Search Results - "WOODWORTH, Craig D"

Establishment and optimization of epithelial cell cultures from human ectocervix, transformation zone, and endocervix optimization of epithelial cell cultures by Deng, Han, Mondal, Sumona, Sur, Shantanu, Woodworth, Craig D.

“…Cervical cancer is a major public health problem and research using cell culture models has improved understanding of this disease. The human cervix contains…”
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Magnetic Field-Activated Sensing of mRNA in Living Cells by Bakshi, Saira F, Guz, Nataliia, Zakharchenko, Andrey, Deng, Han, Tumanov, Alexei V, Woodworth, Craig D, Minko, Sergiy, Kolpashchikov, Dmitry M, Katz, Evgeny

“…Detection of specific mRNA in living cells has attracted significant attention in the past decade. Probes that can be easily delivered into cells and activated…”
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Susceptibility of epithelial cells cultured from different regions of human cervix to HPV16-induced immortalization by Deng, Han, Hillpot, Eric, Yeboah, Philomina, Mondal, Sumona, Woodworth, Craig D

“…Persistent infection with high-risk human papillomavirus (HPV) is a major risk factor for cervical cancer. Greater than 90% of these cancers originate in the…”
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Towards early detection of cervical cancer: Fractal dimension of AFM images of human cervical epithelial cells at different stages of progression to cancer by Guz, Nataliia V., PhD, Dokukin, Maxim E., PhD, Woodworth, Craig D., PhD, Cardin, Andrew, Sokolov, Igor, PhD

“…Abstract We used AFM HarmoniX modality to analyse the surface of individual human cervical epithelial cells at three stages of progression to cancer, normal,…”
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Fundamental differences in cell cycle deregulation in human papillomavirus-positive and human papillomavirus-negative head/neck and cervical cancers by PYEON, Dohun, NEWTON, Michael A, KELSEY, Karl T, TUREK, Lubomir P, AHLQUIST, Paul, LAMBERT, Paul F, DEN BOON, Johan A, SENGUPTA, Srikumar, MARSIT, Carmen J, WOODWORTH, Craig D, CONNOR, Joseph P, HAUGEN, Thomas H, SMITH, Elaine M

“…Human papillomaviruses (HPV) are associated with nearly all cervical cancers, 20% to 30% of head and neck cancers (HNC), and other cancers. Because HNCs also…”
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Nanoreactors based on DNAzyme-functionalized magnetic nanoparticles activated by magnetic field by Bakshi, Saira F, Guz, Nataliia, Zakharchenko, Andrey, Deng, Han, Tumanov, Alexei V, Woodworth, Craig D, Minko, Sergiy, Kolpashchikov, Dmitry M, Katz, Evgeny

“…A new biomimetic nanoreactor design, MaBiDz, is presented based on a copolymer brush in combination with superparamagnetic nanoparticles. This cellular…”
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Recovery of aging-related size increase of skin epithelial cells: in vivo mouse and in vitro human study by Sokolov, Igor, Guz, Natali V, Iyer, Swaminathan, Hewitt, Amy, Sokolov, Nina A, Erlichman, Joseph S, Woodworth, Craig D

“…The size increase of skin epithelial cells during aging is well-known. Here we demonstrate that treatment of aging cells with cytochalasin B substantially…”
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Recovery of elasticity of aged human epithelial cells in vitro by Sokolov, Igor, Iyer, Swaminathan, Woodworth, Craig D.

“…We recently found a considerable increase in rigidity of human epithelial cells during aging in vitro. This is important because the loss in elasticity of…”
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Inhibition of the epidermal growth factor receptor increases expression of genes that stimulate inflammation, apoptosis, and cell attachment by Woodworth, Craig D, Michael, Evan, Marker, Dan, Allen, Sarah, Smith, Laura, Nees, Matthias

“…The epidermal growth factor receptor (EGFR) is overexpressed in several types of human cancer, and inhibition of EGFR function is a promising strategy for…”
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HPV16-Immortalized Cells from Human Transformation Zone and Endocervix are More Dysplastic than Ectocervical Cells in Organotypic Culture by Deng, Han, Hillpot, Eric, Mondal, Sumona, Khurana, Kamal K., Woodworth, Craig D.

“…A major risk factor for cervical cancer is persistent infection with high-risk human papillomaviruses (HPV) which can cause cervical intraepithelial neoplasia…”
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Ivermectin-induced cell death of cervical cancer cells in vitro a consequence of precipitate formation in culture media by Qabbus, Manal Bin, Hunt, Katey S., Dynka, Joshua, Woodworth, Craig D., Sur, Shantanu, Samways, Damien S.K.

“…The anthelmintic ivermectin has been reported to possess anticancer and antiviral efficacy. However, the effective concentrations reported in vitro are near…”
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KCa3.1-dependent uptake of the cytotoxic DNA-binding dye Hoechst 33258 into cancerous but not healthy cervical cells by Bukhari, Maurish, Deng, Han, Sipes, Darren, Ruane-Foster, Marisa, Purdy, Kayla, Woodworth, Craig D., Sur, Shantanu, Samways, Damien S.K.

“…The poor and nonselective penetration of current chemotherapeutics across the plasma membranes of cancer cells, which is necessary for the targeted disruption…”
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Human epithelial cells increase their rigidity with ageing in vitro: direct measurements by Berdyyeva, Tamara K, Woodworth, Craig D, Sokolov, Igor

“…The decrease in elasticity of epithelial tissues with ageing contributes to many human diseases. This change was previously attributed to increased…”
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Selective permeabilization of cervical cancer cells to an ionic DNA-binding cytotoxin by activation of P2Y receptors by Bukhari, Maurish, Deng, Han, Jones, Noelle, Towne, Zachary, Woodworth, Craig D., Samways, Damien S.K.

“…•ATP stimulated uptake of the cytotoxin, Hoechst 33258, into cervical epithelial cells.•The mechanism was dependent on P2Y receptors and independent of P2X7…”
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Papillomavirus Type 16 Oncogenes Downregulate Expression of Interferon-Responsive Genes and Upregulate Proliferation-Associated and NF-κB-Responsive Genes in Cervical Keratinocytes by Nees, Matthias, Geoghegan, Joel M., Hyman, Tehila, Frank, Stephan, Miller, Lance, Woodworth, Craig D.

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Towards Nonspecific Detection of Malignant Cervical Cells with Fluorescent Silica Beads by Iyer, Swaminathan, Woodworth, Craig D., Gaikwad, Ravi M., Kievsky, Yaroslav Y., Sokolov, Igor

“…To date, the methods for detection of cancer cells are mostly based on traditional techniques used in biology, such as visual identification of malignant…”
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Inhibition of the epidermal growth factor receptor by erlotinib prevents immortalization of human cervical cells by Human Papillomavirus type 16 by Woodworth, Craig D, Diefendorf, Laura P, Jette, David F, Mohammed, Abdulmajid, Moses, Michael A, Searleman, Sylvia A, Stevens, Dan A, Wilton, Katelynn M, Mondal, Sumona

“…Abstract The Human Papillomavirus type-16 (HPV-16) E6 and E7 oncogenes are selectively retained and expressed in cervical carcinomas, and expression of E6 and…”
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Inhibitory effect of Bcl-2 on p53-mediated transactivation following genotoxic stress by ZHAN, Q, KONTNY, U, IGLESIAS, M, ALAMO, I. JR, YU, K, HOLLANDER, M. C, WOODWORTH, C. D, FORNACE, A. J

“…In the cellular response to genotoxic stress, cell cycle checkpoint and apoptosis are considered to be two of the major biological events in maintaining…”
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Human papillomavirus type 16 E6 and E 7 proteins alter NF-kB in cultured cervical epithelial cells and inhibition of NF-kB promotes cell growth and immortalization by Vandermark, Erik R, Deluca, Krysta A, Gardner, Courtney R, Marker, Daniel F, Schreiner, Cynthia N, Strickland, David A, Wilton, Katelynn M, Mondal, Sumona, Woodworth, Craig D

“…Abstract The NF-kB family of transcription factors regulates important biological functions including cell growth, survival and the immune response. We found…”
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Detection of cancerous cervical cells using physical adhesion of fluorescent silica particles and centripetal force by Gaikwad, Ravi M, Dokukin, Maxim E, Iyer, K Swaminathan, Woodworth, Craig D, Volkov, Dmytro O, Sokolov, Igor

“…Here we describe a non-traditional method to identify cancerous human cervical epithelial cells in a culture dish based on physical adhesion between silica…”
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