Search Results - "Wagger, Jernej"

Regioselective Synthesis of 5- and 3-Hydroxy-N-Aryl-1H-Pyrazole-4-Carboxylates and Their Evaluation as Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase by Vah, Luka, Medved, Tadej, Grošelj, Uroš, Klemenčič, Marina, Podlipnik, Črtomir, Štefane, Bogdan, Wagger, Jernej, Novinec, Marko, Svete, Jurij

“…In silico evaluation of various regioisomeric 5- and 3-hydroxy-substituted alkyl 1-aryl-1H-pyrazole-4-carboxylates and their acyclic precursors yielded…”
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A synthesis of 1-substituted 5-[2-(acylamino)ethyl]-1H-pyrazole-4-carboxamides by KRALJ, David, FRIEDRICH, Miha, GROSELJ, Uros, KIRALY-POTPARA, Sonja, MEDEN, Anton, WAGGER, Jernej, DAHMANN, Georg, STANOVNIK, Branko, SVETE, Jurij

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Synthesis of 3-(2-aminoethyl)-5-hydroxy-1H-pyrazole derivatives by Grošelj, Uroš, Kralj, David, Wagger, Jernej, Dahmann, Georg, Stanovnik, Branko, Svete, Jurij

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Synthesis of ( S, Z)-3-[(1 H-indol-3-yl)methylidene]hexahydropyrrolo[1,2- a]pyrazin-4(1 H)-one: an alternative, enaminone based, route to unsaturated cyclodipeptides by Wagger, Jernej, Grošelj, Uroš, Meden, Anton, Svete, Jurij, Stanovnik, Branko

“…A series of racemic and enantiopure ( S, Z)-3-[(1 H-indol-3-yl)methylidene]hexahydropyrrolo[1,2- a]pyrazin-4(1 H)-one (cyclic Pro–ΔTrp) dipeptide analogues…”
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Tetrahydro-1H,5H-pyrazolo[1,2-a]pyrazole-1-carboxylates as inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase by Strašek, Nika, Lavrenčič, Lara, Oštrek, Andraž, Slapšak, Dejan, Grošelj, Uroš, Klemenčič, Marina, Brodnik Žugelj, Helena, Wagger, Jernej, Novinec, Marko, Svete, Jurij

“…[Display omitted] •Novel 3D-rich scaffold among PfDHODH inhibitors.•Simple synthetic method, broad scope, separable diastereomers.•Separable diastereomers,…”
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[2+2] Cycloaddition of electron-poor acetylenes to ( E)-3-dimethylamino-1-heteroaryl-prop-2-en-1-ones: synthesis of highly functionalized 1-heteroaroyl-1,3-butadienes by Bezenšek, Jure, Koleša, Tanja, Grošelj, Uroš, Wagger, Jernej, Stare, Katarina, Meden, Anton, Svete, Jurij, Stanovnik, Branko

“…Microwave-assisted [2+2] cycloaddition of ( E)-3-dimethylamino-1-heteroaryl-prop-2-en-1-ones to dimethyl acetylenedicarboxylates gives (2 E,3…”
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A Constrained Tricyclic Nucleic Acid Analogue of α‑l‑LNA: Investigating the Effects of Dual Conformational Restriction on Duplex Thermal Stability by Hanessian, Stephen, Wagger, Jernej, Merner, Bradley L, Giacometti, Robert D, Østergaard, Michael E, Swayze, Eric E, Seth, Punit P

“…A constrained tricyclic analogue of α-l-LNA (2), which contains dual modes of conformational restriction about the ribose sugar moiety, has been synthesized…”
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The effect of substituents on the chiral solvating properties of ( S)-1,6-dialkylpiperazine-2,5-diones by Malavašič, Črt, Stanovnik, Branko, Wagger, Jernej, Svete, Jurij

“…The effect of substituents on the chiral solvating properties of 13 different ( S)-1,6-dialkylpiperazine-2,5-diones ( S)- 1a– m and five (3 S,6…”
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Chiral solvating properties of ( S)-1-benzyl-6-methylpiperazine-2,5-dione by Wagger, Jernej, Grdadolnik, Simona Golič, Grošelj, Uroš, Meden, Anton, Stanovnik, Branko, Svete, Jurij

“…In CDCl 3 solution, enantiopure ( S)-1-benzyl-6-methylpiperazine-2,5-dione ( S)- 1a formed diastereomeric C O⋯ H–N hydrogen-bonded associates with racemic (…”
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( S)- N-Benzyl-3(6)-methylpiperazine-2,5-diones as chiral solvating agents for N-acylamino acid esters by Malavašič, Črt, Wagger, Jernej, Stanovnik, Branko, Svete, Jurij

“…Three closely related diketopiperazines, ( S)-1-benzyl-6-methylpiperazine-2,5-dione ( S)- 1a, ( S)-1-benzyl-3-methylpiperazine-2,5-dione ( S)- 1b, and (…”
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Enaminone-Based Synthesis of Dipodazine Derivatives by Wagger, Jernej, Bevk, David, Meden, Anton, Svete, Jurij, Stanovnik, Branko

“…A series of racemic dipodazine analogues 9 were prepared in 22–80% yield from…”
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Synthesis and structure of novel ( S)-1,6-dialkylpiperazine-2,5-diones and (3 S,6 S)-1,3,6-trialkylpiperazine-2,5-diones by Malavašič, Črt, Grošelj, Uroš, Golobič, Amalija, Bezenšek, Jure, Stanovnik, Branko, Stare, Katarina, Wagger, Jernej, Svete, Jurij

“…Eleven ( S)-1,6-dialkylpiperazine-2,5-diones and five (3 S,6 S)-1,3,6-trialkylpiperazine-2,5-diones were prepared in three steps from the corresponding (…”
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A synthesis of 1-substituted 5-[2-(acylamino)ethyl]-1 H-pyrazole-4-carboxamides by Kralj, David, Friedrich, Miha, Grošelj, Uroš, Kiraly-Potpara, Sonja, Meden, Anton, Wagger, Jernej, Dahmann, Georg, Stanovnik, Branko, Svete, Jurij

“…A seven-step synthesis of 1-substituted 5-(2-acylaminoethyl)-1 H-pyrazole-4-carboxamides 20 as the pyrazole analogues of histamine was developed. The synthesis…”
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Parallel Solution-Phase Synthesis of (Z)-3-(Arylamino)-2,3-dehydroalanine Derivatives and Solid-Phase Synthesis of Fused Pyrimidones by Čebašek, Petra, Wagger, Jernej, Bevk, David, Jakše, Renata, Svete, Jurij, Stanovnik, Branko

“…N-Protected (Z)-3-(arylamino)-2,3-dehydroalanine esters 5 and 10 were prepared in one step from methyl (Z)-2-acylamino-3-(dimethylamino)prop-2-enoates 3 and 9…”
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