Search Results - "Wachalska, Magda"
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Non‑invasive prostate cancer detection by measuring miRNA variants (isomiRs) in urine extracellular vesicles
Published in Oncotarget (19-04-2016)“…In many cancer types, the expression and function of ~22 nucleotide-long microRNAs (miRNA) is deregulated. Mature miRNAs can be stably detected in…”
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2
Protein Complexes in Urine Interfere with Extracellular Vesicle Biomarker Studies
Published in Journal of circulating biomarkers (01-01-2016)“…Urine exosomes (extracellular vesicles; EVs) contain (micro)RNA (miRNA) and protein biomarkers that are useful for the non-invasive diagnosis of various…”
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3
Small-molecule correctors divert CFTR-F508del from ERAD by stabilizing sequential folding states
Published in Molecular biology of the cell (01-02-2024)“…Over 80% of people with cystic fibrosis (CF) carry the F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR), a chloride ion…”
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4
UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER
Published in Nature (London) (14-03-2024)“…Reversible modification of target proteins by ubiquitin and ubiquitin-like proteins (UBLs) is widely used by eukaryotic cells to control protein fate and cell…”
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The herpesvirus UL49.5 protein hijacks a cellular C-degron pathway to drive TAP transporter degradation
Published in Proceedings of the National Academy of Sciences - PNAS (12-03-2024)“…The transporter associated with antigen processing (TAP) is a key player in the major histocompatibility class I-restricted antigen presentation and an…”
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The N-terminal Proline Hinge Motif Controls the Structure of Bovine Herpesvirus 1-encoded Inhibitor of the Transporter Associated with Antigen Processing Required for its Immunomodulatory Function
Published in Journal of molecular biology (01-03-2023)“…[Display omitted] •UL49.5 of BoHV-1 inhibits TAP transporter by mechanisms undetermined on a molecular level.•Mutations in 52PPQ54 proline hinge resulted in…”
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Alphaherpesvirus gB Homologs Are Targeted to Extracellular Vesicles, but They Differentially Affect MHC Class II Molecules
Published in Viruses (10-04-2020)“…Herpesvirus envelope glycoprotein B (gB) is one of the best-documented extracellular vesicle (EVs)-incorporated viral proteins. Regarding the sequence and…”
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Palmitoylated mNeonGreen Protein as a Tool for Visualization and Uptake Studies of Extracellular Vesicles
Published in Membranes (Basel) (27-11-2020)“…Extracellular vesicles (EVs) are membranous nanoparticles released by cells as vital mediators of intercellular communication. As such, EVs have become an…”
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Fluorescent TAP as a Platform for Virus-Induced Degradation of the Antigenic Peptide Transporter
Published in Cells (Basel, Switzerland) (07-12-2019)“…Transporter associated with antigen processing (TAP), a key player in the major histocompatibility complex class I-restricted antigen presentation, makes an…”
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10
Protein Complexes in Urine Interfere with Extracellular Vesicle Biomarker Studies
Published in Journal of circulating biomarkers (01-03-2016)“…Abstract non disponibile…”
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