Search Results - "Waddell, Aaron"

CBP/p300: Critical Co-Activators for Nuclear Steroid Hormone Receptors and Emerging Therapeutic Targets in Prostate and Breast Cancers by Waddell, Aaron R, Huang, Haojie, Liao, Daiqing

“…The CREB-binding protein (CBP) and p300 are two paralogous lysine acetyltransferases (KATs) that were discovered in the 1980s-1990s. Since their discovery,…”
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DAXX drives de novo lipogenesis and contributes to tumorigenesis by Mahmud, Iqbal, Tian, Guimei, Wang, Jia, Hutchinson, Tarun E., Kim, Brandon J., Awasthee, Nikee, Hale, Seth, Meng, Chengcheng, Moore, Allison, Zhao, Liming, Lewis, Jessica E., Waddell, Aaron, Wu, Shangtao, Steger, Julia M., Lydon, McKenzie L., Chait, Aaron, Zhao, Lisa Y., Ding, Haocheng, Li, Jian-Liang, Purayil, Hamsa Thayele, Huo, Zhiguang, Daaka, Yehia, Garrett, Timothy J., Liao, Daiqing

“…Cancer cells exhibit elevated lipid synthesis. In breast and other cancer types, genes involved in lipid production are highly upregulated, but the mechanisms…”
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Abstract 1473: Role of acetyltransferases CBP and p300 in de novo fatty acid synthesis in colorectal cancer by Waddell, Aaron, Mahmud, Iqbal, Liao, Daiqing

“…Abstract CBP/p300 are two paralogous lysine acetyltransferases that acetylate protein substrates including histones, and serve as transcriptional co-activators…”
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Abstract 4669: Pharmacologic inhibition of CBP/p300 suppresses estrogen-induced gene expression and proliferation in ER+ luminal breast cancer cells by Waddell, Aaron Richard, Mahmud, Iqbal, Huo, Zhiguang, Liao, Daiqing

“…Abstract Luminal breast cancer, defined by the expression of the estrogen receptor alpha (ERα), comprises nearly two thirds of all breast cancer cases and most…”
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Pharmacological Inhibition of CBP/p300 Blocks Estrogen Receptor Alpha (ERα) Function through Suppressing Enhancer H3K27 Acetylation in Luminal Breast Cancer by Waddell, Aaron, Mahmud, Iqbal, Ding, Haocheng, Huo, Zhiguang, Liao, Daiqing

“…Estrogen receptor alpha (ER) is the oncogenic driver for ER+ breast cancer (BC). ER antagonists are the standard-of-care treatment for ER+ BC; however, primary…”
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Abstract 5214: Targeting the estrogen receptor pathway in luminal breast cancer through inhibition of p300/CBP by Waddell, Aaron, Mahmud, Iqbal, Tian, Guimei, Liao, Daiqing

“…Abstract Luminal breast cancer represents approximately two thirds of all breast cancer cases and is characterized by the expression of hormone receptors, such…”
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p300 KAT Regulates SOX10 Stability and Function in Human Melanoma by Waddell, Aaron, Grbic, Nicole, Leibowitz, Kassidy, Wyant, William Austin, Choudhury, Sabah, Park, Kihyun, Collard, Marianne, Cole, Philip A, Alani, Rhoda M

“…SOX10 is a lineage-specific transcription factor critical for melanoma tumor growth; on the other hand, SOX10 loss-of-function drives the emergence of…”
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Why Human Security Matters—Rethinking Australian Foreign Policy. Sydney—Melbourne—Auckland—London: Allen & Unwin. 232 pages. ISBN 978‐1‐74331‐202‐5. $33.99. edited by DennisAltman, Joseph A.Camilleri, RobynEckersley, & GerhardHoffstaedter (Eds.). 2012 by Waddell, Aaron P.

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Why human security matters: rethinking Australian foreign policy by Waddell, Aaron P, Altman, Dennis, Camilleri, Joseph A, Eckersley, Robyn, Hoffstaedter, Gerhard

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BOOK REVIEW - Why Human Security Matters-Rethinking Australian Foreign Policy by Waddell, Aaron P.

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Why Human Security Matters—Rethinking Australian Foreign Policy. Sydney—Melbourne—Auckland—London: Allen & Unwin. 232 pages. ISBN 978‐1‐74331‐202‐5. $33.99. edited by Dennis Altman , Joseph A. Camilleri , Robyn Eckersley , & Gerhard Hoffstaedter (Eds.). 2012 by Waddell, Aaron P.

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