Search Results - "Waaijman, Taco"

Multi-species oral biofilm promotes reconstructed human gingiva epithelial barrier function by Shang, Lin, Deng, Dongmei, Buskermolen, Jeroen Kees, Janus, Marleen Marga, Krom, Bastiaan Philip, Roffel, Sanne, Waaijman, Taco, van Loveren, Cor, Crielaard, Wim, Gibbs, Susan

“…Since the oral mucosa is continuously exposed to abundant microbes, one of its most important defense features is a highly proliferative, thick, stratified…”
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Autocrine Regulation of Re-Epithelialization After Wounding by Chemokine Receptors CCR1, CCR10, CXCR1, CXCR2, and CXCR3 by Kroeze, Kim L., Boink, Mireille A., Sampat-Sardjoepersad, Shakun C., Waaijman, Taco, Scheper, Rik J., Gibbs, Susan

“…This study identifies chemokine receptors involved in an autocrine regulation of re-epithelialization after skin tissue damage. We determined which receptors,…”
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Outcome of Burns Treated With Autologous Cultured Proliferating Epidermal Cells: A Prospective Randomized Multicenter Intrapatient Comparative Trial by Gardien, Kim L M, Marck, Roos E, Bloemen, Monica C T, Waaijman, Taco, Gibbs, Sue, Ulrich, Magda M W, Middelkoop, Esther

“…Standard treatment for large burns is transplantation with meshed split skin autografts (SSGs). A disadvantage of this treatment is that healing is accompanied…”
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Technical Advance: Langerhans cells derived from a human cell line in a full-thickness skin equivalent undergo allergen-induced maturation and migration by Ouwehand, Krista, Spiekstra, Sander W., Waaijman, Taco, Scheper, Rik J., Gruijl, Tanja D., Gibbs, Susan

“…New method to develop a human skin‐equivalent containing LC‐like cells in vitro, under conditions that mimic the natural tissue composition. In this report,…”
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A Multi-Organ-on-Chip Approach to Investigate How Oral Exposure to Metals Can Cause Systemic Toxicity Leading to Langerhans Cell Activation in Skin by Koning, Jasper J, Rodrigues Neves, Charlotte T, Schimek, Katharina, Thon, Maria, Spiekstra, Sander W, Waaijman, Taco, de Gruijl, Tanja D, Gibbs, Susan

“…Investigating systemic toxicity is still a huge challenge. Here, a multi-organ-on-chip approach is presented as a typical case of topical exposure of oral…”
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Human saliva stimulates skin and oral wound healing in vitro by Rodrigues Neves, Charlotte, Buskermolen, Jeroen, Roffel, Sanne, Waaijman, Taco, Thon, Maria, Veerman, Enno, Gibbs, Susan

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Use of a collagen-elastin matrix as transport carrier system to transfer proliferating epidermal cells to human dermis in vitro by Waaijman, Taco, Breetveld, Melanie, Ulrich, Magda, Middelkoop, Esther, Scheper, Rik J, Gibbs, Susan

“…This in vitro study describes a novel cell culture, transport, and transfer protocol that may be highly suitable for delivering cultured proliferating…”
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Comparison of autologous full-thickness gingiva and skin substitutes for wound healing by Vriens, Abraham P, Waaijman, Taco, van den Hoogenband, Henk M, de Boer, Edith M, Scheper, Rik J, Gibbs, Susan

“…Ideally tissue-engineered products should maintain the characteristics of the original tissue. For example, skin represents orthokeratinized epithelium and…”
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Immunologic Purging of Autologous Peripheral Blood Stem Cell Products Based on CD34 and CD133 Expression Can Be Effectively and Safely Applied in Half of the Acute Myeloid Leukemia Patients by FELLER, Nicole, VAN DER POL, Marjolein A, WAAIJMAN, Taco, WEIJERS, Geert W. D, WESTRA, Guus, OSSENKOPPELE, Gert J, SCHUURHUIS, Gerrit J

“…Purpose: Several studies have shown survival benefit by autologous stem cell transplantation in acute myeloid leukemia (AML) after purging of grafts. This has,…”
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Integration of line-field confocal optical coherence tomography and in situ microenvironmental mapping to investigate the living microenvironment of reconstructed human skin and melanoma models by Michielon, Elisabetta, Motta, Alexandre C., Ogien, Jonas, Oranje, Paul, Waaijman, Taco, Thakoersing, Varsha, Veldhorst, Sanne, de Gruijl, Tanja D., Gibbs, Susan

“…In tissue engineering, real-time monitoring of tumors and of the dynamics of the microenvironment within in vitro models has traditionally been hindered by the…”
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Carcinogenic effects of prolonged daily low‐emission phototherapy in psoriasis by Franken, Sylvie Mireille, Spiekstra, Sander Wiebrand, Waaijman, Taco, Lissenberg‐Witte, Birgit, Rustemeyer, Thomas

“…Background Low‐dose UV treatment has been shown to be effective in mild psoriasis. However, the prolonged use of this treatment modality may raise concerns…”
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Monocytes co-cultured with reconstructed keloid and normal skin models skew towards M2 macrophage phenotype by Limandjaja, Grace C., Waaijman, Taco, Roffel, Sanne, Niessen, Frank B., Gibbs, Susan

“…Several abnormalities have been reported in the peripheral blood mononuclear cells of keloid-forming patients and particularly in the monocyte cell fraction…”
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Human saliva stimulates skin and oral wound healing in vitro by Rodrigues Neves, Charlotte, Buskermolen, Jeroen, Roffel, Sanne, Waaijman, Taco, Thon, Maria, Veerman, Enno, Gibbs, Susan

“…Despite continuous exposure to environmental pathogens, injured mucosa within the oral cavity heals faster and almost scar free compared with skin. Saliva is…”
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Micro-environmental cross-talk in an organotypic human melanoma-in-skin model directs M2-like monocyte differentiation via IL-10 by Michielon, Elisabetta, López González, Marta, Burm, Judith L. A., Waaijman, Taco, Jordanova, Ekaterina S., de Gruijl, Tanja D., Gibbs, Susan

“…Preclinical assessment of novel therapies to fight cancer requires models that reflect the human physiology and immune response. Here, we established an in…”
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Environmentally Controlled Microfluidic System Enabling Immune Cell Flow and Activation in an Endothelialised Skin-On-Chip by Michielon, Elisabetta, Boninsegna, Matteo, Waaijman, Taco, Fassini, Dario, Spiekstra, Sander W, Cramer, Jeremy, Gaudriault, Pierre, Kodolányi, János, de Gruijl, Tanja D, Homs-Corbera, Antoni, Gibbs, Susan

“…Integration of reconstructed human skin (RhS) into organ-on-chip (OoC) platforms addresses current limitations imposed by static culturing. This innovation,…”
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Reconstructed human keloid models show heterogeneity within keloid scars by Limandjaja, Grace C., van den Broek, Leonarda J., Waaijman, Taco, Breetveld, Melanie, Monstrey, Stan, Scheper, Rik J., Niessen, Frank B., Gibbs, Susan

“…Keloid scars are often described as having an actively growing peripheral margin with a regressing centre. The aim of this study was to examine the possible…”
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A Reconstructed Human Melanoma-in-Skin Model to Study Immune Modulatory and Angiogenic Mechanisms Facilitating Initial Melanoma Growth and Invasion by Michielon, Elisabetta, López González, Marta, Stolk, Dorian A, Stolwijk, Joeke G C, Roffel, Sanne, Waaijman, Taco, Lougheed, Sinéad M, de Gruijl, Tanja D, Gibbs, Susan

“…Invasion, immune modulation, and angiogenesis are crucial in melanoma progression. Studies based on animals or two-dimensional cultures poorly recapitulate the…”
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Characterization of In Vitro Reconstructed Human Normotrophic, Hypertrophic, and Keloid Scar Models by Limandjaja, Grace C, van den Broek, Lenie J, Breetveld, Melanie, Waaijman, Taco, Monstrey, Stan, de Boer, Edith M, Scheper, Rik J, Niessen, Frank B, Gibbs, Susan

“…To understand scar pathology, develop new drugs, and provide a platform for personalized medicine, physiologically relevant human scar models are required,…”
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Abstract 155: Towards the development of an in vitro human vascularized immunocompetent metastatic melanoma-on-chip model by Michielon, Elisabetta, de GruIijl, Tanja, Waaijman, Taco, Boninsegna, Matteo, Prabhakaran, Divyasree, Mejri, Hadhemi, Corbera, Antoni Homs, Gaudriault, Pierre, Gibbs, Susan, Fassini, Dario

“…Abstract Despite recent extraordinary clinical success of immune checkpoint inhibitors (ICIs) in treating people affected by melanoma, a relevant number of…”
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Prognostic tools for hypertrophic scar formation based on fundamental differences in systemic immunity by Bakker, Erik, Putten, Mirthe A. M., Heymans, Martijn W., Spiekstra, Sander W., Waaijman, Taco, Butzelaar, Liselotte, Negenborn, Vera L., Beekman, Vivian K., Akpinar, Erman O., Rustemeyer, Thomas, Niessen, Frank B., Gibbs, Susan

“…Unpredictable hypertrophic scarring (HS) occurs after approximately 35% of all surgical procedures and causes significant physical and psychological…”
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