Search Results - "Waffarn, Elizabeth E."
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Infection-induced type I interferons activate CD11b on B-1 cells for subsequent lymph node accumulation
Published in Nature communications (27-11-2015)“…Innate-like B-1a lymphocytes rapidly redistribute to regional mediastinal lymph nodes (MedLNs) during influenza infection to generate protective IgM. Here we…”
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Protective B cell responses to flu--no fluke
Published in The Journal of immunology (1950) (01-04-2011)“…The mechanisms regulating the induction and maintenance of B lymphocytes have been delineated extensively in immunization studies using proteins and…”
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Human Intestinal Allografts Contain Functional Hematopoietic Stem and Progenitor Cells that Are Maintained by a Circulating Pool
Published in Cell stem cell (07-02-2019)“…Human intestinal transplantation often results in long-term mixed chimerism of donor and recipient blood in transplant patients. We followed the phenotypes of…”
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Natural and induced B-1 cell immunity to infections raises questions of nature versus nurture
Published in Annals of the New York Academy of Sciences (01-12-2015)“…Mouse B‐1 cells are not only major producers of steady‐state natural antibodies but also rapid responders to infections and inflammation. These discrete…”
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Lymphohematopoietic graft-versus-host responses promote mixed chimerism in patients receiving intestinal transplantation
Published in The Journal of clinical investigation (15-04-2021)“…In humans receiving intestinal transplantation (ITx), long-term multilineage blood chimerism often develops. Donor T cell macrochimerism (≥4%) frequently…”
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Rapid thymectomy of NSG mice to analyze the role of native and grafted thymi in humanized mice
Published in European journal of immunology (01-01-2020)“…We developed a rapid method to remove the native mouse thymus from NSG mice, which allowed us to compare the behavior of human immune cells in the presence or…”
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Mixed xenogeneic porcine chimerism tolerizes human anti‐pig natural antibody‐producing cells in a humanized mouse model
Published in Xenotransplantation (Københaven) (01-07-2021)“…Background A major obstacle to the success of organ transplantation from pigs to humans, necessitated by the shortage of human organs, is robust humoral immune…”
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Lymphohematopoietic graft-versus-host responses promote mixed chimerism in patients receiving intestinal transplantation
Published in The Journal of clinical investigation (15-04-2021)“…In humans receiving intestinal transplantation (ITx), long-term multilineage blood chimerism often develops. Donor T cell macrochimerism (>4%) frequently…”
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Journal Article