Search Results - "WUERZBERGER, S. M"

FBXO10 deficiency and BTK activation upregulate BCL2 expression in mantle cell lymphoma by Li, Y, Bouchlaka, M N, Wolff, J, Grindle, K M, Lu, L, Qian, S, Zhong, X, Pflum, N, Jobin, P, Kahl, B S, Eickhoff, J C, Wuerzberger-Davis, S M, Miyamoto, S, Thomas, C J, Yang, D T, Capitini, C M, Rui, L

“…Targeting Bruton tyrosine kinase (BTK) by ibrutinib is an effective treatment for patients with relapsed/refractory mantle cell lymphoma (MCL). However, both…”
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NF-κB activation by combinations of NEMO SUMOylation and ATM activation stresses in the absence of DNA damage by WUERZBERGER -DAVIS, S. M, NAKAMURA, Y, SEUFZER, B. J, MIYAMOTO, S

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Induction of apoptosis in MCF-7:WS8 breast cancer cells by β-lapachone by WUERZBERGER, S. M, PINK, J. J, PLANCHON, S. M, BYERS, K. L, BORNMANN, W. G, BOOTHMAN, D. A

“…Beta-lapachone (beta-lap) affects a number of enzymes in vitro, including type I topoisomerase (Topo I); however, its exact intracellular target(s) and…”
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Bcl-2 protects against beta-lapachone-mediated caspase 3 activation and apoptosis in human myeloid leukemia (HL-60) cells by Planchon, S M, Wuerzberger-Davis, S M, Pink, J J, Robertson, K A, Bornmann, W G, Boothman, D A

“…We previously demonstrated that beta-lapachone (beta-lap) killed cancer cells solely by apoptosis. Beta-Lap induced apoptosis in HL-60 cells in a…”
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NF- Kappa B Activation by Camptothecin. A LINKAGE BETWEEN NUCLEAR DNA DAMAGE AND CYTOPLASMIC SIGNALING EVENTS by Huang, T T, Wuerzberger-Davis, S M, Seufzer, B J, Shumway, S D, Kurama, T, Boothman, DA, Miyamoto, S

“…Activation of the transcription factor NF- Kappa B by extracellular signals involves its release from the inhibitor protein I Kappa B alpha in the cytoplasm…”
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Coordinate modulation of Sp1, NF‐kappa B, and p53 in confluent human malignant melanoma cells after ionizing radiation by Yang, Chin-Rang, Wilson-Van Patten, Carmell, Planchon, Sarah M., Wuerzberger-Davis, Shelly M., Davis, Thomas W., Cuthill, Scott, Miyamoto, Shigeki, Boothman, David A.

“…ABSTRACT Regulation of transcriptional responses in growth‐arrested human cells under conditions that promote potentially lethal damage repair after ionizing…”
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Damage‐Sensing mechanisms in human cells after ionizing radiation by Boothman, David A, Burrows, Heather L, Yang, Chin‐Rang, Davis, Thomas D, Wuerzberger, Shelly M, Planchon, Sarah M, Odegaard, Eric, Lewis, Janet E, Pink, John, Meyers, Mark, Van Patten, Carmell Wilson, Sharda, Navneet, Kinsella, Timothy J

“…Human cells have evolved several mechanisms for responding to damage created by ionizing radiation. Some of these responses involve the activation or…”
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Sequential Modification of NEMO/IKKγ by SUMO-1 and Ubiquitin Mediates NF-κB Activation by Genotoxic Stress by Huang, Tony T, Wuerzberger-Davis, Shelly M, Wu, Zhao-Hui, Miyamoto, Shigeki

“…The transcription factor NF-κB is critical for setting the cellular sensitivities to apoptotic stimuli, including DNA damaging anticancer agents. Central to…”
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Nuclear Export of the NF-κB Inhibitor IκBα Is Required for Proper B Cell and Secondary Lymphoid Tissue Formation by Wuerzberger-Davis, Shelly M., Chen, Yuhong, Yang, David T., Kearns, Jeffrey D., Bates, Paul W., Lynch, Candace, Ladell, Nicholas C., Yu, Mei, Podd, Andrew, Zeng, Hu, Huang, Tony T., Wen, Renren, Hoffmann, Alexander, Wang, Demin, Miyamoto, Shigeki

“…The N-terminal nuclear export sequence (NES) of inhibitor of nuclear factor kappa B (NF-κB) alpha (IκBα) promotes NF-κB export from the cell nucleus to the…”
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NF- B activation by combinations of NEMO SUMOylation and ATM activation stresses in the absence of DNA damage by Wuerzberger-Davis, S M, Nakamura, Y, Seufzer, B J, Miyamoto, S

“…The inactive transcription factor NF-kappaB is localized in the cytoplasm and rapidly responds to a variety of extracellular factors and intracellular stress…”
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NF-kappaB activation by combinations of NEMO SUMOylation and ATM activation stresses in the absence of DNA damage by Wuerzberger-Davis, S M, Nakamura, Y, Seufzer, B J, Miyamoto, S

“…The inactive transcription factor NF-kappaB is localized in the cytoplasm and rapidly responds to a variety of extracellular factors and intracellular stress…”
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NF-[kappa]B activation by combinations of NEMO SUMOylation and ATM activation stresses in the absence of DNA damage by Wuerzberger-Davis, S M, Nakamura, Y, Seufzer, B J, Miyamoto, S

“…The inactive transcription factor NF-[kappa]B is localized in the cytoplasm and rapidly responds to a variety of extracellular factors and intracellular stress…”
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μ-Calpain Activation in β-Lapachone-Mediated Apoptosis by Tagliarino, Colleen, Pink, John J., Reinicke, Kathryn, Simmers, Sara M., Boothman, David A.

“…β-Lapachone (β-Lap) triggers apoptosis in a number of human breast and prostate cancer cell lines through a unique apoptotic pathway that is dependent upon…”
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NF-kappaB activation by camptothecin. A linkage between nuclear DNA damage and cytoplasmic signaling events by Huang, T T, Wuerzberger-Davis, S M, Seufzer, B J, Shumway, S D, Kurama, T, Boothman, D A, Miyamoto, S

“…Activation of the transcription factor NF-kappaB by extracellular signals involves its release from the inhibitor protein IkappaBalpha in the cytoplasm and…”
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