Search Results - "WREN, Brendan"

Flagellin O -linked glycans are required for the interactions between Campylobacter jejuni and Acanthamoebae castellanii by Nasher, Fauzy, Wren, Brendan W

“…The predation and engulfment of bacteria by facilitates intimate interactions between host and prey. This process plays an important and underestimated role in…”
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'Add, stir and reduce': Yersinia spp. as model bacteria for pathogen evolution by McNally, Alan, Thomson, Nicholas R., Reuter, Sandra, Wren, Brendan W.

“…Key Points The evolution of mammalian pathogenesis in the Yersinia genus has occurred in different lineages in parallel through a balanced mixture of gene gain…”
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Transient internalization of Campylobacter jejuni in Amoebae enhances subsequent invasion of human cells by Nasher, Fauzy, Wren, Brendan W

“…The ubiquitous unicellular eukaryote, , is known to play a role in the survival and dissemination of is the leading cause of bacterial foodborne…”
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Microbe Profile: Campylobacter jejuni - survival instincts by Gundogdu, Ozan, Wren, Brendan W

“…is considered to be the most common bacterial cause of human gastroenteritis worldwide. can cause bloody diarrhoea, fever and abdominal pain in humans along…”
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Bacterial epidemiology and biology - lessons from genome sequencing by Parkhill, Julian, Wren, Brendan W

“…Next-generation sequencing has ushered in a new era of microbial genomics, enabling the detailed historical and geographical tracing of bacteria. This is…”
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Para-cresol production by Clostridium difficile affects microbial diversity and membrane integrity of Gram-negative bacteria by Passmore, Ian J, Letertre, Marine P M, Preston, Mark D, Bianconi, Irene, Harrison, Mark A, Nasher, Fauzy, Kaur, Harparkash, Hong, Huynh A, Baines, Simon D, Cutting, Simon M, Swann, Jonathan R, Wren, Brendan W, Dawson, Lisa F

“…Clostridium difficile is a Gram-positive spore-forming anaerobe and a major cause of antibiotic-associated diarrhoea. Disruption of the commensal microbiota,…”
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Unravelling mechanisms of bacterial recognition by Acanthamoeba: insights into microbial ecology and immune responses by Nasher, Fauzy, Wren, Brendan W

“…Acanthamoeba, are ubiquitous eukaryotic microorganisms, that play a pivotal role in recognizing and engulfing various microbes during predation, offering…”
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Recent advances in the production of recombinant glycoconjugate vaccines by Kay, Emily, Cuccui, Jon, Wren, Brendan W.

“…Glycoconjugate vaccines against bacteria are one of the success stories of modern medicine and have led to a significant reduction in the global occurrence of…”
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The importance of the glycosylation of antimicrobial peptides: natural and synthetic approaches by Bednarska, Natalia G., Wren, Brendan W., Willcocks, Sam J.

“…Glycosylation is one of the most prevalent post-translational modifications of a protein, with a defining impact on its structure and function. Many of the…”
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Characterisation of Clostridium difficile biofilm formation, a role for Spo0A by Dawson, Lisa F, Valiente, Esmeralda, Faulds-Pain, Alexandra, Donahue, Elizabeth H, Wren, Brendan W

“…Clostridium difficile is a Gram-positive anaerobic, spore-forming bacillus that is the leading cause of nosocomial diarrhoea worldwide. We demonstrate that C…”
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Bacterial pathogenomics by Pallen, Mark J, Wren, Brendan W

“…Genomes from all of the crucial bacterial pathogens of humans, plants and animals have now been sequenced, as have genomes from many of the important…”
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The Clostridium difficile spo0A Gene Is a Persistence and Transmission Factor by DEAKIN, Laura J, CLARE, Simon, FAGAN, Robert P, DAWSON, Lisa F, PICKARD, Derek J, WEST, Michael R, WREN, Brendan W, FAIRWEATHER, Neil F, DOUGAN, Gordon, LAWLEY, Trevor D

“…OA  Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Campylobacter jejuni Modulates Reactive Oxygen Species Production and NADPH Oxidase 1 Expression in Human Intestinal Epithelial Cells by Hong, Geunhye, Davies, Cadi, Omole, Zahra, Liaw, Janie, Grabowska, Anna D., Canonico, Barbara, Corcionivoschi, Nicolae, Wren, Brendan W., Dorrell, Nick, Elmi, Abdi, Gundogdu, Ozan

“…Campylobacter jejuni is the major bacterial cause of foodborne gastroenteritis worldwide. Mechanistically, how this pathogen interacts with intrinsic defence…”
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Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium by Stabler, Richard A, He, Miao, Dawson, Lisa, Martin, Melissa, Valiente, Esmeralda, Corton, Craig, Lawley, Trevor D, Sebaihia, Mohammed, Quail, Michael A, Rose, Graham, Gerding, Dale N, Gibert, Maryse, Popoff, Michel R, Parkhill, Julian, Dougan, Gordon, Wren, Brendan W

“…The continued rise of Clostridium difficile infections worldwide has been accompanied by the rapid emergence of a highly virulent clone designated PCR-ribotype…”
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Emergence and global spread of epidemic healthcare-associated Clostridium difficile by He, Miao, Miyajima, Fabio, Roberts, Paul, Ellison, Louise, Pickard, Derek J, Martin, Melissa J, Connor, Thomas R, Harris, Simon R, Fairley, Derek, Bamford, Kathleen B, D'Arc, Stephanie, Brazier, Jon, Brown, Derek, Coia, John E, Douce, Gill, Gerding, Dale, Kim, Hee Jung, Koh, Tse Hsien, Kato, Haru, Senoh, Mitsutoshi, Louie, Tom, Michell, Stephen, Butt, Emma, Peacock, Sharon J, Brown, Nick M, Riley, Tom, Songer, Glen, Wilcox, Mark, Pirmohamed, Munir, Kuijper, Ed, Hawkey, Peter, Wren, Brendan W, Dougan, Gordon, Parkhill, Julian, Lawley, Trevor D

“…Trevor Lawley and colleagues report whole-genome sequencing of a large global collection of Clostridium difficile , the most common cause of…”
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Protein glycosylation in bacterial mucosal pathogens by Szymanski, Christine M, Wren, Brendan W

“…In eukaryotes, glycosylated proteins are ubiquitous components of extracellular matrices and cellular surfaces. Their oligosaccharide moieties are implicated…”
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Transcriptional analysis of temporal gene expression in germinating Clostridium difficile 630 endospores by Dembek, Marcin, Stabler, Richard A, Witney, Adam A, Wren, Brendan W, Fairweather, Neil F

“…Clostridium difficile is the leading cause of hospital acquired diarrhoea in industrialised countries. Under conditions that are not favourable for growth, the…”
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Characterization of Posttranslationally Modified Multidrug Efflux Pumps Reveals an Unexpected Link between Glycosylation and Antimicrobial Resistance by Abouelhadid, Sherif, Raynes, John, Bui, Tam, Cuccui, Jon, Wren, Brendan W

“…The substantial rise in multidrug-resistant bacterial infections is a current global imperative. Cumulative efforts to characterize antimicrobial resistance in…”
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Extracellular DNA, cell surface proteins and c-di-GMP promote biofilm formation in Clostridioides difficile by Dawson, Lisa F., Peltier, Johann, Hall, Catherine L., Harrison, Mark A., Derakhshan, Maria, Shaw, Helen A., Fairweather, Neil F., Wren, Brendan W.

“…Clostridioides difficile is the leading cause of nosocomial antibiotic-associated diarrhoea worldwide, yet there is little insight into intestinal tract…”
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Re-annotation and re-analysis of the Campylobacter jejuni NCTC11168 genome sequence by Gundogdu, Ozan, Bentley, Stephen D, Holden, Matt T, Parkhill, Julian, Dorrell, Nick, Wren, Brendan W

“…Campylobacter jejuni is the leading bacterial cause of human gastroenteritis in the developed world. To improve our understanding of this important human…”
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