Search Results - "Waaijer, C."

P16INK4a Positive Cells in Human Skin Are Indicative of Local Elastic Fiber Morphology, Facial Wrinkling, and Perceived Age by Waaijer, Mariëtte E C, Gunn, David A, Adams, Peter D, Pawlikowski, Jeff S, Griffiths, Christopher E M, van Heemst, Diana, Slagboom, P Eline, Westendorp, Rudi G J, Maier, Andrea B

“…Senescent cells are more prevalent in aged human skin compared to young, but evidence that senescent cells are linked to other biomarkers of aging is scarce…”
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MicroRNA-663 induction upon oxidative stress in cultured human fibroblasts depends on the chronological age of the donor by Waaijer, Mariëtte E. C., Wieser, Matthias, Grillari-Voglauer, Regina, van Heemst, Diana, Grillari, Johannes, Maier, Andrea B.

“…MicroRNAs, regulators of messenger RNA translation, have been observed to influence many physiological processes, amongst them the process of aging. Higher…”
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Are skin senescence and immunosenescence linked within individuals? by Waaijer, Mariëtte E. C., Goldeck, David, Gunn, David A., Heemst, Diana, Westendorp, Rudi G. J., Pawelec, Graham, Maier, Andrea B.

“…With advancing age, many organs exhibit functional deterioration. The age‐associated accumulation of senescent cells is believed to represent one factor…”
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Morphometric skin characteristics dependent on chronological and biological age: the Leiden Longevity Study by Waaijer, Mariette E. C., Gunn, David A., Catt, Sharon D., van Ginkel, Michael, de Craen, Anton J. M., Hudson, Nicole M., van Heemst, Diana, Slagboom, P. Eline, Westendorp, Rudi G. J., Maier, Andrea B.

“…The effect of chronological age on skin characteristics is readily visible, and its underlying histological changes have been a field of study for several…”
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Treatment effects and comorbid diseases in 58 patients with visual snow by van Dongen, Robin M, Waaijer, Lindy C, Onderwater, Gerrit L.J, Ferrari, Michel D, Terwindt, Gisela M

“…OBJECTIVETo evaluate pharmacologic treatment options for visual snow and to report prevalence of comorbid diseases. METHODSMedical charts of patients with a…”
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The number of p16INK4a positive cells in human skin reflects biological age by Waaijer, Mariëtte E.C., Parish, William E., Strongitharm, Barbara H., van Heemst, Diana, Slagboom, Pieternella E., de Craen, Anton J.M., Sedivy, John M., Westendorp, Rudi G.J., Gunn, David A., Maier, Andrea B.

“…Summary Cellular senescence is a defense mechanism in response to molecular damage which accumulates with aging. Correspondingly, the number of senescent cells…”
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Cellular senescence and chronological age in various human tissues: A systematic review and meta‐analysis by Tuttle, Camilla S. L., Waaijer, Mariette E. C., Slee‐Valentijn, Monique S., Stijnen, Theo, Westendorp, Rudi, Maier, Andrea B.

“…Senescent cells in tissues and organs are considered to be pivotal to not only the aging process but also the onset of chronic disease. Accumulating evidence…”
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Senescence in tissue samples of humans with age-related diseases: A systematic review by Tuttle, Camilla S.L., Luesken, Suzanne W.M., Waaijer, Mariette E.C., Maier, Andrea B.

“…•Higher numbers of senescent cells have been implicated in age-related diseases.•In humans, senescence is most studied in the heart and the respiratory…”
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The impact of geriatric characteristics and comorbidities on distant metastases and other cause mortality in older women with non-metastatic breast cancer treated with primary endocrine therapy by Waaijer, M. E.C., Lemij, A. A., de Boer, A. Z., Bastiaannet, E., van den Bos, F., Derks, M. G.M., Kroep, J. R., Liefers, G. J., Portielje, J. E.A., de Glas, N. A.

“…Introduction In recent years, primary surgical treatment of older women with non-metastatic breast cancer has decreased in favor of primary endocrine therapy…”
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Do senescence markers correlate in vitro and in situ within individual human donors? by Waaijer, Mariëtte E C, Gunn, David A, van Heemst, Diana, Slagboom, P Eline, Sedivy, John M, Dirks, Roeland W, Tanke, Hans J, Westendorp, Rudi G J, Maier, Andrea B

“…Little is known on how well senescence markers and correlate within individual donors. We studied correlations between the same and different markers…”
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Assessment of health status by molecular measures in adults ranging from middle-aged to old: Ready for clinical use? by Waaijer, M.E.C., Westendorp, R.G.J., Goldeck, D., Gunn, D.A., Pawelec, G., Stijntjes, M., Slagboom, P.E., Maier, A.B.

“…In addition to measures already used in clinical practice, molecular measures have been proposed to assess health status, but these have not yet been…”
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DNA damage markers in dermal fibroblasts in vitro reflect chronological donor age by Waaijer, Mariëtte E C, Croco, Eleonora, Westendorp, Rudi G J, Slagboom, P Eline, Sedivy, John M, Lorenzini, Antonello, Maier, Andrea B

“…The aging process is accompanied by an accumulation of cellular damage, which compromises the viability and function of cells and tissues. We aim to further…”
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First Look at the Physics Case of TLEP by Bicer, M, Yildiz, H. Duran, Coignet, G, Alexopoulos, T, Grojean, C, Sen, T, He, H. -J, Potamianos, K, Haug, S, Moreno, A, Heister, A, Sanz, V, Gomez-Ceballos, G, Klute, M, Dam, M, Glover, N, Krauss, F, Lenz, A, Syphers, M, Leonidopoulos, C, Sguazzoni, G, Antonelli, M, Boscolo, M, Dosselli, U, Frasciello, O, Milardi, C, Venanzoni, G, Zobov, M, van der Bij, J, de Gruttola, M, Kim, D. -W, Bachtis, M, Butterworth, A, Bernet, C, Botta, C, Carminati, F, David, A, d'Enterria, D, Deniau, L, Ganis, G, Goddard, B, Giudice, G, Janot, P, Jowett, J. M, Lourenco, C, Malgeri, L, Meschi, E, Moortgat, F, Perrozzi, L, Rinolfi, L, de Roeck, A, Rojo, J, Roy, G, Sciaba, A, Valassi, A, Wenninger, J, Woehri, H, Zimmermann, F, Koratzinos, M, Onel, Y, Bulyak, E, Porsuk, D, Kovalskyi, D, Ellis, J. R, Campanelli, M, Bai, Y, Chamizo, M, Appleby, R. B, Owen, H, Cuna, H. Maury, Gracios, C, Trentadue, L, Torrente-Lujan, E, Bertsche, D, Gramolin, A, Petroff, P, Azzi, P, Nicrosini, O, Piccinini, F, Montagna, G, Kapusta, F, Laplace, S, Gizani, N, Craig, N, Luci, C, Mele, B, Ciuchini, M, Aleksan, R, Lancon, E, Locci, E, Schwemling, P, Spiro, M, Moretti, S, Kikuchi, M, Koiso, H, Ohmi, K, Oide, K, Pauletta, G, de Austri, R. Ruiz, Gouzevitch, M

“…JHEP 01 (2014) 164 The discovery by the ATLAS and CMS experiments of a new boson with mass around 125 GeV and with measured properties compatible with those of…”
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The EUROnu Project by Edgecock, T. R, Fitton, M, Kelliher, D, Prior, C, Rogers, C, Thomason, J, Wildner, E, Efthymiopoulos, I, Gilardoni, S, Hansen, C, Martini, M, Osborne, J, Waaijer, C, Chancé, A, Payet, J, Baussan, E, Bobeth, C, Gaudiot, G, Lepers, B, Vassilopoulos, N, Wurtz, J, Zeter, V, Bielski, J, Kozien, M, Lacny, L, Ustrycka, A, Fourel, C, Giraud, J, Jacob, J, Lamy, T, Latrasse, L, Sortais, P, Thuillier, T, Mitrofanov, S, Loiselet, M, Keutgen, Th, Debray, F, Trophine, C, Daversin, C, Zorin, V, Izotov, I, Skalyga, V, Burt, G, Marchi, T, Cinausero, M, Gramegna, F, Prete, G, Collazuol, G, Mazzocco, M, Mezzetto, M, Signorini, C, Di Nitto, A, Brondi, A, Migliozzi, P, Hass, M, Schaumann, M, Stahl, A, Wehner, J, Bross, A, Neuffer, D, Wands, R, Soler, P, Agarwalla, S. K, Villanueva, A. Cervera, Mena, O, Agostino, L, Buizza-Avanzini, M, Patzak, T, Bogomilov, M, Matev, R, Tsenov, R, Lindner, M, Martinez, E. Fernández, García, M. C. González, Salvado, J, Coloma, P, López-Pavón, J, Orme, C, Pascoli, S, Tang, J, Ohlsson, T, Scotto-Lavina, L, Terranova, F, Bonesini, M, Alekou, A, Aslaninejad, M, Kurup, A, Jenner, L. J, Long, K, Pasternak, J, Back, J. J, Bogacz, A, Berg, J. S, Stratakis, D, Snopok, P, Bliss, N, Cordwell, M, Moss, A, Pattalwar, S, Apollonio, M

“…Phys. Rev. ST Accel. Beams 16 021002 (2013) The EUROnu project has studied three possible options for future, high intensity neutrino oscillation facilities in…”
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Sepsis and a swollen hand by Lorjé, T, Waaijer, M E C, Spierings, L E A M M

“…We describe a 53-year-old man presenting at the emergency department with sepsis and a swollen right hand. Over the course of a day a large haemorrhagic bulla…”
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