Search Results - "Wagner, Catriona A."

The contribution of neutrophils to CNS autoimmunity by Pierson, Emily R, Wagner, Catriona A, Goverman, Joan M

“…Abstract Multiple sclerosis (MS) is believed to be initiated when myelin-specific T cells infiltrate the central nervous system (CNS), triggering subsequent…”
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The intersection of COVID-19 and autoimmunity by Knight, Jason S, Caricchio, Roberto, Casanova, Jean-Laurent, Combes, Alexis J, Diamond, Betty, Fox, Sharon E, Hanauer, David A, James, Judith A, Kanthi, Yogendra, Ladd, Virginia, Mehta, Puja, Ring, Aaron M, Sanz, Ignacio, Selmi, Carlo, Tracy, Russell P, Utz, Paul J, Wagner, Catriona A, Wang, Julia Y, McCune, William J

“…Acute COVID-19, caused by SARS-CoV-2, is characterized by diverse clinical presentations, ranging from asymptomatic infection to fatal respiratory failure, and…”
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Rheumatoid Factor as a Potentiator of Anti–Citrullinated Protein Antibody–Mediated Inflammation in Rheumatoid Arthritis by Sokolove, Jeremy, Johnson, Dannette S., Lahey, Lauren J., Wagner, Catriona A., Cheng, Danye, Thiele, Geoffrey M., Michaud, Kaleb, Sayles, Harlan, Reimold, Andreas M., Caplan, Liron, Cannon, Grant W., Kerr, Gail, Mikuls, Ted R., Robinson, William H.

“…Objective The co‐occurrence of rheumatoid factor (RF) and anti–citrullinated protein antibody (ACPA) positivity in rheumatoid arthritis (RA) is well described…”
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Barcode‐Enabled Sequencing of Plasmablast Antibody Repertoires in Rheumatoid Arthritis by Tan, Yann‐Chong, Kongpachith, Sarah, Blum, Lisa K., Ju, Chia‐Hsin, Lahey, Lauren J., Lu, Daniel R., Cai, Xiaoyong, Wagner, Catriona A., Lindstrom, Tamsin M., Sokolove, Jeremy, Robinson, William H.

“…Objective A hallmark of rheumatoid arthritis (RA) is the production of autoantibodies, including anti–citrullinated protein antibodies (ACPAs). Nevertheless,…”
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Neutrophils isolated from systemic lupus erythematosus patients exhibit a distinct functional phenotype by Jog, Neelakshi R, Wagner, Catriona A, Aberle, Teresa, Chakravarty, Eliza F, Arriens, Cristina, Guthridge, Joel M, James, Judith A

“…Neutrophil dysregulation, particularly of a low-density subset, is associated with systemic lupus erythematosus (SLE); however, the exact role of…”
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Serum inflammatory mediators as markers of human Lyme disease activity by Soloski, Mark J, Crowder, Lauren A, Lahey, Lauren J, Wagner, Catriona A, Robinson, William H, Aucott, John N

“…Chemokines and cytokines are key signaling molecules that orchestrate the trafficking of immune cells, direct them to sites of tissue injury and inflammation…”
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Genetic load in incomplete lupus erythematosus by Slief, Matt, Kheir, Joseph M, Smith, Miles, Mowery, Colin, Macwana, Susan, DeJager, Wade, Wagner, Catriona A, Aberle, Teresa, James, Judith A, Guthridge, Joel M

“…Patients with incomplete lupus erythematosus (ILE) have lupus features but insufficient criteria for SLE classification. Some patients with ILE transition to…”
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Serologic markers of Epstein-Barr virus reactivation are associated with increased disease activity, inflammation, and interferon pathway activation in patients with systemic lupus erythematosus by Wood, Rebecca A., Guthridge, Lauren, Thurmond, Emma, Guthridge, Carla J., Kheir, Joseph M., Bourn, Rebecka L., Wagner, Catriona A., Chen, Hua, DeJager, Wade, Macwana, Susan R., Kamp, Stan, Lu, Rufei, Arriens, Cristina, Chakravarty, Eliza F., Thanou, Aikaterini, Merrill, Joan T., Guthridge, Joel M., James, Judith A.

“…SLE is a clinically heterogeneous disease characterized by an unpredictable relapsing-remitting disease course. Although the etiology and mechanisms of SLE…”
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The promise of precision medicine in rheumatology by Guthridge, Joel M., Wagner, Catriona A., James, Judith A.

“…Systemic autoimmune rheumatic diseases (SARDs) exhibit extensive heterogeneity in clinical presentation, disease course, and treatment response. Therefore,…”
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Ancestry-based differences in the immune phenotype are associated with lupus activity by Slight-Webb, Samantha, Thomas, Kevin, Smith, Miles, Wagner, Catriona A, Macwana, Susan, Bylinska, Aleksandra, Donato, Michele, Dvorak, Mai, Chang, Sarah E, Kuo, Alex, Cheung, Peggie, Kalesinskas, Laurynas, Ganesan, Ananthakrishnan, Dermadi, Denis, Guthridge, Carla J, DeJager, Wade, Wright, Christian, Foecke, Mariko H, Merrill, Joan T, Chakravarty, Eliza, Arriens, Cristina, Maecker, Holden T, Khatri, Purvesh, Utz, Paul J, James, Judith A, Guthridge, Joel M

“…Systemic lupus erythematosus (SLE) affects 1 in 537 Black women, which is >2-fold more than White women. Black patients develop the disease at a younger age,…”
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Novel Insights and Therapeutics in Multiple Sclerosis [version 1; peer review: 3 approved] by Wagner, Catriona A, Goverman, Joan M

“…The last twelve years have witnessed the development of new therapies for relapsing-remitting multiple sclerosis that demonstrate increased efficacy relative…”
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Pathogenic T cell cytokines in multiple sclerosis by Wagner, Catriona A, Roqué, Pamela J, Goverman, Joan M

“…Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous system that is believed to have an autoimmune etiology. As MS is the…”
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Myelin-specific CD8+ T cells exacerbate brain inflammation in CNS autoimmunity by Wagner, Catriona A, Roqué, Pamela J, Mileur, Trevor R, Liggitt, Denny, Goverman, Joan M

“…Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the CNS. Although CD4+ T cells are implicated in MS pathogenesis and have been the main…”
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Cutting Edge: Integrin α4 Is Required for Regulatory B Cell Control of Experimental Autoimmune Encephalomyelitis by Glatigny, Simon, Wagner, Catriona A, Bettelli, Estelle

“…The neutralization of integrin α4 (Itga4) is currently used as treatment in multiple sclerosis. Although most studies have focused on its function on…”
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Association of fine specificity and repertoire expansion of anticitrullinated peptide antibodies with rheumatoid arthritis associated interstitial lung disease by Giles, Jon T, Danoff, Sonye K, Sokolove, Jeremy, Wagner, Catriona A, Winchester, Robert, Pappas, Dimitrios A, Siegelman, Stanley, Connors, Geoff, Robinson, William H, Bathon, Joan M

“…Interstitial lung disease (ILD) is associated with high morbidity and mortality in rheumatoid arthritis (RA). Citrullinated proteins are observed in RA lung…”
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Increased inflammation and disease activity among current cigarette smokers with rheumatoid arthritis: a cross-sectional analysis of US veterans by Sokolove, Jeremy, Wagner, Catriona A, Lahey, Lauren J, Sayles, Harlan, Duryee, Michael J, Reimold, Andreas M, Kerr, Gail, Robinson, William H, Cannon, Grant W, Thiele, Geoffrey M, Mikuls, Ted R

“…Cigarette smoking is a major risk factor for RA and has been associated with increased disease severity and lower rates of disease remission. We hypothesized…”
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Correction: Cutting Edge: Integrin α4 Is Required for Regulatory B Cell Control of Experimental Autoimmune Encephalomyelitis by Glatigny, Simon, Wagner, Catriona A., Bettelli, Estelle

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Association of Autoantibody Concentrations and Trajectories With Lupus Nephritis Histologic Features and Treatment Response by Fava, Andrea, Wagner, Catriona A., Guthridge, Carla J., Kheir, Joseph, Macwana, Susan, DeJager, Wade, Gross, Tim, Izmirly, Peter, Belmont, H. Michael, Diamond, Betty, Davidson, Anne, Utz, Paul J., Weisman, Michael H, Magder, Laurence S., Lee, Chun‐Hao, Fine, Derek, Monroy‐Trujillo, Manny, Anolik, Jennifer, Shah, Ummara, Ishimori, Mariko, Clancy, Robert M., Belmont, Michael, Wu, Ming, Bornkamp, Nicole, Putterman, Chaim, Der, Evan, Goilav, Beatrice, Jordan, Nicole, Schwartz, Daniel, Pullman, James, Wofsy, David, Smilek, Dawn, Tosta, Patti, Kretzler, Matthias, Berthier, Celine C., Woodle, E. Steve, Hildeman, Dave, Brenner, Michael, Rao, Deepak, Guthridge, Joel M., Petri, Michelle, Buyon, Jill, James, Judith A.

“…Objective Autoantibodies are a hallmark of lupus nephritis (LN), but their association with LN classes and treatment response are not adequately known. In this…”
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CCL19 as a Chemokine Risk Factor for Posttreatment Lyme Disease Syndrome: a Prospective Clinical Cohort Study by Aucott, John N, Soloski, Mark J, Rebman, Alison W, Crowder, Lauren A, Lahey, Lauren J, Wagner, Catriona A, Robinson, William H, Bechtold, Kathleen T

“…Approximately 10% to 20% of patients optimally treated for early Lyme disease develop persistent symptoms of unknown pathophysiology termed posttreatment Lyme…”
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Identification of anticitrullinated protein antibody reactivities in a subset of anti-CCP-negative rheumatoid arthritis: association with cigarette smoking and HLA-DRB1 'shared epitope' alleles by Wagner, Catriona A, Sokolove, Jeremy, Lahey, Lauren J, Bengtsson, Camilla, Saevarsdottir, Saedis, Alfredsson, Lars, Delanoy, Michelle, Lindstrom, Tamsin M, Walker, Roger P, Bromberg, Reuven, Chandra, Piyanka E, Binder, Steven R, Klareskog, Lars, Robinson, William H

“…A hallmark of rheumatoid arthritis (RA) is the development of autoantibodies targeting proteins that contain citrulline. Anticitrullinated protein antibodies…”
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