Search Results - "Waaga, A M"

Resistance to the mTOR-inhibitor RAD001 elevates integrin α2- and β1-triggered motility, migration and invasion of prostate cancer cells by Tsaur, I, Makarević, J, Juengel, E, Gasser, M, Waaga-Gasser, A-M, Kurosch, M, Reiter, M, Wedel, S, Bartsch, G, Haferkamp, A, Wiesner, C, Blaheta, R A

“…Background: Inhibitors of the mammalian target of rapamycin (mTOR) might become a novel tool to treat advanced prostate cancer. However, chronic drug exposure…”
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Effects of explosive brain death on cytokine activation of peripheral organs in the rat by TAKADA, M, NADEAU, K. C, HANCOCK, W. W, MACKENZIE, H. S, SHAW, G. D, WAAGA, A. M, CHANDRAKER, A, SAYEGH, M. H, TILNEY, N. L

“…The success rate of transplanted organs from brain-dead cadaver donors is consistently inferior to that of living sources. As cadaver and living unrelated…”
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Tumor cell dissemination in a human colon cancer animal model: orthotopic implantation or intraportal injection? by Thalheimer, A, Otto, C, Bueter, M, Illert, B, Gattenlohner, S, Gasser, M, Fein, M, Germer, C T, Waaga-Gasser, A-M

“…The development of therapeutic strategies for treatment of metastasized colorectal carcinoma requires biologically relevant and adequate animal models…”
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Mechanisms of chronic rejection by Waaga, Ana Maria, Gasser, Martin, Laskowski, Igor, Tilney, Nicholas L

“…Chronic rejection remains the major obstacle to long-term allograft survival. Detailed understanding of putative etiologic risk factors, both antigen-dependent…”
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Tumor Necrosis Factor-α is Associated with Positive Lymph Node Status in Patients with Recurrence of Colorectal Cancer – Indications for Anti-TNF-α Agents in Cancer Treatment by Grimm, M., Lazariotou, M., Kircher, S., Höfelmayr, A., Germer, C. T., von Rahden, B. H. A., Waaga-Gasser, A. M., Gasser, M.

“…Introduction : The progressive growth of malignancies is accompanied by a decline in the immune response through mechanisms which are poorly understood…”
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Inhibition of TLR4 signaling prolongs Treg-dependent murine islet allograft survival by Zhang, N, Krüger, B, Lal, G, Luan, Y, Yadav, A, Zang, W, Grimm, M, Waaga-Gasser, A.M, Murphy, B, Bromberg, J.S, Schröppel, B

“…Abstract Toll-like receptors (TLRs) provide an important link between innate and adaptive immune system. We hypothesized that the recognition of endogenous…”
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Modulation of the immune response with major histocompatability class II peptides via the indirect pathway of allorecognition after kidney and small bowel transplantation by Gasser, M, Lenhard, S.M, Otto, C, Kist-van Holthe, J.E, Navarro, E, Timmermann, W, Ulrichs, K, Thiede, A, Waaga, A.M

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Mechanisms of indirect allorecognition: Characterization of MHC class II allopeptide-specific T helper cell clones from animals undergoing acute allograft rejection by WAAGA, A. M, CHANDRAKER, A, SPADAFORA-FERREIRA, M, IYENGAR, A. R, KHOURY, S. J, CARPENTER, C. B, SAYEGH, M. H

“…Recent evidence indicates that T cells primed via the indirect pathway of allorecognition play an important role in allograft rejection, although the effector…”
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Mechanisms of indirect allorecognition in graft rejection : Class II MHC allopeptide-specific T cell clones transfer delayed-type hypersensitivity responses in vivo by CHEN, W, MURPHY, B, WAAGA, A. M, WILLETT, T. A, RUSSELL, M. E, KHOURY, S. J, SAYEGH, M. H

“…Recent animal studies suggest that indirect T-cell recognition of alloantigen plays an important role in allograft rejection and tolerance. In this study, we…”
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Oral immunoglobulin induces mononuclear cell apoptosis in patients suffering from idiopathic chronic pain syndrome: results from a pilot study by Waaga-Gasser, A M, Gasser, M, Stock, M, Grimm, M, Sprotte, G

“…The objective of this clinical pilot study was to examine the induction of apoptosis in mononuclear cells on treatment of patients with chronic pain syndrome…”
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Acceptance of small bowel allografts by indirect allorecognition of donor class II MHC allopeptides by Otto, C, Rohde, A.C, Timmermann, W, Waaga, A.M, Gebert, A, Gasser, M, Gassel, H.J, Thiede, A, Ulrichs, K

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Putative regulatory function of alloreactive Th2 cells in tolerant recipients after small bowel transplantation by Gasser, M, Otto, C, Timmermann, W, Waaga, A.M, Meyer, D, Gassel, H.J, Ulrichs, K, Thiede, A

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Class II MHC allopeptide-specific T-cell clones transfer delayed type hypersensitivity responses in vivo by Waaga, A.M., Murphy, B., Chen, W., Khoury, S.J., Sayegh, M.H.

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The role of CD154-CD40 versus CD28-B7 costimulatory pathways in regulating allogeneic Th1 and Th2 responses in vivo by Kishimoto, K, Dong, V M, Issazadeh, S, Fedoseyeva, E V, Waaga, A M, Yamada, A, Sho, M, Benichou, G, Auchincloss, Jr, H, Grusby, M J, Khoury, S J, Sayegh, M H

“…We used signal transducer and activator of transcription 4 (STAT4) and STAT6 gene knockout (-/-) mice as recipients of fully mismatched cardiac allografts to…”
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Regulatory functions of self-restricted MHC class II allopeptide-specific Th2 clones in vivo by Waaga, A M, Gasser, M, Kist-van Holthe, J E, Najafian, N, Müller, A, Vella, J P, Womer, K L, Chandraker, A, Khoury, S J, Sayegh, M H

“…We studied T-cell clones generated from grafts of rejecting and tolerant animals and investigated the regulatory function of Th2 clones in vitro and in vivo…”
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Activation patterns of specialized dendritic cells of the gut-associated lymphatic tissues following heterotopic small bowel transplantation in a graft-versus-host model of the rat by Fändrich, F, Waaga, A M, Schröder, J, Schweizer, E, Schmid, A, Jacob, S, Wacker, H H, Schroeder, P

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Impact of 15-deoxyspergualin on MHC class I and II antigen expression following small bowel transplantation in rats by Fändrich, F, Waaga, A M, Jacob, S, Schröder, J, Schweizer, E, Schroeder, P

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CD28-B7-Mediated T Cell Costimulation in Chronic Cardiac Allograft Rejection : Differential Role of B7-1 in Initiation versus Progression of Graft Arteriosclerosis by Kim, Kyung Soo, Denton, Mark D, Chandraker, Anil, Knoflach, Andreas, Milord, Rolando, Waaga, Anna Maria, Turka, Laurence A, Russell, Mary E, Peach, Robert, Sayegh, Mohamed H

“…Provision of adequate T cell costimulation is critical for the development of acute and chronic allograft rejection. We have previously reported that early…”
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Tumor necrosis factor-α is associated with positive lymph node status in patients with recurrence of colorectal cancer—indications for anti-TNF-α agents in cancer treatment by Grimm, M., Lazariotou, M., Kircher, S., Höfelmayr, A., Germer, C. T., von Rahden, B. H. A., Waaga-Gasser, A. M., Gasser, M.

“…Introduction The progressive growth of malignancies is accompanied by a decline in the immune response through mechanisms which are poorly understood…”
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Mechanisms of targeting CD28 by a signaling monoclonal antibody in acute and chronic allograft rejection by DONG, Victor M, XUELI YUAN, COITO, Ana J, WAAGA, Ana Maria, SAYEGH, Mohamed H, CHANDRAKER, Anil

“…There is increasing evidence that ongoing T-cell recognition of alloantigen and activation are key mediators of chronic allograft rejection. The CD28-B7…”
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