Search Results - "WOOLEY, Karen L"

Design of polymeric nanoparticles for biomedical delivery applications by Elsabahy, Mahmoud, Wooley, Karen L

“…Polymeric nanoparticles-based therapeutics show great promise in the treatment of a wide range of diseases, due to the flexibility in which their structures…”
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Polymeric Nanostructures for Imaging and Therapy by Elsabahy, Mahmoud, Heo, Gyu Seong, Lim, Soon-Mi, Sun, Guorong, Wooley, Karen L

“…A study investigagted the effectiveness of polymeric nanostructures for diagnostic efficacy. Topics addressed include the design of polymer nanostructures to…”
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Absorbable hemostatic hydrogels comprising composites of sacrificial templates and honeycomb-like nanofibrous mats of chitosan by Leonhardt, Eric E., Kang, Nari, Hamad, Mostafa A., Wooley, Karen L., Elsabahy, Mahmoud

“…The development of hemostatic technologies that suit a diverse range of emergency scenarios is a critical initiative, and there is an increasing interest in…”
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Convergence of Synthetic Organic and Polymer Chemistries by Hawker, Craig J, Wooley, Karen L

“…Several recent conceptual advances, which take advantage of the design criteria and practical techniques of molecular-level control in organic chemistry, allow…”
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Advancing the Development of Highly-Functionalizable Glucose‑Based Polycarbonates by Tuning of the Glass Transition Temperature by Song, Yue, Ji, Xiaozhou, Dong, Mei, Li, Richen, Lin, Yen-Nan, Wang, Hai, Wooley, Karen L

“…Fundamental studies that gain an understanding of the tunability of physical properties of natural product-based polymers are vital for optimizing their…”
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Monomer design strategies to create natural product-based polymer materials by Kristufek, Samantha L, Wacker, Kevin T, Tsao, Yi-Yun Timothy, Su, Lu, Wooley, Karen L

“…Covering: 2010-Aug. 2016In an effort towards enhancing function and sustainability, natural products have become of interest in the field of polymer chemistry…”
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Block Copolymer Assembly via Kinetic Control by Cui, Honggang, Chen, Zhiyun, Zhong, Sheng, Wooley, Karen L, Pochan, Darrin J

“…Block copolymers consist of two or more chemically different polymer segments, or blocks, connected by a covalent linkage. In solution, amphiphilic blocks can…”
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Dynamic Cylindrical Assembly of Triblock Copolymers by a Hierarchical Process of Covalent and Supramolecular Interactions by Li, Zhou, Ma, Jun, Lee, Nam S, Wooley, Karen L

“…We have developed a hierarchical process that combines linear triblock copolymers into concentric globular subunits through strong chemical bonds and is…”
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Organocatalyzed ROP of a Glucopyranoside Derived Five-Membered Cyclic Carbonate by Felder, Simcha E, Redding, McKenna J, Noel, Amandine, Grayson, Scott M, Wooley, Karen L

“…Saccharides, based on their wide bioavailability, high chemical functionality and stereochemical diversity, are attractive starting materials for the…”
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Degradability of Poly(Lactic Acid)-Containing Nanoparticles: Enzymatic Access through a Cross-Linked Shell Barrier by Samarajeewa, Sandani, Shrestha, Ritu, Li, Yali, Wooley, Karen L

“…Comparative studies of bulk samples of hydrolytically degradable poly(lactic acid) (PLA) vs core–shell block copolymer micelles having PLA cores revealed…”
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Applications of Orthogonal “Click” Chemistries in the Synthesis of Functional Soft Materials by Iha, Rhiannon K, Wooley, Karen L, Nyström, Andreas M, Burke, Daniel J, Kade, Matthew J, Hawker, Craig J

“…The use of orthogonal chemistry in the production of functional soft materials is discussed. Nanoscale structure, complex polymers, and biological systems are…”
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Rapid and Versatile Construction of Diverse and Functional Nanostructures Derived from a Polyphosphoester-Based Biomimetic Block Copolymer System by Zhang, Shiyi, Zou, Jiong, Zhang, Fuwu, Elsabahy, Mahmoud, Felder, Simcha E, Zhu, Jiahua, Pochan, Darrin J, Wooley, Karen L

“…A rapid and efficient approach for the preparation and modification of a versatile class of functional polymer nanoparticles has been developed, for which the…”
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Polycarbonates Derived from Glucose via an Organocatalytic Approach by Mikami, Koichiro, Lonnecker, Alexander T, Gustafson, Tiffany P, Zinnel, Nathanael F, Pai, Pei-Jing, Russell, David H, Wooley, Karen L

“…An organocatalyzed ring-opening polymerization methodology was developed for the preparation of polycarbonates derived from glucose as a natural product…”
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The Importance of Chemistry in Creating Well-Defined Nanoscopic Embedded Therapeutics: Devices Capable of the Dual Functions of Imaging and Therapy by Nyström, Andreas M, Wooley, Karen L

“…Nanomedicine is a rapidly evolving field, for which polymer building blocks are proving useful for the construction of sophisticated devices that provide…”
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Facile Synthesis of Clickable, Water-Soluble, and Degradable Polyphosphoesters by Zhang, Shiyi, Li, Ang, Zou, Jiong, Lin, Lily Yun, Wooley, Karen L

“…“Click” chemistry is a library of efficient and reliable reactions, which have been used to functionalize various classes of bio- and synthetic macromolecular…”
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Preparation and in Vitro Antimicrobial Activity of Silver-Bearing Degradable Polymeric Nanoparticles of Polyphosphoester-block-Poly(l‑lactide) by Lim, Young H, Tiemann, Kristin M, Heo, Gyu Seong, Wagers, Patrick O, Rezenom, Yohannes H, Zhang, Shiyi, Zhang, Fuwu, Youngs, Wiley J, Hunstad, David A, Wooley, Karen L

“…The development of well-defined polymeric nanoparticles (NPs) as delivery carriers for antimicrobials targeting human infectious diseases requires rational…”
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Morphologic design of nanostructures for enhanced antimicrobial activity by Sayed, Fatma Al-Zahraa, Eissa, Noura G, Shen, Yidan, Hunstad, David A, Wooley, Karen L, Elsabahy, Mahmoud

“…Despite significant progress in synthetic polymer chemistry and in control over tuning the structures and morphologies of nanoparticles, studies on morphologic…”
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A Tale of Drug-Carrier Optimization: Controlling Stimuli Sensitivity via Nanoparticle Hydrophobicity through Drug Loading by Lin, Yen-Nan, Khan, Sarosh, Song, Yue, Dong, Mei, Shen, Yidan, Tran, David K, Pang, Ching, Zhang, Fuwu, Wooley, Karen L

“…Interactions between drug molecules, nanocarrier components, and surrounding media influence the properties and therapeutic efficacies of nanomedicines. In…”
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Functional Polycarbonate of a d‑Glucal-Derived Bicyclic Carbonate via Organocatalytic Ring-Opening Polymerization by Lonnecker, Alexander T, Lim, Young H, Wooley, Karen L

“…Herein, we demonstrate the synthesis of a bicyclic carbonate monomer of a d-glucal derivative, which originated from the natural product d-glucose, in an…”
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Nanoscopic Cylindrical Dual Concentric and Lengthwise Block Brush Terpolymers as Covalent Preassembled High-Resolution and High-Sensitivity Negative-Tone Photoresist Materials by Sun, Guorong, Cho, Sangho, Clark, Corrie, Verkhoturov, Stanislav V, Eller, Michael J, Li, Ang, Pavía-Jiménez, Adriana, Schweikert, Emile A, Thackeray, James W, Trefonas, Peter, Wooley, Karen L

“…We describe a high-resolution, high-sensitivity negative-tone photoresist technique that relies on bottom-up preassembly of differential polymer components…”
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