F.

“…Mice and cells lacking the epidermal growth factor receptor (EGFR) were generated to examine its physiological role in vivo. Mutant fetuses are retarded in…”
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Magnetism of the chromium thio-spinels Fe1-xCuxCr2S4 studied using muon spin rotation and relaxation by Kalvius, G M, Krimmel, A, Wäppling, R, Hartmann, O, Litterst, F J, Wagner, F E, Tsurkan, V, Loidl, A

“…Powder samples of Fe1-xCuxCr2S4 with x = 0,0.2,0.5,0.8 were studied, between 5 and 300 K. The results reveal that for x < 1, the magnetic order in the series…”
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Control of cell cycle progression by c-Jun is p53 dependent by Schreiber, M, Kolbus, A, Piu, F, Szabowski, A, Möhle-Steinlein, U, Tian, J, Karin, M, Angel, P, Wagner, E F

“…The c-jun proto-oncogene encodes a component of the mitogen-inducible immediate-early transcription factor AP-1 and has been implicated as a positive regulator…”
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Functions of Fos phosphorylation in bone homeostasis, cytokine response and tumourigenesis by Bakiri, L, Reschke, M O, Gefroh, H A, Idarraga, M H, Polzer, K, Zenz, R, Schett, G, Wagner, E F

“…Mice lacking c-fos develop osteopetrosis due to a block in osteoclast differentiation. Carboxy-terminal phosphorylation of Fos on serine 374 by ERK1/2 and…”
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Signalling in osteoclasts and the role of Fos/AP1 proteins by Wagner, E F, Matsuo, K

“…The second cytokine, RANKL, was first characterised as a ligand for the osteoclast inhibitory factor osteoprotegerin, a circulating decoy receptor belonging to…”
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Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice by Wutz, A, Theussl, H C, Dausman, J, Jaenisch, R, Barlow, D P, Wagner, E F

“…In the mouse the insulin-like growth factor receptor type 2 gene (Igf2r) is imprinted and maternally expressed. Igf2r encodes a trans-membrane receptor that…”
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