Search Results - "WU, A. H. B"

Tamoxifen Metabolite Concentrations, CYP2D6 Genotype, and Breast Cancer Outcomes by Madlensky, L, Natarajan, L, Tchu, S, Pu, M, Mortimer, J, Flatt, SW, Nikoloff, DM, Hillman, G, Fontecha, MR, Lawrence, HJ, Parker, BA, Wu, AHB, Pierce, JP

“…We explored whether breast cancer outcomes are associated with endoxifen and other metabolites of tamoxifen and examined potential correlates of endoxifen…”
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Multicenter Evaluation of the Cepheid Xpert Hepatitis C Virus Viral Load Assay by McHugh, M P, Wu, A H B, Chevaliez, S, Pawlotsky, J M, Hallin, M, Templeton, K E

“…Viral load monitoring for hepatitis C virus (HCV) is necessary to diagnose infection and monitor response to therapy, but the tests involved are currently…”
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An Antiestrogenic Activity Score for tamoxifen and its metabolites is associated with breast cancer outcome by de Vries Schultink, A. H. M., Alexi, X., van Werkhoven, E., Madlensky, L., Natarajan, L., Flatt, S. W., Zwart, W., Linn, S. C., Parker, B. A., Wu, A. H. B., Pierce, J. P., Huitema, A. D. R., Beijnen, J. H.

“…Purpose Endoxifen concentrations have been associated with breast cancer recurrence in tamoxifen-treated patients. However, tamoxifen itself and other…”
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Evaluation of Tamoxifen and Metabolites by LC-MS/MS and HPLC Methods by Heath, D.D., Flatt, S.W., Wu, A. H. B., Pruitt, M. A., Rock, C. L.

“…Epidemiological and laboratory evidence suggests that quantification of serum or plasma levels of tamoxifen and its metabolites,…”
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Effect of Single-Dose Rifampin on the Pharmacokinetics of Warfarin in Healthy Volunteers by Frymoyer, A, Shugarts, S, Browne, M, Wu, A H B, Frassetto, L, Benet, L Z

“…Based on in vitro rat and human hepatocyte uptake studies showing inhibition of warfarin uptake in the presence of the nonspecific organic anion–transporting…”
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Limitations of Point-of-Care Testing in the ED or ICU: A Role for Regional Centralized Toxicology Laboratories by Wu, A H B

“…Although speed in reporting results of clinical laboratory testing for emergency department and intensive care unit patients is always desirable, for clinical…”
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Comparison of Information-Dependent Acquisition on a Tandem Quadrupole TOF vs a Triple Quadrupole Linear Ion Trap Mass Spectrometer for Broad-Spectrum Drug Screening by Thoren, Katie L, Colby, Jennifer M, Shugarts, Sarah B, Wu, Alan H B, Lynch, Kara L

“…Liquid chromatography high-resolution mass spectrometry (LC-HRMS) with untargeted data collection is especially attractive for general unknown drug screening…”
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Performance characteristics of a high-sensitivity cardiac troponin assay using plasma and whole blood samples by Li, P., Enea, N.S., Zuk, R., Tan, H., Wu, A.H.B., Jaffe, A.S.

“…•Using AACC Universal Sample Bank, Pylon assay shown to be second-generation hs-cTn.•>90% of whole blood samples of 505 healthy donors were measurable.•Good…”
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Multi-site Clinical Evaluation of the Xpert® HIV-1 Viral Load Assay by Jordan, J.A, Plantier, J.C, Templeton, K, Wu, A.H.B

“…Highlights • HIV-1 RNA was quantified over the range of 40 to 107 copies/mL. • HIV-1 Group M subtypes A-D, F-H, J, K, CRFs AB, AE, AG, and Groups N & O…”
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Association of CYP2C92 With Bosentan-Induced Liver Injury by Markova, S M, De Marco, T, Bendjilali, N, Kobashigawa, E A, Mefford, J, Sodhi, J, Le, H, Zhang, C, Halladay, J, Rettie, A E, Khojasteh, C, McGlothlin, D, Wu, A H B, Hsueh, W-C, Witte, J S, Schwartz, J B, Kroetz, D L

“…Bosentan (Tracleer) is an endothelin receptor antagonist prescribed for the treatment of pulmonary arterial hypertension (PAH). Its use is limited by…”
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Cross-reactivity studies and predictive modeling of "Bath Salts" and other amphetamine-type stimulants with amphetamine screening immunoassays by Petrie, M., Lynch, K. L., Ekins, S., Chang, J. S., Goetz, R. J., Wu, A. H. B., Krasowski, M. D.

“…Introduction. The increasing abuse of amphetamine-like compounds presents a challenge for clinicians and clinical laboratories. Although these compounds may be…”
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Rapid screening for the detection of HLA-B57 and HLA-B58 in prevention of drug hypersensitivity by Kostenko, L., Kjer-Nielsen, L., Nicholson, I., Hudson, F., Lucas, A., Foley, B., Chen, K., Lynch, K., Nguyen, J., Wu, A. H. B., Tait, B. D., Holdsworth, R., Mallal, S., Rossjohn, J., Bharadwaj, M., McCluskey, J.

“…HLA‐B57 and HLA‐B58 are major histocompatibility class (MHC)‐I allotypes that are potentially predictive of important clinical immune phenotypes. HLA‐B*5701 is…”
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Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data by Klein, T E, Altman, R B, Eriksson, N, Gage, B F, Kimmel, S E, Lee, M-T M, Limdi, N A, Page, D, Roden, D M, Wagner, M J, Caldwell, M D, Johnson, J A

“…There is substantial variation in the dose of warfarin required to achieve therapeutic anticoagulation. In this study, mathematical models for warfarin dosage…”
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Prevalence of Smoking Assessed Biochemically in an Urban Public Hospital: A Rationale for Routine Cotinine Screening by Benowitz, Neal L., Schultz, Katherine E., Haller, Christine A., Wu, Alan H. B., Dains, Katherine M., Jacob, Peyton

“…Cotinine, a metabolite of nicotine, has been used to study tobacco smoke exposure in population studies, but the authors are unaware of its use to screen…”
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The Analysis of Thebaine in Urine for the Detection of Poppy Seed Consumption by Cassella, Gina, Wu, Alan H.B., Shaw, Brenda R., Hill, Dennis W.

“…The consumption of poppy seeds in various foods may lead to a positive opiate result in urine subjected to testing for drugs of abuse. As a natural constituent…”
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Analysis of Codeine Positivity in Urine of Pain Management Patients by Colby, Jennifer M., Wu, Alan H.B., Lynch, Kara L.

“…The opioids codeine and morphine have legitimate uses in managing chronic pain conditions, but they are frequently abused. Patients prescribed opioids submit…”
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Lack of  -Hydroxybutyrate Prevalence Among An Urban Emergency Department Population by Ureda, N., Ruan, W., French, D., Wu, A. H. B.

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Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data

“…Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data Original Article, N Engl J Med 2009:360;753-764.. In Table 2 (page 758), the mean…”
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Incomplete Recovery of Prescription Opioids in Urine using Enzymatic Hydrolysis of Glucuronide Metabolites by Wang, Ping, Stone, Judith A., Chen, Katherine H., Gross, Susan F., Haller, Christine A., Wu, Alan H.B.

“…Confirmation of opioids in urine samples of clinical patients requires liberation of opioids from their glucuronide conjugates. Both acid hydrolysis and enzyme…”
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Evaluation of the triage system for emergency drugs-of-abuse testing in urine by Wu, A H, Wong, S S, Johnson, K G, Callies, J, Shu, D X, Dunn, W E, Wong, S H

“…The Triage Panel for Drugs of Abuse (DOA) was evaluated for detection of phencyclidine (PCP), amphetamines (AMPH), opiates (OPI), tetrahydrocannabinol (THC),…”
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