Search Results - "WOOD, JOHN C."

Guidelines for quantifying iron overload by Wood, John C

“…Both primary and secondary iron overload are increasingly prevalent in the United States because of immigration from the Far East, increasing transfusion…”
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Use of Magnetic Resonance Imaging to Monitor Iron Overload by Wood, John C., MD, PhD

“…Treatment of iron overload requires robust estimates of total-body iron burden and its response to iron chelation therapy. Compliance with chelation therapy…”
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Impact of iron assessment by MRI by Wood, John C

“…The use of magnetic resonance imaging (MRI) to estimate tissue iron was conceived in the 1980s, but has only become a practical reality in the last decade. The…”
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History and current impact of cardiac magnetic resonance imaging on the management of iron overload by Wood, John C

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On T2 Magnetic Resonance and Cardiac Iron by CARPENTER, John-Paul, TAIGANG HE, GALANELLO, Renzo, FORNI, Gianluca, CATANI, Gualtiero, MATTA, Gildo, FUCHAROEN, Suthat, FLEMING, Adam, HOUSE, Michael J, BLACK, Greg, FIRMIN, David N, PIERRE, Timothy G. St, KIRK, Paul, PENNELL, Dudley J, ROUGHTON, Michael, ANDERSON, Lisa J, DE NORONHA, Sofia V, SHEPPARD, Mary N, PORTER, John B, WALKER, J. Malcolm, WOOD, John C

“…Measurement of myocardial iron is key to the clinical management of patients at risk of siderotic cardiomyopathy. The cardiovascular magnetic resonance…”
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Relaxivity-iron calibration in hepatic iron overload: Probing underlying biophysical mechanisms using a Monte Carlo model by Ghugre, Nilesh R., Wood, John C.

“…Iron overload is a serious condition for patients with β‐thalassemia, transfusion‐dependent sickle cell anemia, and inherited disorders of iron metabolism. MRI…”
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Mental stress causes vasoconstriction in subjects with sickle cell disease and in normal controls by Shah, Payal, Khaleel, Maha, Thuptimdang, Wanwara, Sunwoo, John, Veluswamy, Saranya, Chalacheva, Patjanaporn, Kato, Roberta M, Detterich, Jon, Wood, John C, Zeltzer, Lonnie, Sposto, Richard, Khoo, Michael C K, Coates, Thomas D

“…Vaso-occlusive crisis (VOC) is a hallmark of sickle cell disease (SCD) and occurs when deoxygenated sickled red blood cells occlude the microvasculature. Any…”
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Anemia Increases Oxygen Extraction Fraction in Deep Brain Structures but Not in the Cerebral Cortex by Shen, Jian, Miao, Xin, Vu, Chau, Xu, Botian, González-Zacarías, Clio, Nederveen, Aart J, Wood, John C

“…Sickle cell disease (SCD) is caused by a single amino acid mutation in hemoglobin, causing chronic anemia and neurovascular complications. However, the effects…”
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Dynamic MR imaging of cerebral perfusion during bicycling exercise by Mast, Isa H., Baas, Koen P.A., Jørstad, Harald T., Wood, John C., Nederveen, Aart J., Bakermans, Adrianus J.

“…Habitual physical activity is beneficial for cerebrovascular health and cognitive function. Physical exercise therefore constitutes a clinically relevant…”
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Imputation models and error analysis for phase contrast MR cerebral blood flow measurements by Shah, Payal, Doyle, Eamon, Wood, John C, Borzage, Matthew T

“…Cerebral blood flow (CBF) supports brain metabolism. Diseases impair CBF, and pharmacological agents modulate CBF. Many techniques measure CBF, but phase…”
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Pancreatic iron loading predicts cardiac iron loading in thalassemia major by Noetzli, Leila J., Papudesi, Jhansi, Coates, Thomas D., Wood, John C.

“…Diabetes mellitus and cardiomyopathy are common in chronically transfused thalassemia major patients, occurring in the second and third decades of life. We…”
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Elevated liver iron concentration is a marker of increased morbidity in patients with β thalassemia intermedia by MUSALLAM, Khaled M, CAPPELLINI, Maria Domenica, WOOD, John C, MOTTA, Irene, GRAZIADEI, Giovanna, TAMIM, Hani, TAHER, Ali T

“…Patients with β thalassemia intermedia can have substantial iron overload, irrespectively of their transfusion status, secondary to increased intestinal iron…”
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Assessment of functional shunting in patients with sickle cell disease by Afzali-Hashemi, Liza, Václavů, Lena, Wood, John C, Biemond, Bart J, Nederveen, Aart J, Mutsaerts, Henk J M M, Schrantee, Anouk

“…Silent cerebral infarcts (SCI) are common in patients with sickle cell disease (SCD) and are thought to be caused by a mismatch between oxygen delivery and…”
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MRI R2 and R2 mapping accurately estimates hepatic iron concentration in transfusion-dependent thalassemia and sickle cell disease patients by Wood, John C., Enriquez, Cathleen, Ghugre, Nilesh, Tyzka, J. Michael, Carson, Susan, Nelson, Marvin D., Coates, Thomas D.

“…Measurements of hepatic iron concentration (HIC) are important predictors of transfusional iron burden and long-term outcome in patients with…”
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Intramyocardial hemorrhage drives fatty degeneration of infarcted myocardium by Cokic, Ivan, Chan, Shing Fai, Guan, Xingmin, Nair, Anand R., Yang, Hsin-Jung, Liu, Ting, Chen, Yinyin, Hernando, Diego, Sykes, Jane, Tang, Richard, Butler, John, Dohnalkova, Alice, Kovarik, Libor, Finney, Robert, Kali, Avinash, Sharif, Behzad, Bouchard, Louis S., Gupta, Rajesh, Krishnam, Mayil Singaram, Vora, Keyur, Tamarappoo, Balaji, Howarth, Andrew G., Kumar, Andreas, Francis, Joseph, Reeder, Scott B., Wood, John C., Prato, Frank S., Dharmakumar, Rohan

“…Sudden blockage of arteries supplying the heart muscle contributes to millions of heart attacks (myocardial infarction, MI) around the world. Although…”
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Hemodynamic provocation with acetazolamide shows impaired cerebrovascular reserve in adults with sickle cell disease by Václavů, Lena, Meynart, Benoit N, Mutsaerts, Henri J M M, Petersen, Esben Thade, Majoie, Charles B L M, VanBavel, Ed T, Wood, John C, Nederveen, Aart J, Biemond, Bart J

“…Sickle cell disease is characterized by chronic hemolytic anemia and vascular inflammation, which can diminish the vasodilatory capacity of the small…”
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The effect of deferasirox on cardiac iron in thalassemia major: impact of total body iron stores by Wood, John C., Kang, Barinder P., Thompson, Alexis, Giardina, Patricia, Harmatz, Paul, Glynos, Tara, Paley, Carole, Coates, Thomas D.

“…We present results from a prospective, multicenter, open-label, single-arm study evaluating response of cardiac and liver iron to deferasirox therapy for 18…”
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Pancreatic iron and glucose dysregulation in thalassemia major by Noetzli, Leila J., Mittelman, Steven D., Watanabe, Richard M., Coates, Thomas D., Wood, John C.

“…Pancreatic iron overload and diabetes mellitus (DM) are common in thalassemia major patients. However, the relationship between iron stores and glucose…”
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MRI Restoration Using Edge-Guided Adversarial Learning by Chai, Yaqiong, Xu, Botian, Zhang, Kangning, Lepore, Natasha, Wood, John C.

“…Magnetic resonance imaging (MRI) images acquired as multislice two-dimensional (2D) images present challenges when reformatted in orthogonal planes due to…”
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Biophysical markers of the peripheral vasoconstriction response to pain in sickle cell disease by Chalacheva, Patjanaporn, Khaleel, Maha, Sunwoo, John, Shah, Payal, Detterich, Jon A, Kato, Roberta M, Thuptimdang, Wanwara, Meiselman, Herbert J, Sposto, Richard, Tsao, Jennie, Wood, John C, Zeltzer, Lonnie, Coates, Thomas D, Khoo, Michael C K

“…Painful vaso-occlusive crisis (VOC), a complication of sickle cell disease (SCD), occurs when sickled red blood cells obstruct flow in the microvasculature. We…”
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