Search Results - "WOODLAND, D. L"

Activated Antigen-Specific CD8+ T Cells Persist in the Lungs Following Recovery from Respiratory Virus Infections by Hogan, Robert J, Usherwood, Edward J, Zhong, Weimin, Roberts, Alan D, Dutton, Richard W, Harmsen, Allen G, Woodland, David L

“…The poor correlation between cellular immunity to respiratory virus infections and the numbers of memory CD8(+) T cells in the secondary lymphoid organs…”
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Antigen-Specific CD8+ T Cells Persist in the Upper Respiratory Tract Following Influenza Virus Infection by Wiley, James A, Hogan, Robert J, Woodland, David L, Harmsen, Allen G

“…Because little is known about lymphocyte responses in the nasal mucosa, lymphocyte accumulation in the nasal mucosa, nasal-associated lymphoid tissue (NALT),…”
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Jump-starting the immune system: prime-boosting comes of age by Woodland, David L

“…A major challenge for immunologists has been the development of vaccines designed to emphasize cellular immune responses. One particularly promising approach…”
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Latent Antigen Vaccination in a Model Gammaherpesvirus Infection by Usherwood, E J, Ward, K A, Blackman, M A, Stewart, J P, Woodland, D L

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Production of Calcium-Mobilizing Metabolites by a Novel Member of the ADP-Ribosyl Cyclase Family Expressed in Schistosoma mansoni by Goodrich, Stephen P, Muller-Steffner, Hélène, Osman, Ahmed, Moutin, Marie-Jo, Kusser, Kim, Roberts, Alan, Woodland, David L, Randall, Troy D, Kellenberger, Esther, LoVerde, Philip T, Schuber, Francis, Lund, Frances E

“…ADP-ribosyl cyclases are structurally conserved enzymes that are best known for catalyzing the production of the calcium-mobilizing metabolite, cyclic…”
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Heterologous protection against lethal A/HongKong/156/97 (H5N1) influenza virus infection in C57BL/6 mice by O'Neill, Eduardo, Krauss, Scott L, Riberdy, Janice M, Webster, Robert G, Woodland, David L

“…Department of Virology and Molecular Biology 1 and Department of Immunology 2 , St Jude Children’s Research Hospital, Memphis, TN 38105-2794, USA Author for…”
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Cellular immunity and memory to respiratory virus infections by Woodland, D L, Hogan, R J, Zhong, W

“…Respiratory virus infections, such as those caused by influenza and parainfluenza viruses, are a major cause of morbidity and mortality worldwide. Current…”
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Antibody-Independent Antiviral Function of Memory CD4+ T Cells In Vivo Requires Regulatory Signals from CD8+ Effector T Cells by Zhong, Weimin, Roberts, Alan D, Woodland, David L

“…Previous studies have shown that vaccine-primed CD4(+) T cells can mediate accelerated clearance of respiratory virus infection. However, the relative…”
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Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity by Randall, Troy D, Moyron-Quiroz, Juan E, Rangel-Moreno, Javier, Kusser, Kim, Hartson, Louise, Sprague, Frank, Goodrich, Stephen, Woodland, David L, Lund, Frances E

“…Bronchus-associated lymphoid tissue (BALT) is occasionally found in the lungs of mice and humans; however, its role in respiratory immunity is unknown. Here we…”
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Analysis of Virus-Specific CD4+ T Cells during Long-Term Gammaherpesvirus Infection by Flaño, Emilio, Woodland, David L., Blackman, Marcia A., Doherty, Peter C.

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Endogenous superantigen expression is controlled by mouse mammary tumor proviral loci by WOODLAND, D. L, LUND, F. E, HAPP, M. P, BLACKMAN, M. A, PALMER, E, CORLEY, R. B

“…Superantigens are defined by their ability to stimulate T cells based predominantly on their V beta expression and ability to delete T cells in the thymus when…”
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Immunodominance of major histocompatibility complex class I-restricted influenza virus epitopes can be influenced by the T-cell receptor repertoire by Daly, K, Nguyen, P, Woodland, D L, Blackman, M A

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Activated Primary and Memory CD8 T Cells Migrate to Nonlymphoid Tissues Regardless of Site of Activation or Tissue of Origin by Masopust, David, Vezys, Vaiva, Usherwood, Edward J, Cauley, Linda S, Olson, Sara, Marzo, Amanda L, Ward, Richard L, Woodland, David L, Lefrancois, Leo

“…Following activation within secondary lymphoid tissue, CD8 T cells must migrate to targets, such as infected self tissue, allografts, and tumors, to mediate…”
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Major histocompatibility complex-specific recognition of Mls-1 is mediated by multiple elements of the T cell receptor by WOODLAND, D. L, SMITH, H. P, SURMAN, S, PHUONG LE, RENREN WEN, BLACKMAN, M. A

“…We have recently shown that recognition of the mouse mammary tumor virus 9-associated superantigen (vSAG-9) by murine V beta 17+ T cells is strongly influenced…”
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Protection from respiratory virus infections can be mediated by antigen-specific CD4(+) T cells that persist in the lungs by Hogan, R J, Zhong, W, Usherwood, E J, Cookenham, T, Roberts, A D, Woodland, D L

“…Although CD4(+) T cells have been shown to mediate protective cellular immunity against respiratory virus infections, the underlying mechanisms are poorly…”
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Latent murine gamma-herpesvirus infection is established in activated B cells, dendritic cells, and macrophages by Flaño, E, Husain, S M, Sample, J T, Woodland, D L, Blackman, M A

“…Intranasal infection of mice with the murine gamma-herpesvirus MHV-68 results in an acute lytic infection in the lung, followed by the establishment of…”
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Virus-Specific CD8 + T Cells in Primary and Secondary Influenza Pneumonia by Flynn, Kirsten J, Belz, Gabrielle T, Altman, John D, Ahmed, Rafi, Woodland, David L, Doherty, Peter C

“…Virus-specific CD8 + effector T cells (eCTL) are enriched in the lungs of mice with primary influenza pneumonia, though later detection of memory T cells…”
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Gamma-herpesvirus latency is preferentially maintained in splenic germinal center and memory B cells by Flaño, Emilio, Kim, In-Jeong, Woodland, David L, Blackman, Marcia A

“…The gamma-herpesviruses are oncogenic B cell lymphotrophic viruses that establish life-long latency in the host. Murine gamma-herpesvirus 68 (MHV-68) infection…”
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Cell-mediated immunity to respiratory virus infections by Woodland, David L

“…The mucosal surfaces of the lungs pose tremendous problems for an immune system charged with maintaining a sterile pulmonary environment. Despite these…”
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In vivo effects of superantigens by Blackman, M A, Woodland, D L

“…Superantigens are potent immunostimulatory molecules that activate both T cells and antigen presenting cells. The consequences of superantigen exposure range…”
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