Search Results - "WOODWARD, Ruth"
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Structure-based design of a single-chain triple-disulfide-stabilized fusion-glycoprotein trimer that elicits high-titer neutralizing responses against human metapneumovirus
Published in PLoS pathogens (01-09-2023)“…The Pneumoviridae family of viruses includes human metapneumovirus (HMPV) and respiratory syncytial virus (RSV). The closely related Paramyxoviridae family…”
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2
Cholesterol reduction by immunization with a PCSK9 mimic
Published in Cell reports (Cambridge) (25-06-2024)“…Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a plasma protein that controls cholesterol homeostasis. Here, we design a human PCSK9 mimic, named…”
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3
Terahertz pulse imaging in reflection geometry of human skin cancer and skin tissue
Published in Physics in medicine & biology (07-11-2002)“…We demonstrate the application of terahertz pulse imaging (TPI) in reflection geometry for the study of skin tissue and related cancers both in vitro and in…”
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Terahertz Pulse Imaging of ex vivo Basal Cell Carcinoma
Published in Journal of investigative dermatology (01-01-2003)“…Terahertz pulse imaging has been used for the first time to study basal cell carcinoma ex vivo, the most common form of skin cancer. This noninvasive technique…”
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5
Reproductive consequences of a matrilineal overthrow in rhesus monkeys
Published in American journal of primatology (01-03-2015)“…Matrilineal overthrows in macaque societies are rare but devastating events, often resulting in severe morbidity, mortality, and loss of individual and group…”
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6
CD4-Like Immunological Function by CD4− T Cells in Multiple Natural Hosts of Simian Immunodeficiency Virus
Published in Journal of Virology (01-09-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Anti-viral efficacy of a next-generation CD4-binding site bNAb in SHIV-infected animals in the absence of anti-drug antibody responses
Published in iScience (21-10-2022)“…Broadly neutralizing antibodies (bNAbs) against HIV-1 are promising immunotherapeutic agents for treatment of HIV-1 infection. bNAbs can be administered to…”
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8
Mitochondrial compromise in 3-year old patas monkeys exposed in utero to human-equivalent antiretroviral therapies
Published in Environmental and molecular mutagenesis (01-08-2016)“…Antiretroviral (ARV) drug therapy, given during pregnancy for prevention of mother‐to‐child transmission of human immunodeficiency virus 1 (HIV‐1), induces…”
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Perinatal Exposure of Patas Monkeys to Antiretroviral Nucleoside Reverse-Transcriptase Inhibitors Induces Genotoxicity Persistent for up to 3 Years of Age
Published in The Journal of infectious diseases (15-07-2013)“…Background. Erythrocebus patas (patas) monkeys were used to model antiretroviral (ARV) drug in human immunodeficiency virus type 1—infected pregnant women…”
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10
Facial asymmetry is negatively related to condition in female macaque monkeys
Published in Behavioral ecology and sociobiology (01-09-2012)“…The face is an important visual trait in social communication across many species. In evolutionary terms, there are large and obvious selective advantages in…”
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Differential relationships between chronic hormone profiles in pregnancy and maternal investment in rhesus monkey mothers with hair loss in the neonatal period
Published in American journal of primatology (01-01-2017)“…Hair loss is commonly used as an indicator of well being in primate facilities, yet it has been shown to also occur in otherwise healthy pregnant and…”
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The Influence of Age on Serum Concentrations of Cardiac Troponin I: Results in Rats, Monkeys, and Commercial Sera
Published in Toxicologic pathology (01-07-2014)“…Cardiac troponins serve as serum biomarkers of myocardial injury. The current study examined the influence of age on serum concentrations of cardiac troponin I…”
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13
Tamoxifen–DNA adduct formation in monkey and human reproductive organs
Published in Carcinogenesis (New York) (01-05-2014)“…The estrogen analog tamoxifen (TAM), used for adjuvant therapy of breast cancer, induces endometrial and uterine tumors in breast cancer patients…”
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14
Terahertz pulsed imaging and spectroscopy for biomedical and pharmaceutical applications
Published in Faraday discussions (01-01-2004)“…Terahertz (THz) radiation lies between the infrared and microwave regions of the electromagnetic spectrum. Advances in THz technology have opened up many…”
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15
Genetic diversity of Klebsiella pneumoniae isolates during an outbreak in a non-human primate research colony
Published in Journal of medical primatology (01-12-2016)“…Background Klebsiella pneumoniae can be a serious pathogen in non‐human primates, particularly Neotropical monkeys. Methods During a K. pneumoniae outbreak in…”
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The effect of gonadectomy on prepulse inhibition and fear-potentiated startle in adolescent rhesus macaques
Published in Psychoneuroendocrinology (01-07-2010)“…Summary Sex steroids, such as testosterone, can regulate brain development, cognition and modify psychiatric conditions. However, the role of adolescent…”
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Gonadectomy negatively impacts social behavior of adolescent male primates
Published in Hormones and behavior (01-06-2009)“…Social behavior changes dramatically during primate adolescence. However, the extent to which testosterone and other gonadal hormones are necessary for…”
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Successful behavioral strategy to unite mother and infant rhesus monkeys (Macaca mulatta) after cesarean delivery
Published in American journal of primatology (01-06-2009)“…Developmental studies of pre‐ to postnatal continuities in rhesus monkeys sometimes require infants be reared with their mothers. However, complications during…”
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Effect of tryptophan treatment on self-biting and central nervous system serotonin metabolism in rhesus monkeys (Macaca mulatta)
Published in Neuropsychopharmacology (New York, N.Y.) (01-10-1998)“…Two studies were conducted to examine the effects of oral L-tryptophan (TRP) supplementation as a treatment for self-injurious behavior (SIB) and to…”
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Potent suppression of viral rebound after analytical treatment interruption in ART-suppressed SHIV-infected animals by a CD4 binding site bNAb
Published in The Journal of immunology (1950) (01-05-2023)“…Abstract Broadly neutralizing antibodies (bNAbs) are promising immunotherapeutic biological agents against HIV-1 that can be used to complement small-molecule…”
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