Search Results - "Waard, Vivian"

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    Pregnancy and Thoracic Aortic Disease: Managing the Risks by Wanga, Shaynah, MD, Silversides, Candice, MD, Dore, Annie, MD, de Waard, Vivian, PhD, Mulder, Barbara, MD, PhD

    Published in Canadian journal of cardiology (2016)
    “…Abstract The most common aortopathies in women of childbearing age are bicuspid aortic valve, coarctation of the aorta, Marfan syndrome, Ehlers-Danlos…”
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    S100A9 Links Inflammation and Repair in Myocardial Infarction by Marinković, Goran, Koenis, Duco Steven, de Camp, Lisa, Jablonowski, Robert, Graber, Naomi, de Waard, Vivian, de Vries, Carlie Jacoba, Goncalves, Isabel, Nilsson, Jan, Jovinge, Stefan, Schiopu, Alexandru

    Published in Circulation research (14-08-2020)
    “…RATIONALE:The alarmin S100A9 has been identified as a potential therapeutic target in myocardial infarction. Short-term S100A9 blockade during the inflammatory…”
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    Endothelial dysfunction in Marfan syndrome mice is restored by resveratrol by Mieremet, Arnout, van der Stoel, Miesje, Li, Siyu, Coskun, Evrim, van Krimpen, Tsveta, Huveneers, Stephan, de Waard, Vivian

    Published in Scientific reports (28-12-2022)
    “…Patients with Marfan syndrome (MFS) develop thoracic aortic aneurysms as the aorta presents excessive elastin breaks, fibrosis, and vascular smooth muscle cell…”
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    Microfibril-associated glycoprotein 4 forms octamers that mediate interactions with elastogenic proteins and cells by Wozny, Michael R., Nelea, Valentin, Siddiqui, Iram Fatima S., Wanga, Shaynah, de Waard, Vivian, Strauss, Mike, Reinhardt, Dieter P.

    Published in Nature communications (13-05-2024)
    “…Microfibril-associated glycoprotein 4 (MFAP4) is a 36-kDa extracellular matrix glycoprotein with critical roles in organ fibrosis, chronic obstructive…”
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    Clinical Features Differ Substantially Between Caucasian and Asian Populations of Marfan Syndrome by Franken, Romy, Hartog, Alexander W. den, Riet, Liz van de, Timmermans, Janneke, Scholte, Arthur J., Maarten P. van den Berg, Waard, Vivian de, Zwinderman, Aeilko H., Groenink, Maarten, Yip, James W., Mulder, Barbara J.M.

    Published in Circulation Journal (2013)
    “…Background: Prevention of aortic dissection and sudden death in patients with Marfan syndrome (MFS) requires accurate diagnosis. MFS is diagnosed by the Ghent…”
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    Bone Marrow–Specific Deficiency of Nuclear Receptor Nur77 Enhances Atherosclerosis by Hamers, Anouk A.J, Vos, Mariska, Rassam, Fadi, Marinković, Goran, Kurakula, Kondababu, van Gorp, Patrick J, de Winther, Menno P.J, Gijbels, Marion J.J, de Waard, Vivian, de Vries, Carlie J.M

    Published in Circulation research (03-02-2012)
    “…RATIONALE:Nuclear receptor Nur77, also known as NR4A1, TR3, or NGFI-B, is expressed in human atherosclerotic lesions in macrophages, endothelial cells, T cells…”
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    The Potential Beneficial Effects of Resveratrol on Cardiovascular Complications in Marfan Syndrome Patients⁻Insights from Rodent-Based Animal Studies by van Andel, Mitzi M, Groenink, Maarten, Zwinderman, Aeilko H, Mulder, Barbara J M, de Waard, Vivian

    “…Marfan syndrome (MFS) patients are at risk for cardiovascular disease. In particular, for aortic aneurysm formation, which ultimately can result in a…”
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    A Novel Hypothesis: A Role for Follicle Stimulating Hormone in Abdominal Aortic Aneurysm Development in Postmenopausal Women by Tedjawirja, Victoria N, Nieuwdorp, Max, Yeung, Kak Khee, Balm, Ron, de Waard, Vivian

    Published in Frontiers in endocrinology (Lausanne) (13-10-2021)
    “…An abdominal aortic aneurysm (AAA) is a dilatation of the abdominal aorta, which can potentially be fatal due to exsanguination following rupture. Although AAA…”
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    Nuclear Receptor Nur77 Controls Cardiac Fibrosis through Distinct Actions on Fibroblasts and Cardiomyocytes by Medzikovic, Lejla, Heese, Hylja, van Loenen, Pieter B, van Roomen, Cindy P A A, Hooijkaas, Ingeborg B, Christoffels, Vincent M, Creemers, Esther E, de Vries, Carlie J M, de Waard, Vivian

    “…Fibrosis is a hallmark of adverse cardiac remodeling, which promotes heart failure, but it is also an essential repair mechanism to prevent cardiac rupture,…”
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    6-Mercaptopurine reduces macrophage activation and gut epithelium proliferation through inhibition of GTPase Rac1 by Marinković, Goran, Hamers, Anouk A J, de Vries, Carlie J M, de Waard, Vivian

    Published in Inflammatory bowel diseases (01-09-2014)
    “…Inflammatory bowel disease is characterized by chronic intestinal inflammation. Azathioprine and its metabolite 6-mercaptopurine (6-MP) are effective…”
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    Novel molecular imaging ligands targeting matrix metalloproteinases 2 and 9 for imaging of unstable atherosclerotic plaques by Hakimzadeh, Nazanin, Pinas, Victorine A, Molenaar, Ger, de Waard, Vivian, Lutgens, Esther, van Eck-Smit, Berthe L F, de Bruin, Kora, Piek, Jan J, Eersels, Jos L H, Booij, Jan, Verberne, Hein J, Windhorst, Albert D

    Published in PloS one (30-11-2017)
    “…Molecular imaging of matrix metalloproteinases (MMPs) may allow detection of atherosclerotic lesions vulnerable to rupture. In this study, we develop a novel…”
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    Inadequate detection of the FSHR complicates future research on extragonadal FSHR localization by Tedjawirja, Victoria N, Hooijer, Gerrit K J, Savci-Heijink, C Dilara, Kovac, Kristina, Balm, Ron, de Waard, Vivian

    Published in Frontiers in endocrinology (Lausanne) (16-02-2023)
    “…Recently, follicle stimulating hormone (FSH) through interaction with its receptor (FSHR) has been proposed to play a role in postmenopausal osteoporosis and…”
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