Search Results - "WOO, E. S"
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1
Statin induces apoptosis of human colon cancer cells and downregulation of insulin-like growth factor 1 receptor via proapoptotic ERK activation
Published in Oncology letters (01-07-2016)“…Insulin-like growth factor 1 (IGF-1) and IGF-1 receptor (IGF-1R) signaling plays an important role in tumor progression in patients with certain…”
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2
Metallothionein null cells have increased sensitivity to anticancer drugs
Published in Cancer research (Chicago, Ill.) (15-05-1995)“…Overexpression of metallothioneins (MTs) protects some cells against heavy metals, mutagens, anticancer agents, and reactive oxygen species. We have examined…”
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3
Nucleocytoplasmic functionality of metallothionein
Published in Cancer research (Chicago, Ill.) (01-10-1997)“…Appropriate nucleocytoplasmic partitioning of proteins can direct diverse cellular processes. Metallothioneins (MTs) are thiol-rich, stress-inducible proteins…”
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4
DNA polymerase arrest by adducted trivalent chromium
Published in Molecular carcinogenesis (01-03-1994)“…Carcinogenic chromium (Cr6+) enters cells via the sulfate transport system and undergoes intracellular reduction to trivalent chromium, which strongly adducts…”
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5
Cell cycle dependent subcellular distribution of Cdc25B subtypes
Published in Oncogene (29-04-1999)“…The dual specificity phosphatase and oncogene Cdc25B has been implicated in the G2/M cell cycle checkpoint, but the mode by which it is regulated remains…”
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6
Human metallothionein isoform gene expression in cisplatin-sensitive and resistant cells
Published in Molecular pharmacology (01-03-1994)“…Overexpression of metallothioneins (MTs) has been observed in some cis-diamminedichloroplatinum (CDDP)-resistant cells. We have developed oligonucleotide…”
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7
Real-time molecular and cellular analysis: the new frontier of drug discovery
Published in Current Opinion in Biotechnology (01-02-2001)“…The pharmaceutical industry is currently facing the challenge of maintaining increased efficiency and productivity while contending with a deluge of genomic…”
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Book Review Journal Article -
8
Diversity of metallothionein content and subcellular localization in the National Cancer Institute tumor panel
Published in Cancer chemotherapy and pharmacology (1997)“…Metallothioneins (MTs) are major thiol-containing intracellular proteins that bind metals, are induced by stress, and have been implicated in resistance to…”
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9
Chemical synthesis and biological activity of a novel fluorescent etoposide derivative
Published in Biochemical pharmacology (07-03-1997)“…The antineoplastic activity of etoposide resides in its ability to poison the nuclear enzyme DNA topoisomerase II (topo II). The factors that control the…”
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10
Efficacy of the lancaster red-green test for the diagnosis of superior oblique palsy
Published in Optometry and vision science (01-11-2006)“…The purpose of this study was to evaluate the usefulness of the Lancaster red-green test (LRGT) in patients with superior oblique palsy (SOP). The LRGT results…”
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11
Metallothionein and HSP-72 are induced in the liver by hemorrhagic shock and resuscitation but not by shock alone
Published in Surgery (01-08-1996)“…Background. Previous reports have indicated that HSP-72 and metallothionein mRNA undergo induction in the liver after resuscitated hemorrhagic shock. In this…”
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12
The protein thiol metallothionein as an antioxidant and protectant against antineoplastic drugs
Published in Chemico-biological interactions (24-04-1998)“…Metallothioneins (MTs) are major zinc-binding protein thiols that are readily inducible and whose functions remain unclear. Recent evidence supports a role for…”
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13
Overexpression of metallothionein decreases sensitivity of pulmonary endothelial cells to oxidant injury
Published in The American journal of physiology (01-10-1997)“…Metallothionein (MT) is a low-molecular-weight cysteine-rich protein with extensive metal binding capacity and potential nonenzymatic antioxidant activity…”
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14
Energy-dependent nuclear binding dictates metallothionein localization
Published in Journal of cellular physiology (01-01-2000)“…Metallothioneins (MTs) are low molecular weight, stress‐activated proteins that protect cells against heavy metals, oxidants, and some electrophilic drugs…”
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15
Nucleophilic Distribution of Metallothionein in Human Tumor Cells
Published in Experimental cell research (01-05-1996)“…Metallothionein (MT), a major zinc-binding intracellular protein thiol, has been associated with cytoprotection from heavy metals, antineoplastic drugs,…”
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16
Iatrogenic Retinal Artery Occlusion Caused by Cosmetic Facial Filler Injections
Published in American journal of ophthalmology (01-10-2012)“…Purpose To investigate the clinical manifestations and visual prognosis of retinal artery occlusion resulting from cosmetic facial filler injections. Design…”
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17
Optic Disc Change with Incipient Myopia of Childhood
Published in Ophthalmology (Rochester, Minn.) (2012)“…Purpose To describe progressive tilting of the optic nerve head (ONH) and development/enlargement of parapapillary atrophy (PPA) observed in children with…”
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18
Differentiation of Optic Nerve Head Drusen and Optic Disc Edema with Spectral-Domain Optical Coherence Tomography
Published in Ophthalmology (Rochester, Minn.) (01-05-2011)“…Purpose To evaluate the efficacy of spectral-domain optical coherence tomography (SD-OCT) in differentiating optic disc edema (ODE) and optic nerve head drusen…”
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19
Cognitive Impairment in Age-related Macular Degeneration and Geographic Atrophy
Published in Ophthalmology (Rochester, Minn.) (01-10-2012)“…Purpose To investigate cognitive function in patients with early and late age-related macular degeneration (AMD) compared with an elderly, community-dwelling…”
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20
Retinal Nerve Fiber Layer Thickness Is Decreased in the Fellow Eyes of Patients with Unilateral Retinal Vein Occlusion
Published in Ophthalmology (Rochester, Minn.) (01-04-2011)“…Objective To investigate whether retinal nerve fiber layer (RNFL) thickness is decreased in the fellow eyes of patients with unilateral retinal vein occlusion…”
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