Search Results - "Wadi, Ishan"

Methylene blue induced morphological deformations in Plasmodium falciparum gametocytes: implications for transmission-blocking by Wadi, Ishan, Pillai, C Radhakrishna, Anvikar, Anupkumar R, Sinha, Abhinav, Nath, Mahendra, Valecha, Neena

“…Malaria remains a global health problem despite availability of effective tools. For malaria elimination, drugs targeting sexual stages of Plasmodium…”
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Investigation of factors affecting the production of P. falciparum gametocytes in an Indian isolate by Wadi, Ishan, Deora, Nimita, Nath, Mahendra, Sinha, Abhinav

“…The fundamental requirement of every gametocytocidal drug screening assay is the sufficient numbers of healthy and viable gametocytes. The number of in vitro…”
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A novel quinoline-appended chalcone derivative as potential Plasmodium falciparum gametocytocide by Kumar, Himank, Wadi, Ishan, Devaraji, Vinod, Pillai, C, Ghosh, Sujit

“…Background & objectives: Malaria has remained a global health problem despite the effective control and treatment measures. In the backdrop of drug resistance,…”
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Recent advances in transmission-blocking drugs for malaria elimination by Wadi, Ishan, Nath, Mahendra, Anvikar, Anupkumar R, Singh, Pargat, Sinha, Abhinav

“…The scientific community worldwide has realized that malaria elimination will not be possible without development of safe and effective transmission-blocking…”
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Synthesis and Antimalarial Evaluation of [1, 2,3]‐Triazole‐Tethered Sulfonamide‐Berberine Hybrids by Batra, Neha, Rajendran, Vinoth, Agarwal, Drishti, Wadi, Ishan, Ghosh, Prahlad C., Gupta, Rinkoo D., Nath, Mahendra

“…Malaria still remains a global health problem despite of the availability of effective control and treatment measures. In the present study, a novel series of…”
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Synthesis and antimalarial activity of 7-chloroquinoline-tethered sulfonamides and their [1,2,3]-triazole hybrids by Batra, Neha, Agarwal, Drishti, Wadi, Ishan, Tekuri, Chandra Sekhar, Gupta, Rinkoo D, Nath, Mahendra

“…Drugs with multiple bioactive moieties have the advantages of multiple modes of action and fewer chances of drug resistance. In continuation of our previous…”
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Malaria transmission-blocking drugs: implications and future perspectives by Wadi, Ishan, Singh, Pargat, Nath, Mahendra, Anvikar, Anupkumar R, Sinha, Abhinav

“…As the world gets closer to eliminating malaria, the scientific community worldwide has begun to realize the importance of malaria transmission-blocking…”
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Targeting Asexual and Sexual Blood Stages of the Human Malaria Parasite P. falciparum with 7‐Chloroquinoline‐Based 1,2,3‐Triazoles by Wadi, Ishan, Prasad, Davinder, Batra, Neha, Srivastava, Kumkum, Anvikar, Anupkumar R., Valecha, Neena, Nath, Mahendra

“…Novel 4‐amino‐7‐chloroquinoline‐based 1,2,3‐triazole hybrids were synthesised in good yields by CuI‐catalysed Huisgen 1,3‐dipolar cycloaddition reactions of…”
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A Model of Interaction Between Apocynin and NADPH Oxidase Enzyme to Analyze the Possible Targets Responsible for Inhibition by Computational Analysis

“…Background/Aims: A multi-component enzyme system called NADPH oxidase (NOX) helps innate immunity by generating reactive oxygen species (ROS). NOX…”
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Critical examination of approaches exploited to assess the effectiveness of transmission-blocking drugs for malaria by Wadi, Ishan, Anvikar, Anupkumar R, Nath, Mahendra, Pillai, C Radhakrishna, Sinha, Abhinav, Valecha, Neena

“…In the absence of clinically proven vaccines and emerging resistance to common antimalarials and insecticides, the onus of interrupting the life cycle of , is…”
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Synthesis, characterization, and antiplasmodial efficacy of sulfonamide‐appended [1,2,3]‐triazoles by Batra, Neha, Rajendran, Vinoth, Wadi, Ishan, Lathwal, Ankit, Dutta, Roshan Kumar, Ghosh, Prahlad C., Gupta, Rinkoo D., Nath, Mahendra

“…A series of benzenesulfonamide‐appended [1,2,3]‐triazole hybrids was synthesized by using [3 + 2] cycloaddition of primary, secondary, and tertiary sulfonamide…”
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Conserved Plasmodium Protein (PF3D7_0406000) of Unknown Function: In-silico Analysis and Cellular Localization by Pandey, Isha, Quadiri, Afshana, Wadi, Ishan, Pillai, C.R., Singh, Agam P., Das, Ashis

“…In spite of a decrease in malaria cases, the threat of malaria due to Plasmodium falciparum still prevails. The sequencing of Plasmodium falciparum reveals…”
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Targeting Asexual and Sexual Blood Stages of Human Malaria Parasite P. falciparum with 7-Chloroquinoline based [1,2,3]-Triazoles by Nath, Mahendra, Wadi, Ishan, Prasad, Davinder, Batra, Neha, Srivastava, Kumkum, Anvikar, Anupkumar R, Valecha, Neena

“…Novel 4-amino-7-chloroquinoline and [1,2,3]-triazole based hybrids were synthesized in good to excellent yields via Cu[I] catalysed Huisgen 1,3-dipolar…”
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