Search Results - "Wadhwa, Pathik D"
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The Interplay Between Nutrition and Stress in Pregnancy: Implications for Fetal Programming of Brain Development
Published in Biological psychiatry (1969) (15-01-2019)“…Growing evidence supports an important role for the intrauterine environment in shaping fetal development and subsequent child health and disease risk. The…”
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Correspondence between hair cortisol concentrations and 30-day integrated daily salivary and weekly urinary cortisol measures
Published in Psychoneuroendocrinology (01-09-2016)“…Highlights • Hair and saliva cortisol concentrations share significant variance. • Hair cortisol concentration is highly stable over time. • Urinary free…”
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Intergenerational Transmission of Maternal Childhood Maltreatment Exposure: Implications for Fetal Brain Development
Published in Journal of the American Academy of Child and Adolescent Psychiatry (01-05-2017)“…Abstract Objective Growing evidence suggests the deleterious consequences of exposure to childhood maltreatment (CM) may not only endure over the exposed…”
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The PedBE clock accurately estimates DNA methylation age in pediatric buccal cells
Published in Proceedings of the National Academy of Sciences - PNAS (22-09-2020)“…The development of biological markers of aging has primarily focused on adult samples. Epigenetic clocks are a promising tool for measuring biological age that…”
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The Contribution of Maternal Stress to Preterm Birth: Issues and Considerations
Published in Clinics in perinatology (01-09-2011)“…Preterm birth represents the most significant problem in maternal–child health, with maternal stress identified as a variable of interest. The effects of…”
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Longitudinal Metabolomic Profiling of Amino Acids and Lipids across Healthy Pregnancy
Published in PloS one (30-12-2015)“…Pregnancy is characterized by a complexity of metabolic processes that may impact fetal development and ultimately, infant health outcomes. However, our…”
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Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood
Published in Proceedings of the National Academy of Sciences - PNAS (16-08-2011)“…Leukocyte telomere length (LTL) is a predictor of age-related disease onset and mortality. The association in adults of psychosocial stress or stress…”
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Effects of pre- and postnatal maternal stress on infant temperament and autonomic nervous system reactivity and regulation in a diverse, low-income population
Published in Development and psychopathology (01-12-2017)“…We examined the prospective associations of objective and subjective measures of stress during pregnancy with infant stress reactivity and regulation, an…”
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Prenatal stress and developmental programming of human health and disease risk: concepts and integration of empirical findings
Published in Current opinion in endocrinology, diabetes, and obesity (01-12-2010)“…The concept of the developmental origins of health and disease susceptibility is rapidly attracting interest and gaining prominence as a complementary approach…”
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Maternal psychosocial stress during pregnancy is associated with newborn leukocyte telomere length
Published in American journal of obstetrics and gynecology (01-02-2013)“…Objective In adults, one of the major determinants of leukocyte telomere length (LTL), a predictor of age-related diseases and mortality, is cumulative…”
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Impaired executive function mediates the association between maternal pre-pregnancy body mass index and child ADHD symptoms
Published in PloS one (15-06-2012)“…Increasing evidence suggests exposure to adverse conditions in intrauterine life may increase the risk of developing attention-deficit/hyperactivity disorder…”
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Ecological momentary assessment of maternal cortisol profiles over a multiple-day period predicts the length of human gestation
Published in Psychosomatic medicine (01-07-2011)“…Biobehavioral models of prenatal stress highlight the importance of the stress-related hormone cortisol. However, the association between maternal cortisol…”
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Maternal pre-pregnancy body mass index is associated with newborn offspring hypothalamic mean diffusivity: a prospective dual-cohort study
Published in BMC medicine (14-02-2023)“…An extensive body of animal literature supports the premise that maternal obesity during pregnancy can alter the development of the fetal hypothalamus (HTH, a…”
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Brown adipose tissue quantification in human neonates using water-fat separated MRI
Published in PloS one (30-10-2013)“…There is a major resurgence of interest in brown adipose tissue (BAT) biology, particularly regarding its determinants and consequences in newborns and…”
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Placental Corticotrophin-Releasing Hormone is a Modulator of Fetal Liver Blood Perfusion
Published in The journal of clinical endocrinology and metabolism (08-03-2021)“…Abstract Context Variation in fetal liver blood flow influences fetal growth and postnatal body composition. Placental corticotrophin-releasing hormone has…”
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Cervicovaginal Microbiome Composition Is Associated with Metabolic Profiles in Healthy Pregnancy
Published in mBio (25-08-2020)“…Microbes and their metabolic products influence early-life immune and microbiome development, yet remain understudied during pregnancy. Vaginal microbial…”
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Etiologic subtypes of attention-deficit/hyperactivity disorder: brain imaging, molecular genetic and environmental factors and the dopamine hypothesis
Published in Neuropsychology review (01-03-2007)“…Multiple theories of Attention-Deficit/Hyper-activity Disorder (ADHD) have been proposed, but one that has stood the test of time is the dopamine deficit…”
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The Effect of a Maternal Mediterranean Diet in Pregnancy on Insulin Resistance is Moderated by Maternal Negative Affect
Published in Nutrients (06-02-2020)“…There is inconsistent evidence that healthy dietary interventions can effectively mitigate the risk of adverse outcomes associated with elevated insulin…”
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Racial or Ethnic and Socioeconomic Inequalities in Adherence to National Dietary Guidance in a Large Cohort of US Pregnant Women
Published in Journal of the Academy of Nutrition and Dietetics (01-06-2017)“…Abstract Background The significance of periconceptional nutrition for optimizing offspring and maternal health and reducing social inequalities warrants…”
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Implications of newborn amygdala connectivity for fear and cognitive development at 6-months-of-age
Published in Developmental cognitive neuroscience (01-04-2016)“…The first year of life is an important period for emergence of fear in humans. While animal models have revealed developmental changes in amygdala circuitry…”
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