Search Results - "Wacklin, Hanna P"

Composition and Asymmetry in Supported Membranes Formed by Vesicle Fusion by Wacklin, Hanna P

“…The structure and formation of supported membranes at silica surfaces by vesicle fusion was investigated by neutron reflectivity and quartz crystal…”
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Neutron reflection from supported lipid membranes by Wacklin, Hanna P.

“…Neutron reflection has become a popular tool to study supported lipid membranes, demonstrating the advantages of the structural and compositional insights…”
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New Insights into the Interaction of Class II Dihydroorotate Dehydrogenases with Ubiquinone in Lipid Bilayers as a Function of Lipid Composition by Orozco Rodriguez, Juan Manuel, Wacklin-Knecht, Hanna P, Clifton, Luke A, Bogojevic, Oliver, Leung, Anna, Fragneto, Giovanna, Knecht, Wolfgang

“…The fourth enzymatic reaction in the de novo pyrimidine biosynthesis, the oxidation of dihydroorotate to orotate, is catalyzed by dihydroorotate dehydrogenase…”
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The Antifungal Mechanism of Amphotericin B Elucidated in Ergosterol and Cholesterol-Containing Membranes Using Neutron Reflectometry by Delhom, Robin, Nelson, Andrew, Laux, Valerie, Haertlein, Michael, Knecht, Wolfgang, Fragneto, Giovanna, Wacklin-Knecht, Hanna P

“…We have characterized and compared the structures of ergosterol- and cholesterol-containing 1-palmitoyl-2-oleoyl- -glycero-3-phosphocholine (POPC) membranes…”
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Cyclotides Insert into Lipid Bilayers to Form Membrane Pores and Destabilize the Membrane through Hydrophobic and Phosphoethanolamine-specific Interactions by Wang, Conan K., Wacklin, Hanna P., Craik, David J.

“…Cyclotides are a family of plant-derived circular proteins with potential therapeutic applications arising from their remarkable stability, broad sequence…”
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Neutron reflection study of the interaction of the eukaryotic pore-forming actinoporin equinatoxin II with lipid membranes reveals intermediate states in pore formation by Wacklin, Hanna P., Bremec, Biserka Bakrač, Moulin, Martina, Rojko, Nejc, Haertlein, Michael, Forsyth, Trevor, Anderluh, Gregor, Norton, Raymond S.

“…Equinatoxin II (EqtII), a eukaryotic pore-forming toxin, lyses cell membranes through a mechanism involving the insertion of its N-terminal α-helix into the…”
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Interfacial Mechanism of Phospholipase A2: pH-Dependent Inhibition and Me-β-cyclodextrin Activation by Wacklin, Hanna P

“…The pH-dependent activity of phospholipase A2 (PLA2) from Naja mossambica mossambica venom and the membrane-water partitioning of the lipid hydrolysis products…”
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Fluid and Highly Curved Model Membranes on Vertical Nanowire Arrays by Dabkowska, Aleksandra P, Niman, Cassandra S, Piret, Gaëlle, Persson, Henrik, Wacklin, Hanna P, Linke, Heiner, Prinz, Christelle N, Nylander, Tommy

“…Sensing and manipulating living cells using vertical nanowire devices requires a complete understanding of cell behavior on these substrates. Changes in cell…”
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Spontaneous Formation of Asymmetric Lipid Bilayers by Adsorption of Vesicles by Wacklin, Hanna P, Thomas, Robert K

“…We have investigated the adsorption of phospholipid mixtures using neutron reflection. Small sonicated unilamellar vesicles (SUV) composed of DOPC and d…”
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Distribution of reaction products in phospholipase A2 hydrolysis by Wacklin, Hanna P., Tiberg, Fredrik, Fragneto, Giovanna, Thomas, Robert K.

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Synthesis of Perdeuterated 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine ([D82]POPC) and Characterisation of Its Lipid Bilayer Membrane Structure by Neutron Reflectometry by Yepuri, Nageshwar R., Darwish, Tamim A., Krause-Heuer, Anwen M., Leung, Anna E., Delhom, Robin, Wacklin, Hanna P., Holden, Peter J.

“…1‐Palmitoyl‐2‐oleoyl‐sn‐glycero‐3‐phosphocholine (POPC), an unsaturated acyl chain containing lipid, is often the predominant lipid in eukaryotic cell…”
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Creation of distinctive Bax-lipid complexes at mitochondrial membrane surfaces drives pore formation to initiate apoptosis by Clifton, Luke A, Wacklin-Knecht, Hanna P, Ådén, Jörgen, Mushtaq, Ameeq Ul, Sparrman, Tobias, Gröbner, Gerhard

“…Apotosis is an essential process tightly regulated by the Bcl-2 protein family where proapoptotic Bax triggers cell death by perforating the mitochondrial…”
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Scientific Highlights from FIGARO's First Year by Wacklin, Hanna P., Campbell, Richard A., Cubitt, Robert, Fragneto, Giovanna

“…FIGARO ( http://www.ill.eu/instruments-support/instruments-groups/instruments/figaro/ ) is the ILL's new horizontal time-of-flight neutron reflectometer…”
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The Anti-Apoptotic Bcl-2 Protein Behaves as an Integral Membrane Protein by Ul Mushtaq, Ameeq, Åden, Jörgen, Sparrman, Tobias, Dingeldein, Artur P.G., Wacklin, Hanna P., Clifton, Luke A., Grobner, Gerhard

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Mitochondrial Membranes Involved in Apoptosis - the Bcl-2 Proteins by Åden, Jörgen, Ul Mushtaq, Ameeq, Sparrman, Tobias, Dingeldein, Artur P., Wacklin, Hanna P., Wacklin, Hanna, Clifton, Luke A., Grobner, Gerhard

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Mitochondrial Membrane Organization under Oxidative Stress: Insight by Solid-State NMR and Neutron Reflectometry by Dingeldein, Artur P., Sparrman, Tobias, Åden, Jörgen, Wacklin, Hanna P., Clifton, Luke A., Grobner, Gerhard

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Interfacial Mechanism of Phospholipase A 2 : pH-Dependent Inhibition and Me-β-cyclodextrin Activation by Wacklin, Hanna P.

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Continuous Flow AFM Imaging Reveals Fluidity and Time Dependent Interactions of Antimicrobial Dendrimer with Model Lipid Membranes by Lind, Tania K., Zielinska, Paulina, Wacklin, Hanna P., Urbanczyk-Lipkowska, Zofia, Cárdenas, Marité

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Distribution of reaction products in phospholipase A(2) hydrolysis by Wacklin, Hanna, Tiberg, Fredrik, Fragneto, Giovanna, Thomas, Robert K.

“…We have monitored the composition of supported phospholipid bilayers during phospholipase A(2) hydrolysis using specular neutron reflection and ellipsometry…”
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Distribution of reaction products in phospholipase A 2 hydrolysis by Wacklin, Hanna P., Tiberg, Fredrik, Fragneto, Giovanna, Thomas, Robert K.

“…We have monitored the composition of supported phospholipid bilayers during phospholipase A 2 hydrolysis using specular neutron reflection and ellipsometry…”
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