Search Results - "WUNDERLICH, GERHARD"
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Improved Plasmodium falciparum dilution cloning through efficient quantification of parasite numbers and c-SNARF detection
Published in Malaria journal (23-06-2021)“…Background Molecular and genetic studies of blood-stage Plasmodium falciparum parasites require limiting dilution cloning and prolonged cultivation in…”
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Editorial: From Apicomplexan Genes to Drug Discovery
Published in Frontiers in cellular and infection microbiology (10-11-2021)Get full text
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Association of the humoral immune response with the inflammatory profile in Plasmodium vivax infections in pregnant women
Published in PLoS neglected tropical diseases (01-11-2024)“…Plasmodium vivax infection, when it occurs during pregnancy, has often been associated with serious adverse pregnancy outcomes. However, immunological…”
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Adverse pregnancy outcomes are associated with Plasmodium vivax malaria in a prospective cohort of women from the Brazilian Amazon
Published in PLoS neglected tropical diseases (29-04-2021)“…Malaria in Brazil represents one of the highest percentages of Latin America cases, where approximately 84% of infections are attributed to Plasmodium (P.)…”
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A DNA Vaccine Encoding Plasmodium falciparum PfRH5 in Cationic Liposomes for Dermal Tattooing Immunization
Published in Vaccines (Basel) (20-10-2020)“…Vaccines are the primary means of controlling and preventing pandemics and outbreaks of pathogens such as bacteria, viruses, and parasites. However, a major…”
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The Transcription Factor PfAP2-O Influences Virulence Gene Transcription and Sexual Development in Plasmodium falciparum
Published in Frontiers in cellular and infection microbiology (28-06-2021)“…The human malaria parasite Plasmodium falciparum expresses variant PfEMP1 proteins on the infected erythrocyte, which function as ligands for endothelial…”
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Acquisition of antibodies to Plasmodium falciparum and Plasmodium vivax antigens in pregnant women living in a low malaria transmission area of Brazil
Published in Malaria journal (01-12-2022)“…Pregnant women have increased susceptibility to Plasmodium falciparum malaria and acquire protective antibodies over successive pregnancies. Most studies that…”
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Recombinant proteins of Plasmodium malariae merozoite surface protein 1 (PmMSP1): Testing immunogenicity in the BALB/c model and potential use as diagnostic tool
Published in PloS one (25-07-2019)“…Plasmodium malariae is the third most prevalent human malaria-causing species and has a patchy, but ample distribution in the world. Humans can host the…”
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TLR4-Mediated Placental Pathology and Pregnancy Outcome in Experimental Malaria
Published in Scientific reports (17-08-2017)“…Malaria-associate pregnancy has a significant impact on infant morbidity and mortality. The detrimental effects of malaria infection during pregnancy have been…”
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Establishment of an Antiplasmodial Vaccine Based on PfRH5-Encoding RNA Replicons Stabilized by Cationic Liposomes
Published in Pharmaceutics (01-04-2023)“…Nucleic acid-based vaccines have been studied for the past four decades, but the approval of the first messenger RNA (mRNA) vaccines during the COVID-19…”
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Production of glycosylphosphatidylinositol-anchored proteins for vaccines and directed binding of immunoliposomes to specific cell types
Published in The journal of venomous animals and toxins including tropical diseases (03-08-2020)“…Liposomes are highly useful carriers for delivering drugs or antigens. The association of glycosylphosphatidylinositol (GPI)-anchored proteins to liposomes…”
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Plasmodial Transcription Factors and Chromatin Modifiers as Drug Targets
Published in Future pharmacology (01-12-2023)“…The complex life cycle of the malaria parasite Plasmodium requires the parasite to adequately adapt to different conditions. For this reason, Plasmodium…”
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Systematic analysis of FKBP inducible degradation domain tagging strategies for the human malaria parasite Plasmodium falciparum
Published in PloS one (16-07-2012)“…Targeted regulation of protein levels is an important tool to gain insights into the role of proteins essential to cell function and development. In recent…”
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Knockdown of the Plasmodium falciparum SURFIN4.1 antigen leads to an increase of its cognate transcript
Published in PloS one (11-08-2017)“…The genome of the malaria parasite Plasmodium falciparum contains the surf gene family which encodes large transmembrane proteins of unknown function. While…”
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Violacein Extracted from Chromobacterium violaceum Inhibits Plasmodium Growth In Vitro and In Vivo
Published in Antimicrobial Agents and Chemotherapy (01-05-2009)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Antibody Profile Comparison against MSP1 Antigens of Multiple Plasmodium Species in Human Serum Samples from Two Different Brazilian Populations Using a Multiplex Serological Assay
Published in Pathogens (Basel) (04-09-2021)“…has a wide geographic distribution, but mainly at very low parasitemias and in co-infections, leading to an underestimated prevalence of this species. Studies…”
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Immunoproteomics of Plasmodium falciparum-infected red blood cell membrane fractions
Published in Memórias do Instituto Oswaldo Cruz (01-12-2017)“…The surface of infected red blood cells (iRBCs) has been widely investigated because of the molecular complexity and pathogenesis mechanisms involved…”
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DNA-Loaded Cationic Liposomes Efficiently Function as a Vaccine against Malarial Proteins
Published in Molecular therapy. Methods & clinical development (15-12-2017)“…The delivery of antigens as DNA vaccines is an efficient alternative to induce immune responses against antigens, which are difficult to produce in recombinant…”
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Carotenoid Biosynthesis in Intraerythrocytic Stages of Plasmodium falciparum
Published in The Journal of biological chemistry (10-04-2009)“…Carotenoids are widespread lipophilic pigments synthesized by all photosynthetic organisms and some nonphotosynthetic fungi and bacteria. All carotenoids are…”
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Dynamic activation and repression of the plasmodium falciparum rif gene family and their relation to chromatin modification
Published in PloS one (03-01-2012)“…The regulation of variant gene expression in Plasmodium falciparum is still only partially understood. Regulation of var genes, the most studied gene family…”
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