Search Results - "WRIGHT, Elizabeth C"

Protection from Obesity and Diabetes by Blockade of TGF-β/Smad3 Signaling by Yadav, Hariom, Quijano, Celia, Kamaraju, Anil K., Gavrilova, Oksana, Malek, Rana, Chen, Weiping, Zerfas, Patricia, Zhigang, Duan, Wright, Elizabeth C., Stuelten, Christina, Sun, Peter, Lonning, Scott, Skarulis, Monica, Sumner, Anne E., Finkel, Toren, Rane, Sushil G.

“…Imbalances in glucose and energy homeostasis are at the core of the worldwide epidemic of obesity and diabetes. Here, we illustrate an important role of the…”
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Erythropoietin treatment and the risk of hip fractures in hemodialysis patients by Suresh, Sukanya, Wright, Elizabeth C., Wright, Daniel G., Abbott, Kevin C., Noguchi, Constance T.

“…ABSTRACT Erythropoietin (EPO) is the primary regulator of bone marrow erythropoiesis. Mouse models have provided evidence that EPO also promotes bone…”
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Microglia as Dynamic Cellular Mediators of Brain Function by Wright-Jin, Elizabeth C., Gutmann, David H.

“…Originally hypothesized to function solely as immunologic responders within the central nervous system (CNS), emerging evidence has revealed that microglia…”
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High nitrate levels in skeletal muscle contribute to nitric oxide generation via a nitrate/nitrite reductive pathway in mice that lack the nNOS enzyme by Upanan, Supranee, Lee, Jeeyoung, Tunau-Spencer, Khalid J, Rajvanshi, Praveen K, Wright, Elizabeth C, Noguchi, Constance T, Schechter, Alan N

“…Nitric oxide (NO) is a vasodilator gas that plays a critical role in mitochondrial respiration and skeletal muscle function. NO is endogenously generated by NO…”
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Prognostic value of Ishak fibrosis stage: Findings from the hepatitis C antiviral long‐term treatment against cirrhosis trial by Everhart, James E., Wright, Elizabeth C., Goodman, Zachary D., Dienstag, Jules L., Hoefs, John C., Kleiner, David E., Ghany, Marc G., Mills, A. Scott, Nash, S. Russell, Govindarajan, Sugantha, Rogers, Thomas E., Greenson, Joel K., Brunt, Elizabeth M., Bonkovsky, Herbert L., Morishima, Chihiro, Litman, Heather J.

“…Studies of the prognostic value of Ishak fibrosis stage are lacking. We used multi‐year follow‐up of the Hepatitis C Antiviral Long‐Term Treatment Against…”
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Time to Publication for Randomized Clinical Trials Presented as Abstracts at Three Gastroenterology and Hepatology Conferences in 2017 by Wright, Elizabeth C., Kapuria, Devika, Ben-Yakov, Gil, Sharma, Disha, Basu, Dev, Cho, Min Ho, Abijo, Tomilowo, Wilkins, Kenneth J.

“…Results of randomized clinical trials are often first presented as conference abstracts but these abstracts may be difficult to find, and trial results…”
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Influence of Day Length and Physical Activity on Sleep Patterns in Older Icelandic Men and Women by Brychta, Robert J, Arnardottir, Nanna Yr, Johannsson, Erlingur, Wright, Elizabeth C, Eiriksdottir, Gudny, Gudnason, Vilmundur, Marinac, Catherine R, Davis, Megan, Koster, Annemarie, Caserotti, Paolo, Sveinsson, Thorarinn, Harris, Tamara, Chen, Kong Y

“…To identify cross-sectional and seasonal patterns of sleep and physical activity (PA) in community-dwelling, older Icelandic adults using accelerometers. A…”
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Differential regional and subtype-specific vulnerability of enteric neurons to mitochondrial dysfunction by Viader, Andreu, Wright-Jin, Elizabeth C, Vohra, Bhupinder P S, Heuckeroth, Robert O, Milbrandt, Jeffrey

“…Mitochondrial dysfunction is a central mediator of disease progression in diverse neurodegenerative diseases that often present with prominent gastrointestinal…”
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Increased reticulocytosis during infancy is associated with increased hospitalizations in sickle cell anemia patients during the first three years of life by Meier, Emily Riehm, Byrnes, Colleen, Lee, Y Terry, Wright, Elizabeth C, Schechter, Alan N, Luban, Naomi L C, Miller, Jeffery L

“…Among older children with sickle cell anemia, leukocyte counts, hemoglobin, and reticulocytosis have previously been suggested as disease severity markers…”
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Neurofibromatosis 1 - Mutant microglia exhibit sexually-dimorphic cyclic AMP-dependent purinergic defects by Elmadany, Nirmeen, Logiacco, Francesca, Buonfiglioli, Alice, Haage, Verena C., Wright-Jin, Elizabeth C., Schattenberg, Alexander, Papawassiliou, Roxane M., Kettenmann, Helmut, Semtner, Marcus, Gutmann, David H.

“…As critical regulators of brain homeostasis, microglia are influenced by numerous factors, including sex and genetic mutations. To study the impact of these…”
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Fibrosis progression in chronic hepatitis C: Morphometric image analysis in the HALT‐C trial by Goodman, Zachary D., Stoddard, Anne M., Bonkovsky, Herbert L., Fontana, Robert J., Ghany, Marc G., Morgan, Timothy R., Wright, Elizabeth C., Brunt, Elizabeth M., Kleiner, David E., Shiffman, Mitchell L., Everson, Gregory T., Lindsay, Karen L., Dienstag, Jules L., Morishima, Chihiro

“…Computer‐assisted morphometry can provide precise measurement of hepatic fibrosis on a continuous scale. Previous morphometric studies of large cohorts of…”
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Variants in interferon‐alpha pathway genes and response to pegylated interferon‐Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long‐term treatment against cirrhosis trial by Welzel, Tania Mara, Morgan, Timothy R., Bonkovsky, Herbert L., Naishadham, Deepa, Pfeiffer, Ruth M., Wright, Elizabeth C., Hutchinson, Amy A., Crenshaw, Andrew T., Bashirova, Arman, Carrington, Mary, Dotrang, Myhanh, Sterling, Richard K., Lindsay, Karen L., Fontana, Robert J., Lee, William M., Di Bisceglie, Adrian M., Ghany, Marc G., Gretch, David R., Chanock, Stephen J., Chung, Raymond T., O'Brien, Thomas R.

“…Combination treatment with pegylated‐interferon‐alpha (PEG IFN‐α) and ribavirin, the current recommended therapy for chronic hepatitis C virus (HCV) infection,…”
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Abnormal liver tests are not sufficient for diagnosis of hepatic graft‐versus‐host disease in critically ill patients by Yang, Alexander H., Han, Mai Ai Thanda, Samala, Niharika, Rizvi, Bisharah S., Marchalik, Rachel, Etzion, Ohad, Wright, Elizabeth C., Patel, Ruchi, Khan, Vinshi, Kapuria, Devika, Samala Venkat, Vikramaditya, Kleiner, David E., Koh, Christopher, Kanakry, Jennifer A., Kanakry, Christopher G., Pavletic, Steven, Williams, Kirsten M., Heller, Theo

“…Hepatic graft‐versus‐host disease (HGVHD) contributes significantly to morbidity and mortality after hematopoietic stem cell transplantation (HSCT). Clinical…”
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Prevalence of Estimated GFR Reporting Among US Clinical Laboratories by Accetta, Nancy A., MHS, CHES, Gladstone, Elisa H., MPH, DiSogra, Charles, DrPH, MPH, Wright, Elizabeth C., PhD, Briggs, Michael, Narva, Andrew S., MD

“…Background Routine laboratory reporting of estimated glomerular filtration rate (eGFR) may help clinicians detect kidney disease. The current national…”
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Effect of HCV RNA Suppression During Peginterferon Alfa-2a Maintenance Therapy on Clinical Outcomes in the HALT-C Trial by Shiffman, Mitchell L, Morishima, Chihiro, Dienstag, Jules L, Lindsay, Karen L, Hoefs, John C, Lee, William M, Wright, Elizabeth C, Naishadham, Deepa, Everson, Gregory T, Lok, Anna S, Di Bisceglie, Adrian M, Bonkovsky, Herbert L, Ghany, Marc G

“…Background & Aims The Hepatitis C Antiviral Long-term Treatment Against Cirrhosis (HALT-C) trial demonstrated that low-dose peginterferon maintenance therapy…”
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Safety and efficacy of pegylated interferon α-2a and ribavirin for the treatment of hepatitis C in patients with thalassemia by HARMATZ, Paul, JONAS, Maureen M, KWIATKOWSKI, Janet L, WRIGHT, Elizabeth C, FISCHER, Roland, VICHINSKY, Elliott, GIARDINA, Patricia J, NEUFELD, Ellis J, PORTER, John, OLIVIERI, Nancy

“…Antiviral treatment of hepatitis C virus in thalassemia has raised concerns of ribavirin-induced hemolysis and increased iron loading. This study examined the…”
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Inactivation of Microbial Arginine Deiminases by l-Canavanine by Li, Ling, Li, Zhimin, Chen, Danqi, Lu, Xuefeng, Feng, Xiaohua, Wright, Elizabeth C, Solberg, Nathan O, Dunaway-Mariano, Debra, Mariano, Patrick S, Galkin, Andrey, Kulakova, Liudmila, Herzberg, Osnat, Green-Church, Kari B, Zhang, Liwen

“…Arginine deiminase (ADI) catalyzes the hydrolytic conversion of l-arginine to ammonia and l-citrulline as part of the energy-producing l-arginine degradation…”
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A Novel Non-Invasive Murine Model of Neonatal Hypoxic-Ischemic Encephalopathy Demonstrates Developmental Delay and Motor Deficits with Activation of Inflammatory Pathways in Monocytes by Lemanski, Elise A, Collins, Bailey A, Ebenezer, Andrew T, Anilkumar, Sudha, Langdon, Victoria A, Zheng, Qi, Ding, Shanshan, Franke, Karl Royden, Schwarz, Jaclyn M, Wright-Jin, Elizabeth C

“…Neonatal hypoxic-ischemic encephalopathy (HIE) occurs in 1.5 per 1000 live births, leaving affected children with long-term motor and cognitive deficits. Few…”
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Association of γ‐glutamyl transferase (GGT) activity with treatment and clinical outcomes in chronic hepatitis C (HCV) by Everhart, James E., Wright, Elizabeth C.

“…Increased γ‐glutamyl transferase (GGT) activity is associated with liver injury and with mortality in the general population. Less is known about its…”
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The relationship of acute transfusion-associated hepatitis to the development of cirrhosis in the presence of alcohol abuse by HARRIS, D. Robert, GONIN, Rend, ALTER, Harvey J, WRIGHT, Elizabeth C, BUSKELL, Zelma J, HOLLINGER, F. Blaine, SEEFF, Leonard B

“…Although concomitant alcoholism is widely believed to enhance liver disease progression in persons with hepatitis C virus (HCV) infection, this relationship…”
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