Search Results - "Wadensten, Henrik"

Cross-validated Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Quantitation Protocol for a Pharmaceutical Drug and Its Drug-Target Effects in the Brain Using Time-of-Flight and Fourier Transform Ion Cyclotron Resonance Analyzers by Källback, Patrik, Vallianatou, Theodosia, Nilsson, Anna, Shariatgorji, Reza, Schintu, Nicoletta, Pereira, Marcela, Barré, Florian, Wadensten, Henrik, Svenningsson, Per, Andrén, Per E

“…Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) is an established tool in drug development, which enables visualization of…”
Get full text

Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy by Hulme, Heather, Fridjonsdottir, Elva, Gunnarsdottir, Halla, Vallianatou, Theodosia, Zhang, Xiaoqun, Wadensten, Henrik, Shariatgorji, Reza, Nilsson, Anna, Bezard, Erwan, Svenningsson, Per, Andrén, Per E.

“…Neuropeptides are important signalling molecules in the brain and alterations in their expression levels have been linked to neurological disorders such as…”
Get full text

Abnormal structure-specific peptide transmission and processing in a primate model of Parkinson's disease and l -DOPA-induced dyskinesia by Bourdenx, Mathieu, Nilsson, Anna, Wadensten, Henrik, Fälth, Maria, Li, Qin, Crossman, Alan R, Andrén, Per E, Bezard, Erwan

“…Abstract A role for enhanced peptidergic transmission, either opioidergic or not, has been proposed for the generation of l -3,4-dihydroxyphenylalanine ( l…”
Get full text

Differential expression analysis ofEscherichia coli proteins using a novel software for relative quantitation of LC-MS/MS data by Johansson, Carolina, Samskog, Jenny, Sundström, Lars, Wadensten, Henrik, Björkesten, Lennart, Flensburg, John

Get full text

α-synuclein–lipoprotein interactions and elevated ApoE level in cerebrospinal fluid from Parkinson’s disease patients by Paslawskia, Wojciech, Zareba-Paslawskaa, Justyna, Zhanga, Xiaoqun, Hölzla, Katharina, Wadensten, Henrik, Shariatgorji, Mohammadreza, Janelidze, Shorena, Hansson, Oskar, Forsgren, Lars, Andrén, Per E., Svenningsson, Per

“…The progressive accumulation, aggregation, and spread of α-synuclein (αSN) are common hallmarks of Parkinson’s disease (PD) pathology. Moreover, numerous…”
Get full text

Brain Tissue Sample Stabilization and Extraction Strategies for Neuropeptidomics by Fridjonsdottir, Elva, Nilsson, Anna, Wadensten, Henrik, Andrén, Per E

“…Neuropeptides are bioactive peptides that are synthesized and secreted by neurons in signaling pathways in the brain. Peptides and proteins are extremely…”
Get more information

Neurotoxin-Induced Neuropeptide Perturbations in Striatum of Neonatal Rats by Karlsson, Oskar, Kultima, Kim, Wadensten, Henrik, Nilsson, Anna, Roman, Erika, Andrén, Per E, Brittebo, Eva B

“…The cyanobacterial toxin β-N-methylamino-l-alanine (BMAA) is suggested to play a role in neurodegenerative disease. We have previously shown that although the…”
Get full text

Differential expression analysis of Escherichia coli proteins using a novel software for relative quantitation of LC-MS/MS data by Johansson, Carolina, Samskog, Jenny, Sundström, Lars, Wadensten, Henrik, Björkesten, Lennart, Flensburg, John

“…The study of changes in protein levels between samples derived from cells representing different biological conditions is a key to the understanding of…”
Get full text

Facilitated In Vitro Refolding of Human Recombinant Insulin-Like Growth Factor I Using a Solubilizing Fusion Partner by Samuelsson, Elisabet, Wadensten, Henrik, Hartmanis, Maris, Moks, Tomas, Uhlén, Mathias

“…We describe a new approach to refolding recombinant proteins in which an affinity fusion partner, consisting of two IgG-binding domains (ZZ) derived from…”
Get full text

Asymmetry of the endogenous opioid system in the human anterior cingulate: a putative molecular basis for lateralization of emotions and pain by Watanabe, Hiroyuki, Fitting, Sylvia, Hussain, Muhammad Z, Kononenko, Olga, Iatsyshyna, Anna, Yoshitake, Takashi, Kehr, Jan, Alkass, Kanar, Druid, Henrik, Wadensten, Henrik, Andren, Per E, Nylander, Ingrid, Wedell, Douglas H, Krishtal, Oleg, Hauser, Kurt F, Nyberg, Fred, Karpyak, Victor M, Yakovleva, Tatjana, Bakalkin, Georgy

“…Lateralization of the processing of positive and negative emotions and pain suggests an asymmetric distribution of the neurotransmitter systems regulating…”
Get full text

Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB) by De Rosa, Maria, Lu, Lu, Zamaratski, Edouard, Szałaj, Natalia, Cao, Sha, Wadensten, Henrik, Lenhammar, Lena, Gising, Johan, Roos, Annette K., Huseby, Douglas L., Larsson, Rolf, Andrén, Per E., Hughes, Diarmaid, Brandt, Peter, Mowbray, Sherry L., Karlén, Anders

“…[Display omitted] Type I signal peptidases are potential targets for the development of new antibacterial agents. Here we report finding potent inhibitors of…”
Get full text

Extensive Characterization of Tupaia belangeri Neuropeptidome Using an Integrated Mass Spectrometric Approach by Petruzziello, Filomena, Fouillen, Laetitia, Wadensten, Henrik, Kretz, Robert, Andren, Per E, Rainer, Gregor, Zhang, Xiaozhe

“…Neuropeptidomics is used to characterize endogenous peptides in the brain of tree shrews (Tupaia belangeri). Tree shrews are small animals similar to rodents…”
Get full text

Neuropeptide profiling of the bovine hypothalamus: Thermal stabilization is an effective tool in inhibiting post-mortem degradation by Colgrave, Michelle L., Xi, Li, Lehnert, Sigrid A., Flatscher-Bader, Traute, Wadensten, Henrik, Nilsson, Anna, Andren, Per E., Wijffels, Gene

“…The hypothalamus is the central regulatory region of the brain that links the nervous system to the endocrine system via the pituitary gland. It synthesizes…”
Get full text

Correction for Neurotoxin-Induced Neuropeptide Perturbations in Striatum of Neonatal Rats by Karlsson, Oskar, Kultima, Kim, Wadensten, Henrik, Nilsson, Anna, Roman, Erika, Andrén, Per E, Brittebo, Eva B

Get full text

Proteomic profiling of the Baltic Sea cyanobacterium Nodularia spumigena strain AV1 during ammonium supplementation by Vintila, Simina, Jonasson, Sara, Wadensten, Henrik, Nilsson, Anna, Andrén, Per E., El-Shehawy, Rehab

“…The cyanobacterium Nodularia spumigena dominates the annual, toxic summer blooms in the Baltic Sea. Although Nodularia has been receiving attention due to its…”
Get full text

Chemically-Assisted Fragmentation Combined with Multi-Dimensional Liquid Chromatography and Matrix-Assisted Laser Desorption/Ionization Post Source Decay, Matrix-Assisted Laser Desorption/Ionization Tandem Time-of-Flight or Matrix-Assisted Laser Desorption/Ionization Tandem Mass Spectrometry for Improved Sequencing of Tryptic Peptides by Flensburg, John, Tangen, Anders, Prieto, Maria, Hellman, Ulf, Wadensten, Henrik

“…Derivatization of tryptic peptides using an Ettan CAF matrix-assisted laser desorption/ionization (MALDI) sequencing kit in combination with MALDI-post source…”
Get full text

Molecular characterization of native and recombinant apolipoprotein A-IMilano dimer. The introduction of an interchain disulfide bridge remarkably alters the physicochemical properties of apolipoprotein A-I by Calabresi, L, Vecchio, G, Longhi, R, Gianazza, E, Palm, G, Wadensten, H, Hammarström, A, Olsson, A, Karlström, A, Sejlitz, T

“…The disulfide-linked dimer of apolipoprotein A-IMilano (A-IM/A-IM), a natural Arg173-->Cys variant of apoA-I, was purified from carriers' plasma and produced…”
Get full text

Characterization of an extended form of recombinant human insulin-like growth factor II by HAMMARBERG, B, TALLY, M, SAMUELSSON, E, WADENSTEN, H, HOLMGREN, E, HARTMANIS, M, HALL, K, UHLEN, M, MOKS, T

“…To investigate the biological role of variants of human insulin-like growth factor II (IGF-II), an extended form designated IGF-IIE21, with a molecular mass of…”
Get full text