Search Results - "WU, Kendall"
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Suppression of Mammary Tumorigenesis in Transgenic Mice by the RXR-selective Retinoid, LGD1069
Published in Cancer epidemiology, biomarkers & prevention (01-05-2002)“…Retinoids have been used in the clinic for the prevention and treatment of human cancers. They regulate several cellular processes including growth,…”
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An elt-3/elt-5/elt-6 GATA Transcription Circuit Guides Aging in C. elegans
Published in Cell (25-07-2008)“…To define the C. elegans aging process at the molecular level, we used DNA microarray experiments to identify a set of 1294 age-regulated genes and found that…”
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9-cis-Retinoic Acid Suppresses Mammary Tumorigenesis in C3(1)-Simian Virus 40 T Antigen-transgenic Mice
Published in Clinical cancer research (01-09-2000)“…Retinoids have been investigated as potential agents for the prevention and treatment of human cancers. These compounds play an important role in regulating…”
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The retinoid X receptor-selective retinoid, LGD1069, prevents the development of estrogen receptor-negative mammary tumors in transgenic mice
Published in Cancer research (Chicago, Ill.) (15-11-2002)“…Despite the effectiveness of the selective estrogen receptor (ER) modulators in preventing ER-positive breast cancer, chemopreventive agents still need to be…”
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Estrogen receptor DNA binding is not required for estrogen-induced breast cell growth
Published in Molecular and cellular endocrinology (15-10-2007)“…In this study, we determined whether ER DNA binding is necessary for estrogen to stimulate the growth of breast cancer cells. To investigate the requirement of…”
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The retinoid X receptor-selective retinoid, LGD1069, down- regulates cyclooxygenase-2 expression in human breast cells through transcription factor crosstalk : Implications for molecular-based chemoprevention
Published in Cancer research (Chicago, Ill.) (15-04-2005)“…Retinoids and their derivatives can suppress the development of cancer in animals and in humans. We and others have shown that retinoid X receptor…”
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Receptor-selective retinoids inhibit the growth of normal and malignant breast cells by inducing G1 cell cycle blockade
Published in Breast cancer research and treatment (01-03-2006)“…Despite advances in treatment, breast cancer continues to be the second leading cause of cancer mortality in women. Statistics suggest that while focus on…”
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Is Low-Dose Tamoxifen Useful for the Treatment and Prevention of Breast Cancer?
Published in JNCI : Journal of the National Cancer Institute (04-06-2003)Get full text
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Role of retinoid receptors in the prevention and treatment of breast cancer
Published in Journal of mammary gland biology and neoplasia (01-10-1999)“…Retinoids are vitamin A-related compounds that have been found to prevent cancer in animals and humans. In this review, we discuss the role of retinoids and…”
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